Results 171 to 180 of about 359,850 (311)

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Aptamer-Functionalized SWCNT Optical Sensors for Selective and Robust Dopamine Detection in Physiological Media. [PDF]

ACS Appl Nano Mater
Stefoni MC, Yafai H, Ryan AK, Israel A, Williams RM.   +4 more
europepmc   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Involvement of mu-opiate receptors in ethanol-induced accumbal dopamine response

, 2003
textThe goal of this dissertation was to investigate the role of µ-opiate receptors in the regulation of ethanol-induced accumbal dopamine release using µ-opiate receptor knockout mice.
Tang, Man Amanda, 1972-
core  

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, EarlyView.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

The dynamics of synaptic dopamine clearance: relevance to alcohol use disorder

Impulse: The Premier Undergraduate Neuroscience Journal
Alcohol misuse is a leading cause of preventable death, yet the neurochemical changes governing its addictive properties remain elusive. Ethanol, the psychoactive component of alcoholic beverages, interacts with many neurotransmitter systems, including ...
Karina Piotrowska, Elaine Fitches
doaj  

Correction: Vitamin A deficiency induces sex-specific reward processing alterations through a dysregulation of the mesolimbic dopamine transmission in mice. [PDF]

Neuropsychopharmacology
Couty P, Yung S, Dulapt I, Berger L, Santoro A, Hardt L, Petitbon A, Ducrocq F, Walle R, Catanese J, Alfos S, Helbling JC, Angelo MF, Sabran C, Borel P, Ferreira G, Bosch-Bouju C, Trifilieff P, Touyarot K.   +18 more
europepmc   +1 more source

Dopamine D-3 receptors regulate GABA(A) receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens

, 2006
The dopamine D-3 receptor, which is highly enriched in nucleus accumbens (NAc), has been suggested to play an important role in reinforcement and reward.
Kittler, JT, Chen, GJ, Yan, Z, Moss, SJ
core  

Versatile DNA‐Functionalized Biohybrid Hydrogel Platforms for Electrothermally Activated On‐Demand Payload Release

Advanced Science, EarlyView.
A DNA‐functionalized biohybrid hydrogel is developed by integrating Cu‐mediated nucleic acid microflowers into a thermoresponsive matrix, enabling electrothermally triggered, on‐demand payload release. The platform offers spatiotemporally controllable therapeutic delivery with promising applications in precision oncology, neural regulation, and chronic
Mengqiu Sun, Zhenshuai Tang, Jia Zhang, Rui Song, Wei Luo, Juan Huang, Jincheng Zeng, Zhen He, Hao Zhang   +8 more
wiley   +1 more source