Results 41 to 50 of about 21,434 (231)

Clinical Recommendations for the Use of Donepezil 23 mg in Moderate-to-Severe Alzheimer's Disease in the Asia-Pacific Region

Dementia and Geriatric Cognitive Disorders Extra, 2016
Background: The ‘Asia-Pacific Expert Panel (APEX) for donepezil 23 mg' met in November 2015 to review evidence for the recently approved high dose of donepezil and to provide recommendations to help physicians in Asia make informed clinical decisions ...
Marwan Sabbagh, SeolHeui Han, SangYun Kim, Hae-Ri Na, Jae-Hong Lee, Nagaendran Kandiah, Kammant Phanthumchinda, Chuthamanee Suthisisang, Vorapun Senanarong, Ming-Chyi Pai, Diatri Narilastri, Ajit M. Sowani, Encarnita Ampil, Amitabh Dash   +13 more
doaj   +1 more source

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

Journal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto, Tonny Cley Campos Leite, Mônica Tejo Cavalcanti, Geany Targino Sousa Pedrosa, Rerisson do Nascimento Alves, Amanda Reges de Sena, Mônica Correia Gonçalves   +6 more
wiley   +1 more source

Temporal trends for donepezil utilization among older people

, 2016
To examine and characterize overall donepezil and concomitant utilization with β-blockers, yearly, in older New Zealanders. Deidentified data from the Pharmaceutical claims database and the National Minimum Dataset were obtained for 2011 to 2013 from the
Ndukwe, HC, Nishtala, PS
core   +1 more source

Considerations for Initiation and Maintenance of Foslevodopa/Foscarbidopa for Advanced Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri, Bruno Bergmans, Eric Freire‐Alvarez, Lucie Hopes, Drew S. Kern, Robert S. Kirsner, Giulia Lazzeri, Pedro Mendes‐Bastos, Noriko Nishikawa, Per Odin, Karolina Poplawska‐Domaszewicz, Rajesh Pahwa, Yuval Ramot, Klaus Seppi, Tobias Warnecke, Robert Wiggins, Megha B. Shah, Pavnit Kukreja, Bjoern Fritz, Koray Onuk, Stuart H. Isaacson   +20 more
wiley   +1 more source

Cognitive, Motor and Oculomotor Contributions to the Trail Making Test in Progressive Supranuclear Palsy

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by motor, oculomotor and cognitive impairments. Yet disentangling cognitive deficits from motor and oculomotor dysfunction remains a diagnostic and methodological challenge.
Indira Garcia‐Cordero, Mohsen Hadian, Juan Camilo Vargas‐Gonzalez, Marta Monteiro, David Gold, Abeer Khoja, Alonso Morales‐Rivero, Blas Couto, David Tang‐Wai, Susan Fox, Gabor G. Kovacs, Anthony E. Lang, Maria Carmela Tartaglia   +12 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Histological Protection by Donepezil Against Neurodegeneration Induced by Ischemia–Reperfusion in the Rat Retina

Journal of Pharmacological Sciences, 2010
Although a blockade of acetylcholine esterase has been reported to suppress neuronal cell death induced by exogenous glutamate and β-amyloid, information is still limited regarding the neuroprotective effects of the acetylcholine esterase inhibitor ...
Kenji Sakamoto, Kayo Ohki, Maki Saito, Tsutomu Nakahara, Kunio Ishii   +4 more
doaj   +1 more source

Emergency Departments Leading the Transformation of Alzheimer's and Dementia Care: Emergency Care Redesign

