Results 11 to 20 of about 360,985 (311)

Dopamine-Regulated Plasticity in MoO₃ Synaptic Transistors [PDF]

, 2023
Field-effect transistor-based biosensors have gained increasing interest due to their reactive surface to external stimuli and the adaptive feedback required for advanced sensing platforms in biohybrid neural interfaces.
Duc Minh Tran (15059720), Chanyong Hwang (1467142), Jong Wan Son (1561339), Bae Ho Park (1560988), Tae-Seong Ju (8200758)   +4 more
core   +1 more source

Neuroprotection by dopamine agonists [PDF]

, 1994
Research on Parkinson's disease has led to new hypotheses concerning the mechanisms of neurodegeneration and to the development of neuroprotective agents.
Rausch, W. D., Naumann, M., Riederer, P., Oestreicher, E., Lange, Klaus W., Gsell, W.   +5 more
core   +1 more source

Stimulus representation and the timing of reward-prediction errors in models of the dopamine system [PDF]

, 2008
The phasic firing of dopamine neurons has been theorized to encode a reward-prediction error as formalized by the temporal-difference (TD) algorithm in reinforcement learning.
Sutton, Richard S., Kehoe, E. James, Ludvig, Elliot Andrew   +2 more
core   +1 more source

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits

Neurobiology of Disease, 2015
The dopamine transporter is a key protein responsible for regulating dopamine homeostasis. Its function is to transport dopamine from the extracellular space into the presynaptic neuron. Studies have suggested that accumulation of dopamine in the cytosol
S.T. Masoud, L.M. Vecchio, Y. Bergeron, M.M. Hossain, L.T. Nguyen, M.K. Bermejo, B. Kile, T.D. Sotnikova, W.B. Siesser, R.R. Gainetdinov, R.M. Wightman, M.G. Caron, J.R. Richardson, G.W. Miller, A.J. Ramsey, M. Cyr, A. Salahpour   +16 more
doaj   +1 more source

Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

eLife, 2017
Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber fluorometry in mice.
William Menegas, Benedicte M Babayan, Naoshige Uchida, Mitsuko Watabe-Uchida   +3 more
doaj   +1 more source

Dopamine inactivation efficacy related to functional DAT1 and COMT variants influences motor response evaluation [PDF]

, 2012
BACKGROUND: Dopamine plays an important role in orienting, response anticipation and movement evaluation. Thus, we examined the influence of functional variants related to dopamine inactivation in the dopamine transporter (DAT1) and catechol-O ...
Laucht, Manfred (Prof. Dr.), Rellum Thomas, Thomas Rellum, Resch, Franz, Stephan Bender, Brandeis, Daniel, Banaschewski, Tobias, Laucht Manfred, Bender, Stephan, Rietschel, Marcella, Jennen-Steinmetz, Christine, Freitag, Christine M., Treutlein, Jens, Jens Treutlein, Rellum, Thomas, Daniel Brandeis, Brandeis Daniel, Tobias Banaschewski, Jennen-Steinmetz Christine, Christine Freitag, Bender Stephan, Banaschewski Tobias, Manfred Laucht, Freitag, Christine, Franz Resch, Rietschel Marcella, Marcella Rietschel, Resch Franz, Christine Jennen-Steinmetz, Laucht, Manfred, Treutlein Jens, Freitag Christine   +31 more
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seanfw/dopamine-dist-wm: Dopamine working memory model code [PDF]

, 2021
Example Jupyter notebooks to reproduce the main figures in Froudist-Walsh, Sean, Daniel P. Bliss, Xingyu Ding, Lucija Jankovic-Rapan, Meiqi Niu, Kenneth Knoblauch, Karl Zilles, Henry Kennedy, Nicola Palomero-Gallagher, and Xiao-Jing Wang.
seanfw
core   +1 more source

Effects of dopamine D2 receptor partial agonist antipsychotic aripiprazole on dopamine synthesis in human brain measured by PET with L-[β-11C]DOPA. [PDF]

PLoS ONE, 2012
Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists.
Hiroshi Ito, Harumasa Takano, Ryosuke Arakawa, Hidehiko Takahashi, Fumitoshi Kodaka, Keisuke Takahata, Tsuyoshi Nogami, Masayuki Suzuki, Tetsuya Suhara   +8 more
doaj   +1 more source

Conformation of dopamine at the dopamine receptor. [PDF]

Proceedings of the National Academy of Sciences, 1978
Tritiated dopamine was used to label the dopamine receptor in membranes isolated from the rat corpus striatum. Scatchard analysis of displacement of [3H]dopamine by nonradioactive dopamine indicated the presence of two binding sites. The similarities in affinity, capacity, and drug specificity of the high-affinity site in the striatal membranes from ...
H L, Komiskey, J F, Bossart, D D, Miller, P N, Patil   +3 more
openaire   +2 more sources

Disrupted dopamine transmission and the emergence of exaggerated beta oscillations in subthalamic nucleus and cerebral cortex [PDF]

, 2008
In the subthalamic nucleus (STN) of Parkinson’s disease (PD) patients, a pronounced synchronization of oscillatory activity at beta frequencies (15–30 Hz) accompanies movement difficulties.
Sharott, A, Brown, Peter, Bolam, JP, Pogosyan, A, Magill, PJ, Brown, P, Mallet, N, Csicsvari, J   +7 more
core   +1 more source