Results 91 to 100 of about 506,450 (362)
Advanced Healthcare Materials, EarlyView.A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin +15 more
wiley +1 more source
Molecular Communication-Based Intelligent Dopamine Rate Modulator for Parkinson's Disease Treatment [PDF]
Parkinson's disease (PD) is a progressive neurodegenerative disease, and it is caused by the loss of dopaminergic neurons in the basal ganglia (BG). Currently, there is no definite cure for PD, and available treatments mainly aim to alleviate its symptoms.
arxiv +1 more source
Reward and adversity processing circuits, their competition and interactions with dopamine and serotonin signaling [PDF]
, 2013 We propose that dACC, AI and caudolateral OFC(clOFC) project to lateral habenula (LHb) and D2 loop of ventral striatum (VS), forming a functional adversity processing circuit, directed towards inhibitory avoidance and self-control. This circuit learns what is bad or harmful to us and predicts risks, to stop us from going/moving for bad or suboptimal ...
arxiv +1 more source
Advanced Healthcare Materials, EarlyView.An injectable polydopamine‐based nanohybrid hydrogel integrates controlled low‐temperature photothermal therapy with potent antibacterial efficacy against MRSA while promoting robust bone regeneration. The hydrogel's composite design triggers HSP70 expression, facilitating osteogenesis and efficient bone formation.
Fang Yang +13 more
wiley +1 more source
GABAergic-like dopamine synapses in the brain
Cell Reports, 2023 Summary: Dopamine synapses play a crucial role in volitional movement and reward-related behaviors, while dysfunction of dopamine synapses causes various psychiatric and neurological disorders.
Hyun-Jin Kim +12 more
doaj
High level modeling of tonic dopamine mechanisms in striatal neurons [PDF]
arXiv, 2007 The extant versions of many basal ganglia models use a `gating' model of dopamine function which enhances input to D1 receptor units and attenuates input to D2 receptor units. There is evidence that this model is unsatisfactory because (a) there are not sufficient dopaminergic synapses to gate all input and (b) dopamine's main effect is likely to be on
arxiv
Advanced Healthcare Materials, EarlyView.This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey +5 more
wiley +1 more source
Annals of Medicine, 1996 The DA hypothesis of schizophrenia is one of the oldest biological hypotheses of schizophrenia with many revised versions. However, it is unlikely that any single neurotransmitter hypothesis is able to explain the biological basis of such a highly heterogenous disorder as schizophrenia in a satisfactory way.
Jarmo Hietala, Erkka Syvälahti
openaire +2 more sources
Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose
Advanced Materials, EarlyView.Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew +2 more
wiley +1 more source
A computational model revealing the effect of dopamine on action selection [PDF]
arXiv, 2015 In order to reveal the effect of nigrostriatal dopamine system on action selection, first a computational model of the cortex-basal ganglia-thalamus loop is proposed and based on this model a simple compound model realizing the Stroop effect is established.
arxiv