Results 81 to 90 of about 8,564,356 (290)

Preformed Donor-Specific HLA Antibodies in Living and Deceased Donor Transplantation [PDF]

Clinical Journal of the American Society of Nephrology, 2019
Background and objectives The prognostic value of preformed donor-specific HLA antibodies (DSA), which are only detectable by sensitive methods, remains controversial for kidney transplantation. Design, setting, participants, & measurements
Ziemann, Malte, Altermann, Wolfgang, Angert, Katharina, Arns, Wolfgang, Bachmann, Anette, Bakchoul, Tamam, Banas, Bernhard, von Borstel, Annette, Budde, Klemens, Ditt, Vanessa, Einecke, Gunilla, Eisenberger, Ute, Feldkamp, Thorsten, Görg, Siegfried, Guthoff, Martina, Habicht, Antje, Hallensleben, Michael, Heinemann, Falko M., Hessler, Nicole, Hugo, Christian, Kaufmann, Matthias, Kauke, Teresa, Koch, Martina, König, Inke R., Kurschat, Christine, Lehmann, Claudia, Marget, Matthias, Mühlfeld, Anja, Nitschke, Martin, Pego da Silva, Luiza, Quick, Carmen, Rahmel, Axel, Rath, Thomas, Reinke, Petra, Renders, Lutz, Sommer, Florian, Spriewald, Bernd, Staeck, Oliver, Stippel, Dirk, Süsal, Caner, Thiele, Bernhard, Zecher, Daniel, Lachmann, Nils   +42 more
openaire   +4 more sources

THE ROLE OF PRE-TRANSPLANT AND DE NOVO ALLOANTIBODIES IN KIDNEY TRANSPLANTATION

Вестник трансплантологии и искусственных органов, 2011
Kidney transplant recipients may have pre-transplant alloantibodies or develop de novo anti-HLA and non- HLA antibodies after transplantation. Although these antibodies may be donor-specific or non-donor-specific, their presence may increase the risk for
A. I. Sushkov, V. Y. Abramov, Y. G. Moysyuk   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition [PDF]

, 2013
The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodies ...
Ramos, Alejandra, Alexandre M. J. J. Bonvin (18079), David Lutje Hulsik, Verrips, C. Theo, Ying-ying Liu, Liu, Ying-ying, Battella, Simone, Jean-Pierre Simorre, C. Theo Verrips (200972), Miriam Hock, Miriam Hock (386536), Lucy Rutten (386540), Nika M. Strokappe (386532), Davis, David, Hinz, Andreas, Alejandra Ramos, Mohamed El Khattabi (386534), Bonvin, Alexandre M. J. J., Michael S Seaman, Rutten, Lucy, Alexandre M J J Bonvin, Simone Battella, Marlén M. I. Aasa-Chapman (208291), Pascal Poignard (244468), Sabin, Charles, Pascal Poignard, Seaman, Michael S., Anna Forsman Quigley, Pauline Macheboeuf, Seaman, Michael, Andreas Hinz (237046), Forsman Quigley, Anna, Anna Forsman Quigley (177474), Strokappe, Nika M, C Theo Verrips, Simorre, Jean-Pierre, Mohamed El Khattabi, Hulsik, David Lutje, Andreas Hinz, Winfried Weissenhorn (214542), McCoy, Laura E., Langedijk, Johannes P M, Johannes P. M. Langedijk (254439), Pauline Macheboeuf (386537), Charles Sabin, Marlén M I Aasa-Chapman, David Davis (190113), Robin A. Weiss (254468), Johannes P M Langedijk, Favier, Adrien, Lucy Rutten, Laura E. McCoy (386535), Adrien Favier (386539), Hock, Miriam, Alejandra Ramos (386538), Weiss, Robin A., Nika M Strokappe, David Lutje Hulsik (177480), Winfried Weissenhorn, Macheboeuf, Pauline, Lutje Hulsik, David, David Davis, Robin A Weiss, Aasa-Chapman, Marlén M. I., Strokappe, Nika M., Ying-ying Liu (386531), Weissenhorn, Winfried, Adrien Favier, Weiss, Robin A, Simone Battella (386533), Langedijk, Johannes P. M., Bonvin, Alexandre M J J, Michael S. Seaman (155998), Jean-Pierre Simorre (177519), El Khattabi, Mohamed, Seaman, Michael S, Aasa-Chapman, Marlén M I, Laura E McCoy, Poignard, Pascal, Verrips, C Theo, Charles Sabin (75940), Weissenhorn W, Poignard P, Hock M, McCoy LE, Simorre JP, Rutten L., Aasa-Chapman Marlén M. I., Hock Miriam, Davis David, Rutten Lucy, Macheboeuf P, El Khattabi M, Battella Simone, Hinz A, Forsman Quigley A, Weiss Robin A., Langedijk JP, Lutje Hulsik D, Liu YY, Aasa Chapman MM, Ramos Alejandra, Simorre Jean-Pierre, Verrips C. Theo, Ramos A, Liu Ying-ying, Sabin C, Favier A, Macheboeuf Pauline, Weiss RA, Weissenhorn Winfried, Poignard Pascal, Davis D, Langedijk Johannes P. M., Hinz Andreas, Bonvin Alexandre M. J. J., Seaman Michael S., El Khattabi Mohamed, Bonvin AM, Strokappe NM, Sabin Charles, Strokappe Nika M., Seaman MS, Lutje Hulsik David, McCoy Laura E., Verrips CT, Forsman Quigley Anna, Favier Adrien, Mccoy, Laura E   +128 more
core   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Characterisation of HLA-specific antibodies [PDF]

