Results 91 to 100 of about 577,472 (296)

Engaging Local Non-Governmental Organizations (NGOs) in the Response to HIV/AIDS. [PDF]

, 2005
During the past few years, a number of key donor programs have scaled up their global response to the crisis of HIV and AIDS. The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), the World Health Organization (WHO), the Joint United Nations ...
Cornman, Helen, Grimm, Curt D., Rana, Sujata   +2 more
core   +1 more source

Donor states in modulation-doped Si/SiGe heterostructures

, 2003
We present a unified approach for calculating the properties of shallow donors inside or outside heterostructure quantum wells. The method allows us to obtain not only the binding energies of all localized states of any symmetry, but also the energy ...
A. Blom, A. Blom, A. Blom, A. Blom, A. Onton, A. Onton, A. Pasquarello, A.A. Prokof’ev, A.A. Prokof’ev, B. Lambert, B.V. Shanabrook, B.V. Shanabrook, C. Herring, C. Jagannath, C. Priester, C. Sirtori, C.G. Van de Walle, D.D. Arnone, D.Y. Oberli, E. Goldys, E.R. Mueller, F. Capasso, F.J. Betancur, G. Bastard, G. Masini, H. Yaguchi, H.P. Wagner, I. N. Yassievich, I.V. Altukhov, J.A. Brum, J.P. Dismukes, J.P. Loehr, K. Jayakumar, K.-A. Chao, M. A. Odnoblyudov, M. Helm, M. Stopa, M.A. Odnoblyudov, M.M. Rieger, N. Binggeli, N.C. Jarosik, N.O. Lipari, R. Baron, R. Buczko, R.A. Faulkner, R.C. Miller, R.L. Greene, R.L. Greene, S. Fraizzoli, S. Glutsch, S. Pantelides, S.A. Lynch, S.T. Yen, S.V. Gastev, T.A. Perry, U. Fano, V.Y. Aleshkin, W. Kohn, W.T. Masselink   +58 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Geographical Allocation Pattern of Spanish Official Development Assistance [PDF]

The geographical allocation of Spanish aid has been little studied, despite the fact that it is unusually concentrated on middle-income countries. This paper sets out a model of Spanish ODA policy based on an integrated approach reflecting recipient ...
Sergio Tezanos Vazquez (ICEI and QEH)
core  

Selection effects in forensic science [PDF]

, 2005
In this report we consider the following question: does a forensic expert need to know exactly how the evidential material was selected? We set up a few simple models of situations in which the way evidence is selected may influence its value in court ...
Franx, Geert Jan, Hochs, Peter, Nuyens, Misja, Palla, Luigi, Quant, Corrie, Trapman, Pieter, van Gennip, Yves   +6 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Nonlinear effect of body mass index on postoperative survival following isolated heart transplantation

JHLT Open
Background: Guidelines regarding recipient's body mass index (BMI) for heart transplant are evolving with variable cutoffs depending on the country and institution.
Reid Dale, PhD, Nataliya Bahatyrevich, MD, MS, Matthew Leipzig, BSc, Maria Elizabeth Currie, MD, PhD   +3 more
doaj   +1 more source

Differential Evolution with Enhanced Abilities for Adaptation Applied to Heterogeneous Numerical Optimization [PDF]

, 2012
This article presents an exploration of Differential Evolution (DE) algorithm with enhanced adaptability. The main purpose of this study is to identify how this search method can cope with changes of the number of variables of a hard design test, unaided.
Lazarova, Mariya, Penev, Kalin
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source