Results 181 to 190 of about 835,082 (382)

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

Science, 2018
Tommaso Patriarchi, J. Cho, Katharina Merten, Mark Howe, Aaron Marley, Wei-Hong Xiong, R. Folk, G. Broussard, Ruqiang Liang, M. Jang, H. Zhong, D. Dombeck, M. von Zastrow, A. Nimmerjahn, V. Gradinaru, John T. Williams, L. Tian   +16 more
semanticscholar   +1 more source

Recent Advances in Variable‐Stiffness Robotic Systems Enabled by Phase‐Change Materials

Advanced Robotics Research, EarlyView.
Phase‐change materials (PCMs), such as shape memory alloys, hydrogels, shape memory polymers, liquid crystal elastomers, and low‐melting‐point alloys, are driving advancements in stiffness‐tunable robotic systems across a wide range of applications. This review highlights recent progress in PCM‐enabled robotics, focusing on their underlying mechanisms,
Sukrit Gaira, Liao Wu, Ming Li, Priyank Kumar, Xiaopeng Li, Shi‐Yang Tang   +5 more
wiley   +1 more source

Magnetic Field Driven Microrobot Based on Hydrogels

Advanced Robotics Research, EarlyView.
Hydrogel‐based magnetic microrobots synergize remote magnetic control with the biocompatibility of flexible hydrogels, emerging as promising tools for minimally invasive biomedicine. This enables remotely controllable, untethered navigation within complex biological microenvironments.
Juncai Song, Yubing Guo
wiley   +1 more source

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

Plasmalogen Augmentation Reverses Striatal Dopamine Loss in MPTP Mice

, 2016
Edith Miville-Godbout, Mélanie Bourque, Marc Morissette, Sara Al-Sweidi, Tara Smith, Asuka Mochizuki, Vijitha Senanayake, Dushmanthi Jayasinghe, Li Wang, Dayan B. Goodenowe, Thérèse Di Paolo   +10 more
openalex   +2 more sources

Integrated Flexible Zwitterionic Electrochemical Sensor Platform for Real‐Time Salivary Glucose Quantification

Advanced Sensor Research, EarlyView.
A flexible electrochemical sensor platform can enable continuous, real‐time monitoring of salivary glucose for applications confined to spaces such as the oral cavity. Surface modifications with Prussian blue, chitosan, and zwitterionic polymers enhance sensitivity, selectivity, and antiadherent performance.
Stephanie Klinghammer, Gylxhane Kastrati, Leif Riemenschneider, Michael Geiger‐Hoffmann, Luis Antonio Panes‐Ruiz, Johan Peter Woelber, Christian Hannig, Gianaurelio Cuniberti, Torsten Sterzenbach   +8 more
wiley   +1 more source

Rats classified as low or high cocaine locomotor responders: A unique model involving striatal dopamine transporters that predicts cocaine addiction-like behaviors

, 2013
Dorothy J. Yamamoto, Anna M. Nelson, Bruce H. Mandt, Gaynor A. Larson, Jacki M. Rorabaugh, Christopher M.C. Ng, Kelsey Barcomb, Toni L. Richards, Richard M. Allen, Nancy R. Zahniser   +9 more
openalex   +1 more source

The dopamine hypothesis of schizophrenia: version III--the final common pathway.

Schizophrenia bulletin, 2009
O. Howes, S. Kapur
semanticscholar   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

Cortico‐Striatal‐Midbrain Circuit Dysregulation Underlying MK‐801 Induced Impulsivity and the Ameliorative Effects of SEP

Advanced Science, EarlyView.
Impulsivity is a symptom across multiple psychiatric disorders, yet its neural basis remains elusive. This study shows that the NMDAR antagonist MK‐801 elevates dopamine release and disrupts neuronal selectivity in the nucleus accumbens, leading to impulsive behavior.
Xueru Wang, Qinyu Li, Zijie Li, Xuejiao Wang, Hui Yuan, Pingting Yang, Ling Qin   +6 more
wiley   +1 more source