A successful kidney transplant is the best treatment for established renal failure, yet around 300 patients per annum are denied transplants because they have antibodies, most notably directed against donor HLA or ABO in their blood, which have the ...
Lowe, David Philip
core  

Successful Allogeneic Hematopoietic Stem Cell Transplantation from A 5/10 Mismatched Unrelated Donor in A Patient with Donor-Specific Anti-HLA Antibodies.

, 2018
Hematopoietic stem cell transplantation (HSCT) from a mismatched unrelated donor, an haploidentical donor or a cord blood unit (CBU) has become a widely aviable approach if patient lacks a matched related or unrelated donor.
Almeida S, Rovira M, Carreras E, Serra C, Cid J, Solano MT, Rosiñol L, Urbano A, Martínez C, Suárez-Lledó M, Marín P, Lozano M, Fernández-Avilés F, Suárez-Lledó, M, Martínez, C, Carreras, E, Fernández-Avilés, F, Almeida, S, Moreno, A, Solano, MT, Serra, C, Urbano, A, Lozano, M, Gutiérrez-García, G, Marín, P, Rosiñol, L, Cid, J, Rovira, M   +27 more
core   +1 more source

High‐dimensional flow cytometry reveals lymphocyte subset populations predictive of chronic lung allograft dysfunction

Clinical & Translational Immunology
Objectives Despite cellular and antibody‐mediated rejection being clinically relevant drivers of chronic lung allograft dysfunction (CLAD), there are few studies describing the T‐ and B‐cell dynamics inherent to such alloreactive responses.
Rohia Farighi, Steven Hiho, Thomas Ashhurst, Emily SJ Edwards, Lucy Sullivan, Menno C vanZelm, Greg Snell, Glen Westall, David M Tarlinton, Dimitra Zotos   +9 more
doaj   +1 more source

Assessment of heart transplant recipients survival based on ultrasound diagnostic methods and immunological screening of antibodies to leukocyte donor antigens

Российский кардиологический журнал, 2019
Aim. To create a mathematical model for predicting an assessment of the risk of antibody-mediated rejection (AMR) and analyze the survival of recipients with antibodies to leukocyte donor antigens.Material and methods. A single-center study was conducted
L. K. Tkhatl, T. V. Stavenchuk, A. A. Khalafyan, E. Kosmacheva, Irina Pashkova   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source