Results 251 to 260 of about 135,445 (284)

NIPAL1 Drives a Metabolic‐Epigenetic Feedback Loop to Promote Lactate‐Mediated Immune Evasion in Esophageal Cancer

open access: yesAdvanced Science, EarlyView.
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen   +15 more
wiley   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

open access: yesAdvanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Clinical Impact of Supplementation with Pasteurized Donor Human Milk by High-Temperature Short-Time Method versus Holder Method in Extremely Low Birth Weight Infants: A Multicentre Randomized Controlled Trial. [PDF]

open access: yesNutrients
García-Lara NR   +13 more
europepmc   +1 more source

Microbiological Screening of Donor Human Milk

Breastfeeding Medicine, 2023
Mother's own milk is recognized as the optimal feeding not only for term but also for preterm infants. In addition to risk reduction for sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia, and retinopathy of prematurity in the early infancy, feeding preterm infants with mother's own milk is also associated with a better neurodevelopmental ...
Christine Schreiner   +2 more
openaire   +2 more sources

Human Donor Milk in Maternity

British Journal of Midwifery, 2023
Ines Salmoral and Denise McGuinness reflect on whether human donor milk should be made available for healthy term infants in the maternity setting
Ines Salmoral, Denise McGuinness
openaire   +1 more source

Characterization of Human Milk Donors

Journal of Human Lactation, 2007
The primary objective of this research was to create a detailed characterization of human milk donors, including descriptive information about demographics and lifestyle, involvement with the milk bank, reasons for donating, problems encountered while breastfeeding and pumping milk, barriers to donating milk, affective experiences, and personal values.
Richard, Osbaldiston, Leigh A, Mingle
openaire   +2 more sources

Immunomodulatory Constituents of Human Donor Milk

Breastfeeding Medicine, 2020
Mother's own human milk is the best nutrition for infants, especially preterm very-low-birth-weight (VLBW) (≤1,500 g) infants, because of its immune-modulatory constituents that strengthen the infant's host defense, provide protection against infections, and decrease the risk of necrotizing enterocolitis (NEC).
openaire   +2 more sources

Macronutrient content of donor human breast milk

Archives of Disease in Childhood - Fetal and Neonatal Edition, 2013
Background Nutritional analysis of donated human milk has been suggested as a means of optimising its use. Methods We analysed pooled, single donor milk samples using the MIRIS Human Milk Analyser to obtain values for fat, protein, lactose and ...
Andrew Ross, Cooper   +4 more
openaire   +2 more sources

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