Results 81 to 90 of about 360,985 (311)

Carborane Analog of Dopamine D3 Receptor Antagonist Eticlopride [PDF]

, 2016
Dopamine, a small neurotransmitter released by the brain, plays a major role in the body's reward and motivation systems. Dopamine interacts with a class of G-Protein coupled receptors-- D1R through D5R-- to propagate or mitigate the dopamine signaling ...
Ashbrook, Caleb
core  

Synergistic Solar Interfacial Evaporation and Photocatalysis Enabled by a Hierarchical Porous Hydrogel Reactor

Advanced Functional Materials, EarlyView.
A tree‐inspired hydrogel interfacial reactor couples solar evaporation with photocatalysis for simultaneous desalination and waste water treatment. The bilayer design achieves 2.14 kg·m−2·h−1 evaporation rate with 79% dye degradation under one sun, demonstrating that photothermal heating and evaporation induced pollutant enrichment create a self ...
Yan Zhao, Xiaolong Ma, Zihong Wu, Muhammad Amjad, Dongsheng Wen   +4 more
wiley   +1 more source

Dopamine Response to Unexpected Aversive Outcomes Drives the Return of Extinguished Fear

Brain Sciences
Background/Objectives: Dopamine is well known for its role in reward learning, where phasic activity encodes prediction errors and supports the formation of cue–outcome associations.
Bhumiben P. Patel, Jennifer Tat, Oyku Dinckol, Noah Harris Wenger, Aryanna Copling, Munir Gunes Kutlu   +5 more
doaj   +1 more source

A role for accumbal glycine receptors in modulation of dopamine release by the glycine transporter-1 inhibitor Org25935

Frontiers in Psychiatry, 2011
Accumbal glycine modulates basal and ethanol-induced dopamine levels in the nucleus accumbens (nAc) as well as voluntary ethanol consumption. Also, systemic administration of the glycine transporter-1 inhibitor Org25935 elevates dopamine levels in nAc ...
Helga eHöifödt Lidö, Mia eEricson, Hugh eMarston, Bo eSöderpalm, Bo eSöderpalm   +4 more
doaj   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis

Frontiers in Aging Neuroscience, 2019
Background: The dopaminergic system has been associated with the progression of Alzheimer's disease. But previous studies found inconsistent results regarding the relationship between Alzheimer's disease and dopamine when looking at dopamine receptor ...
Xiongfeng Pan, Atipatsa C. Kaminga, Atipatsa C. Kaminga, Shi Wu Wen, Shi Wu Wen, Xinyin Wu, Xinyin Wu, Kwabena Acheampong, Kwabena Acheampong, Aizhong Liu   +9 more
doaj   +1 more source

Enzyme‐Loaded Fe3+‐Modified Polydopamine Microparticles: Bioreactor Systems for Operating Biocatalytic Cascades, Enantioselective Transformations and Sensor Applications

Advanced Functional Materials, EarlyView.
Enzyme‐loaded Fe3+‐modified polydopamine microparticles (Fe3+‐PD) act as hybrid biocatalytic frameworks demonstrating NADH peroxidase‐mimic catalytic activities, operation of biocatalytic cascades in confined media, and enantioselective oxidation of D/L‐DOPA. ABSTRACT We report on the synthesis of Fe3+‐modified porous polydopamine microparticles acting
Liubing Kong, Sérgio R. S. Veloso, Yichen Han, Jianghe Zhao, Vitaly Gutkin, Ofir Tirosh, Itamar Willner   +6 more
wiley   +1 more source

A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice [PDF]

, 2010
BACKGROUND: Parkinson's disease (PD), the second most frequent neurodegenerative disorder at old age, can be caused by elevated expression or the A53T missense mutation of the presynaptic protein alpha-synuclein (SNCA). PD is characterized pathologically
Liss Birgit, Paolo Calabresi, Auburger Georg, Silke Nuber, Javier Fernández-Ruiz, Lastres-Becker, Isabel, Double Kay L., Auburger, Georg, Lüddens Hartmut, Nuber Silke, Fernández-Ruiz, Javier, Fernández-Ruiz Javier, Gispert, Suzana, Schlaudraff Falk, Nuber, Silke, García-Arencibia Moisés, García-Arencibia, Moisés, Manfred Gerlach, Gerlach, Manfred, Double, Kay L., Kay L. Double, Alexander Kurz, Tantucci Michela, Bonin Michael, Bockhart, Vanessa, Gispert Suzana, Calabresi, Paolo, Lüddens, Hartmut, Moisés García-Arencibia, Tozzi Alessandro, Michael Bonin, Michela Tantucci, Schlaudraff, Falk, Hartmut Lüddens, Lastres-Becker Isabel, Isabel Lastres-Becker, Tantucci, Michela, Birgit Liss, Wüllner Ullrich, Ullrich Wüllner, Kurz Alexander, Vanessa Bockhart, Liss, Birgit, Falk Schlaudraff, Kurz, Alexander, Suzana Gispert, Bonin, Michael, Calabresi Paolo, Wüllner, Ullrich, Georg Auburger, Tozzi, Alessandro, Kay L Double, Alessandro Tozzi, Gerlach Manfred, Bockhart Vanessa   +54 more
core   +1 more source

Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV

Journal of Neuroinflammation
The catecholamine neurotransmitter dopamine is classically known for regulation of central nervous system (CNS) functions such as reward, movement, and cognition. Increasing evidence also indicates that dopamine regulates critical functions in peripheral
Stephanie M. Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A. Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C. M. Schlachetzki, Howard S. Fox, Peter J. Gaskill   +16 more
doaj   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source