Results 31 to 40 of about 137,112 (292)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Optimization of Enzymatic Hydrolysis Conditions and Micromorphology of Bone Collagen Peptides from Donkey with Iron Chelating Ability

open access: yesLiang you shipin ke-ji, 2022
In order to make full use of donkey bone resources, a method was developed to hydrolyze donkey bone with protease to obtain donkey bone collagen peptide.
MAO Jia-min   +7 more
doaj   +1 more source

The ‘wonderful’ donkey – Of real and fabled donkeys

open access: yesHTS Teologiese Studies / Theological Studies, 2019
An ethological appreciation of the donkey has confirmed that it is a special and unique animal. The donkey is a well-adapted, sensitive, sociable, intelligent and notably loyal animal. Their so-called ‘stubbornness’ (dumbness) points rather to a species-specific intelligence to survive.
openaire   +4 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A Relapsed Donkey [PDF]

open access: yesNature, 1876
SOME years ago on one of the Lucknow roads I met a “Dhobi” (washerman) with some donkeys. I send you a picture of one of them, made by a native artist. It shows, I think, the relationship between the zebra and the donkey better than many which I have seen.
openaire   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Comment on Ssuna et al. Animal Welfare Guidelines for International Development Organisations in the Global South. Animals 2024, 14, 2012

open access: yesAnimals
International Development Organisations (IDOs) undertake critical work to improve the lives of people across the world, particularly in the Global South [...]
Jo Hockenhull   +4 more
doaj   +1 more source

Development of a Real-Time PCR Assay for the Detection of Donkey (Equus asinus) Meat in Meat Mixtures Treated under Different Processing Conditions

open access: yesFoods, 2020
In this study, a donkey-specific primer pair and probe were designed from mitochondrial cytochrome b gene for the detection of raw donkey meat and different processed meat mixtures.
Mi-Ju Kim   +5 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Quality of donkey bresaola

open access: yesItalian Journal of Animal Science, 2009
Nutritional and organoleptic properties were evaluated in bresaola of cow and don- key meat and, moreover, was made a comparison between these two products. The cured products were made from semitendinosus muscle taken from 8 female donkeys and 8 cows.
MARINO, ROSARIA MARIA TERESA   +4 more
openaire   +4 more sources

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