Results 21 to 30 of about 786,774 (402)

Adsorption properties of dopamine derivatives using carbon nanotubes: A first-principles study [PDF]

open access: yesApplied Surface Science, Volume 501, 31 January 2020, 144249, 2020
Detecting dopamine is of great biological importance because the molecule plays many roles in the human body. For instance, the lack of dopamine release is the cause of Parkinson's disease. Although many researchers have carried out experiments on dopamine detection using carbon nanotubes (CNTs), there are only a few theoretical studies on this topic ...
arxiv   +1 more source

Dopamine and glutamate in schizophrenia: biology, symptoms and treatment

open access: yesWorld Psychiatry, 2020
Glutamate and dopamine systems play distinct roles in terms of neuronal signalling, yet both have been proposed to contribute significantly to the pathophysiology of schizophrenia.
R. McCutcheon, J. Krystal, O. Howes
semanticscholar   +1 more source

The neural basis of human error processing: reinforcement learning, dopamine, and the error-related negativity.

open access: yesPsychology Review, 2002
The authors present a unified account of 2 neural systems concerned with the development and expression of adaptive behaviors: a mesencephalic dopamine system for reinforcement learning and a "generic" error-processing system associated with the anterior
Clay B. Holroyd, M. Coles
semanticscholar   +1 more source

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1988
The effect of various drugs on the extracellular concentration of dopamine in two terminal dopaminergic areas, the nucleus accumbens septi (a limbic area) and the dorsal caudate nucleus (a subcortical motor area), was studied in freely moving rats by ...
G. Dichiara, A. Imperato
semanticscholar   +1 more source

Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice.

open access: yesPLoS ONE, 2013
Dopamine regulates the psychomotor stimulant activities of amphetamine-like substances in the brain. The effects of dopamine are mediated through five known dopamine receptor subtypes in mammals.
Seiji Hayashizaki   +8 more
doaj   +1 more source

Effects of dopamine D2 receptor partial agonist antipsychotic aripiprazole on dopamine synthesis in human brain measured by PET with L-[β-11C]DOPA. [PDF]

open access: yesPLoS ONE, 2012
Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists.
Hiroshi Ito   +8 more
doaj   +1 more source

Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

open access: yeseLife, 2017
Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber fluorometry in mice.
William Menegas   +3 more
doaj   +1 more source

Loss of angiotensin II receptor expression in dopamine neurons in Parkinson’s disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation [PDF]

open access: yes, 2015
In rodent models of Parkinsons disease (PD), dopamine neuron loss is accompanied by increased expression of angiotensin II (AngII), its type 1 receptor (AT1), and NADPH oxidase (Nox) in the nigral dopamine neurons and microglia.
Aboud, O   +6 more
core   +2 more sources

Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release

open access: yeseLife, 2020
Dopamine powerfully controls neural circuits through neuromodulation. In the vertebrate striatum, dopamine adjusts cellular functions to regulate behaviors across broad time scales, but how the dopamine secretory system is built to support fast and slow ...
Aditi Banerjee   +4 more
doaj   +1 more source

M₅ muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. [PDF]

open access: yesPLoS ONE, 2011
Opiates, like other addictive drugs, elevate forebrain dopamine levels and are thought to do so mainly by inhibiting GABA neurons near the ventral tegmental area (VTA), in turn leading to a disinhibition of dopamine neurons.
Stephan Steidl   +3 more
doaj   +1 more source

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