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Over 50% of persons living with dementia (PLWD) and their care partners (dyads) visit the emergency department (ED) every year. In the ED, healthcare professionals face complex challenges managing acute issues and symptoms of Alzheimer's disease and Alzheimer's disease–related dementias without provider training or in‐ED structures to ensure a
Afshana Hoque, Allison Cuthel, Corita R. Grudzen, Manish N. Shah, Abraham A. Brody, Jori E. Fleisher, Jennifer DiMascio‐Donohue, Katelyn McLain, Lin T. Tun, Julia Levine, Keith S. Goldfeld, Joshua Chodosh, ED‐LEAD Investigators, Lauren Abbate, Rebecca Anthopolos, Alicia Arbaje, Fernanda Bellolio, Jonathan Berkowitz, Andrea Blome, Erik Jonathan Blutinger, Justin Kenneth Brooten, Reed Caldwell, Christopher Caspers, Nathaniel Chin, Edward Cisek, Valerie Cotter, Jeremy Thomas Cushman, Dan David, Allison L. Ducharme‐Smith, Scott Dresden, Mary Ellen Dupont, Marie Carmelle Elie, Andra Farcas, Bucky Ferozan, Nicholas Genes, Cameron Gettel, Andrea Gilmore‐Bykovski, Elizabeth Goldberg, Scott Goldberg, Satheesh Gunaga, Heather Heaton, Courtney Jones, Maura Kennedy, Timmy Li, Joseph Miller, Brian Mittman, Kei Ouchi, Brian W Patterson, Jennifer Portz, Alex Quinones, Suzanne Ryer, Ashley Shreves, Michelle Simpson, Silas Smith, Payal Sud, Joe Suyama, Scotty Thomas, Victoria Vaughan Dickson, Ian Wittman, Nancy Wood   +59 more
wiley   +1 more source

Bridging the Gap Between the ED and Home: The Community Paramedic‐Led Transitions Intervention for Persons Living With Dementia

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT More than 6 million persons living with dementia (PLWD) in the United States rely on the emergency department (ED) for unscheduled care, with up to half discharged home after treatment. The ED‐to‐home transition poses significant challenges for PLWD and their care partners (referred to as “dyads”), contributing to high rates of ED revisits and
Meghan Jenkins Morales, Stephanie Ricketts, Corita R. Grudzen, Abraham A. Brody, Joshua Chodosh, Keith Goldfeld, Manish N. Shah, ED‐LEAD Investigators, Lauren Abbate, Rebecca Anthopolos, Alicia Arbaje, Fernanda Bellolio, Jonathan Berkowitz, Andrea Blome, Erik Jonathan Blutinger, Justin Kenneth Brooten, Reed Caldwell, Christopher Caspers, Nathaniel Chin, Edward Cisek, Valerie Cotter, Jeremy Thomas Cushman, Dan David, Allison L. Ducharme‐Smith, Scott Dresden, Mary Ellen Dupont, Marie Carmelle Elie, Andra Farcas, Bucky Ferozan, Jori Fleisher, Nicholas Genes, Cameron Gettel, Andrea Gilmore‐Bykovski, Scott Goldberg, Elizabeth Goldberg, Satheesh Gunaga, Heather Heaton, Courtney Jones, Maura Kennedy, Timmy Li, Joseph Miller, Brian Mittman, Kei Ouchi, Brian W. Patterson, Jennifer Portz, Alex Quinones, Ashley Shreves, Michelle Simpson, Silas Smith, Payal Sud, Joe Suyama, Scotty Thomas, Victoria Vaughan Dickson, Ian Wittman, Nancy Wood   +54 more
wiley   +1 more source

Burden and Risk Factors of CGM‐Detected Hypoglycemia in Older Adults With Type 2 Diabetes

Journal of the American Geriatrics Society, EarlyView.
Among older adults with diabetes using insulin or sulfonylureas, the median time spent in hypoglycemia was 3.4% and ~66% of participants exceeded the target of < 1% time with CGM glucose < 70 mg/dL. ABSTRACT Background Comprehensive data on the burden of biochemical hypoglycemia in older adults with type 2 diabetes are lacking.
Michael Fang, Natalie Rula Daya, Yein Jeon, Justin B. Echouffo‐Tcheugui, B. Gwen Windham, Scott Zeger, Elizabeth Selvin   +6 more
wiley   +1 more source