Results 21 to 30 of about 17,756 (194)

Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice.

PLoS ONE, 2013
Dopamine regulates the psychomotor stimulant activities of amphetamine-like substances in the brain. The effects of dopamine are mediated through five known dopamine receptor subtypes in mammals.
Seiji Hayashizaki, Shinobu Hirai, Yumi Ito, Yoshiko Honda, Yosefu Arime, Ichiro Sora, Haruo Okado, Tohru Kodama, Masahiko Takada   +8 more
doaj   +1 more source

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits

Neurobiology of Disease, 2015
The dopamine transporter is a key protein responsible for regulating dopamine homeostasis. Its function is to transport dopamine from the extracellular space into the presynaptic neuron. Studies have suggested that accumulation of dopamine in the cytosol
S.T. Masoud, L.M. Vecchio, Y. Bergeron, M.M. Hossain, L.T. Nguyen, M.K. Bermejo, B. Kile, T.D. Sotnikova, W.B. Siesser, R.R. Gainetdinov, R.M. Wightman, M.G. Caron, J.R. Richardson, G.W. Miller, A.J. Ramsey, M. Cyr, A. Salahpour   +16 more
doaj   +1 more source

Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

eLife, 2017
Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber fluorometry in mice.
William Menegas, Benedicte M Babayan, Naoshige Uchida, Mitsuko Watabe-Uchida   +3 more
doaj   +1 more source

Effects of dopamine D2 receptor partial agonist antipsychotic aripiprazole on dopamine synthesis in human brain measured by PET with L-[β-11C]DOPA. [PDF]

PLoS ONE, 2012
Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists.
Hiroshi Ito, Harumasa Takano, Ryosuke Arakawa, Hidehiko Takahashi, Fumitoshi Kodaka, Keisuke Takahata, Tsuyoshi Nogami, Masayuki Suzuki, Tetsuya Suhara   +8 more
doaj   +1 more source

Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release

eLife, 2020
Dopamine powerfully controls neural circuits through neuromodulation. In the vertebrate striatum, dopamine adjusts cellular functions to regulate behaviors across broad time scales, but how the dopamine secretory system is built to support fast and slow ...
Aditi Banerjee, Jinoh Lee, Paulina Nemcova, Changliang Liu, Pascal S Kaeser   +4 more
doaj   +1 more source

Nucleus Accumbens and Dopamine-Mediated Turning Behavior of the Rat: Role of Accumbal Non-dopaminergic Receptors

Journal of Pharmacological Sciences, 2012
Accumbal dopamine plays an important role in physiological responses and diseases such as schizophrenia, Parkinson’s disease, and depression. Since the nucleus accumbens contains different neurotransmitters, it is important to know how they interact with
Hiroko Ikeda, Junzo Kamei, Noriaki Koshikawa, Alexander R. Cools   +3 more
doaj   +1 more source

M₅ muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. [PDF]

PLoS ONE, 2011
Opiates, like other addictive drugs, elevate forebrain dopamine levels and are thought to do so mainly by inhibiting GABA neurons near the ventral tegmental area (VTA), in turn leading to a disinhibition of dopamine neurons.
Stephan Steidl, Anthony D Miller, Charles D Blaha, John S Yeomans   +3 more
doaj   +1 more source

Normal Uterus and Ovary in the Indonesian Population: A Comprehensive Analysis

Women's Health Reports
Objective: This research seeks to establish comprehensive baseline data on the normal anatomical features of the uterus and ovaries in a cohort of healthy Indonesian subjects. Methods: This research was a retrospective study employing 500 ultrasonography
Andi Darma Putra, Aldi Tamara Rahman, Lasmini Syariatin, Naufal Syafiq Darmawan, Dian Catur Permatasari   +4 more
doaj   +1 more source

Endometrial thickness evaluation with ultrasonography assessment among normal and endometrial cancer across multi-ethnic Indonesian women

Frontiers in Reproductive Health
IntroductionEndometrial thickness is a crucial indicator for reproductive health evaluation and initial detection of abnormalities. This study aims to comprehensively characterize and evaluate the endometrium in normal and cancer of Indonesian women ...
Andi Darma Putra, Andi Darma Putra, Aldi Tamara Rahman, Aldi Tamara Rahman, Naufal Syafiq Darmawan, Naufal Syafiq Darmawan, Lasmini Syariatin, Lasmini Syariatin, Firda Puspita, Firda Puspita   +9 more
doaj   +1 more source

Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons

European Journal of Histochemistry, 2014
Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structure of the adult rat arcuate-median eminence complex, and determine the distribution of the dopamine D1 and D2 receptor immunoreactivities therein ...
W. Romero-Fernandez, D.O. Borroto-Escuela, V. Vargas-Barroso, M. Narváez, M. Di Palma, L.F. Agnati, J. Larriva Sahd, K. Fuxe   +7 more
doaj   +1 more source