Results 241 to 250 of about 8,564,356 (290)

The Presence of Donor-Specific Antibodies in Renal Transplantation

Transplantation Proceedings, 2012
Determining the presence of anti-HLA antibodies before transplantation is an important factor to prevent loss of function among renal transplantations. In addition, recent studies have shown that not only the pretransplantation existence of anti-HLA antibody but also posttransplantation donor-specific antibodies (DSA) and non-donor-specific antibodies ...
Kilicarslan-Ayna, T., TOZKIR, HİLMİ, Sezer, A., GÜRKAN, HAKAN, Sari, G., SAĞIROĞLU, GÖNÜL, Copuroglu, E., Tan, S., Sagiroglu, T.   +8 more
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Kidney transplant monitoring by anti donor specific antibodies

Transplant International, 1992
Donor-specific anti-HLA antibodies were studied by cytotoxicity crossmatching (CTXM) and flow cytometry crossmatching (FCXM) in 117 kidney transplant candidates; the same study was carried out in 33 cadaver-donor kidney recipients, during the first 3 post-transplant months, for which donor cells were available. Pre-transport evaluation showed that 82.9%
N Torlone, A Piazza, M Valeri, PI Monaco, L Provenzani, E Poggi, D Adorno, CU Casciani   +7 more
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Clinical relevance of circulating donor-specific HLA antibodies

Current Opinion in Organ Transplantation, 2010
For a long period of time complement-dependent cytotoxicity was the standard assay to demonstrate clinically relevant HLA antibodies in the serum of patients before transplantation. The introduction of more sensitive solid-phase assays to detect HLA antibodies had led to a lot of discussion on the clinical relevance of the presence of these antibodies ...
Claas, F.H.J., Frans HJ Claas
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Correlation between Luminex donor‐specific crossmatches and levels of donor‐specific antibodies in pretransplantation screening

Tissue Antigens, 2013
AbstractBefore kidney transplantation, recipients are routinely screened for preformed antibodies and prospective crossmatches. In this study, we compared prospective Luminex donor‐specific crossmatches (LumXm) with the levels of identified, donor‐specific antibodies (DSAs).
Guillaume, N., Mazouz, H., Piot, V., Presne, C., Westeel, P.‐f.   +4 more
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Donor-specific antibodies and liver transplantation

Human Immunology, 2016
In contrast to other types of organ transplantation, liver-transplant recipients used to be considered highly resistant to donor-specific antibodies (DSAs). Consequently, most transplant programs did not consider the presence of DSAs at transplantation or during the follow-up.
Arnaud, Del Bello, Nicolas, Congy-Jolivet, Marie, Danjoux, Fabrice, Muscari, Nassim, Kamar   +4 more
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Donor-specific antibodies in lung transplantation

Current Opinion in Organ Transplantation, 2020
Purpose of review The development of donor-specific antibodies (DSA) after lung transplantation has been recognized as an important risk factor for poor outcomes over the past 20 years. Recently, this has been a focus of intense research, and the purpose of this review is to summarize our current understanding of humoral ...
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Impact of donor-specific antibodies in reconstructive transplantation

Expert Review of Clinical Immunology, 2013
For many devastating injuries and tissue defects where conventional reconstruction is not possible, reconstructive transplantation such as hand and face transplantation has become a viable alternative. This novel approach allows for improved restoration of appearance, anatomy and function not feasible by other available treatment options.
Angelo A, Leto Barone, Zhaoli, Sun, Robert A, Montgomery, W P Andrew, Lee, Gerald, Brandacher   +4 more
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Increasing relevance of donor-specific antibodies in antibody-mediated rejection

Journal of Nephrology, 2012
One of the major concerns in organ transplantation is the early detection of humoral rejection, through improved diagnostic and prognostic biomarkers. Long-term survival of renal allografts is significantly lower in recipients developing donor-specific anti-HLA antibodies (DSAs) either pretransplant or posttransplant.
Zito A, Schena A, Grandaliano G, Schena F.P., GESUALDO, Loreto   +4 more
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Donor-specific antibodies in kidney deceased donor transplantation

Human Immunology, 2015
Aim Pre-sensitization against a broad array of HLA is associated with prolonged waiting times and inferior kidney allograft survival. Although the use of solid phase assay (SPA) for the detection and characterization of anti-HLA antibodies provides greater sensitivity than complement-dependent lymphocytotoxicity (CDC) assay, it often detects donor ...
Eric K. Ho, Xiuwei Tang, Li Lingzhi, Lloyd E. Ratner, George Vlad, Rodica E. Vasilescu   +5 more
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Donor-specific antibody and sensitized patients in intestinal transplantation

Current Opinion in Organ Transplantation, 2021
Purpose of review It has been well established that antibody to donor HLA pretransplant and the development of anti-human leukocyte antigen (HLA) antibodies posttransplant contribute to inferior graft survival outcomes. This article serves to review the current status of the management of pretransplant sensitized intestinal ...
Cal S, Matsumoto, Sandra, Rosen-Bronson
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