Results 91 to 100 of about 826,720 (382)
Midbrain dopamine neurons signal aversion in a reward-context-dependent manner
eLife, 2016 Dopamine is thought to regulate learning from appetitive and aversive events. Here we examined how optogenetically-identified dopamine neurons in the lateral ventral tegmental area of mice respond to aversive events in different conditions. In low reward
Hideyuki Matsumoto +3 more
doaj +1 more source
Nature Reviews Neuroscience, 2019 Midbrain dopamine signals are widely thought to report reward prediction errors that drive learning in the basal ganglia. However, dopamine has also been implicated in various probabilistic computations, such as encoding uncertainty and controlling exploration.
Samuel J. Gershman, Naoshige Uchida
openaire +4 more sources
Dopamine and Dopamine-Related Ligands Can Bind Not Only to Dopamine Receptors
Life, 2022 The dopaminergic system is one of the most important neurotransmitter systems in the central nervous system (CNS). It acts mainly by activation of the D1-like receptor family at the target cell. Additionally, fine-tuning of the signal is achieved via pre-synaptic modulation by the D2-like receptor family.
openaire +3 more sources
Advanced Functional Materials, EarlyView.A unique 2D bionanozyme, engineered from a single amino acid and copper ions, demonstrates peroxidase‐mimicking catalytic activity. This efficient and simple bionanozyme allows for ultrasensitive, equipment‐free visual detection of key biomarkers in both test and real samples, meeting the WHO‐REASSURE standards for practical diagnostic applications ...
Subrat Vishwakarma +5 more
wiley +1 more source
Frontiers in Psychiatry, 2011 Accumbal glycine modulates basal and ethanol-induced dopamine levels in the nucleus accumbens (nAc) as well as voluntary ethanol consumption. Also, systemic administration of the glycine transporter-1 inhibitor Org25935 elevates dopamine levels in nAc ...
Helga eHöifödt Lidö +4 more
doaj +1 more source
GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson\u27s Disease. [PDF]
, 2019 While GM1 may interact with α-synuclein in vitro to inhibit aggregation, the ability of GM1 to protect against α-synuclein toxicity in vivo has not been investigated.
Aras, Radha +5 more
core +1 more source
Interactions of dopamine and dopamine hydrochloride with ethanol [PDF]
Journal of Molecular Liquids, 2016 Abstract Cyclic voltammetry (CV), density functional theory (DFT) calculations, and atoms in molecules (AIM) analyses were performed to investigate the hydrogen bonding in dopamine-ethanol and dopamine hydrochloride-ethanol mixtures. CV results show that the anodic/cathodic peak potential of dopamine hydrochloride in ethanol is influenced by the ...
Huiting Ma +6 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.Biopolymers are sustainable, biodegradable alternatives to petroleum‐based plastics for food packaging. Its adoption is often limited by poor mechanical strength, barrier properties, and improved thermal stability through the incorporation of nanofillers.
Himakshi Baishya +2 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2019 Background: The dopaminergic system has been associated with the progression of Alzheimer's disease. But previous studies found inconsistent results regarding the relationship between Alzheimer's disease and dopamine when looking at dopamine receptor ...
Xiongfeng Pan +9 more
doaj +1 more source
Deficient reinforcement learning in medial frontal cortex as a model of dopamine-related motivational deficits in ADHD [PDF]
, 2013 A
Barke, Edmund +3 more
core +2 more sources