Results 181 to 190 of about 73,720 (258)

Silencing of the Metabolic Gene HKDC1 Is Associated With Aging and Neurodegeneration in Mice and Humans

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
Model showing decline in HKDC1 gene expression with aging. In a young cell, TFEB gets recruited to its binding sites on the HKDC1 promoter to upregulate HKDC1 expression, which interacts with mitochondria and stabilizes PINK1 to maintain mitochondrial health.
Zeenat Farooq   +8 more
wiley   +1 more source

Screening, optimization and characterization of exopolysaccharides produced by novel strains isolated from Moroccan raw donkey milk. [PDF]

open access: yesFood Chem X, 2022
Derdak R   +9 more
europepmc   +1 more source

AMUSE Livestock, version 2―Antimicrobial use in livestock production: A tool to harmonise data collection on knowledge, attitude and practices [PDF]

open access: yes, 2020
Alemu, Biruk   +11 more
core  

WDR72 Is Required for Urinary Acidification and Normal H+‐ATPase Activity in Intercalated Cells in Mice

open access: yesActa Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim Biallelic inactivating WDR72 variants are linked to distal renal tubular acidosis (dRTA), nephrocalcinosis, and amelogenesis imperfecta. The kidney shows high WDR72 expression; its precise localization and function remain unclear. WDR72 is a member of the WD40 repeat domain protein family—a large group of scaffold proteins involved in ...
Hannah Auwerx   +4 more
wiley   +1 more source

Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity

open access: yesBrain Pathology, Volume 36, Issue 2, March 2026.
Increased calponin‐3 expression correlates with astrocyte activation in epileptic mice, modulating adenosine metabolism regulators ADK and ENT1. Calponin‐3 overexpression increased susceptibility to epileptic seizures, while its downregulation reduces spontaneous recurrent seizures, identifying it as a potential therapeutic target for epilepsy ...
Lu Chen   +12 more
wiley   +1 more source

NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia [PDF]

open access: yes, 2017
Araki, Toshiyuki   +6 more
core   +2 more sources

Loanwords in Finnish Quiz [PDF]

open access: yes
A nine-part quiz that features words that have been borrowed into the Finnish language before the 20th century. The quiz helps students to learn to recognise loanwords. Students will also acquire new vocabulary and have fun.
Valijarvi, Riitta-Liisa
core  

Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells

open access: yesThe FEBS Journal, Volume 293, Issue 5, Page 1495-1515, March 2026.
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari   +6 more
wiley   +1 more source

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