Results 21 to 30 of about 563,934 (275)

Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence. [PDF]

open access: yes, 2016
BackgroundCigarette smoking induces dopamine release in the striatum, and smoking- or nicotine-induced ventral striatal dopamine release is correlated with nicotine dependence.
London, Edythe D   +2 more
core   +2 more sources

Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice.

open access: yesPLoS ONE, 2013
Dopamine regulates the psychomotor stimulant activities of amphetamine-like substances in the brain. The effects of dopamine are mediated through five known dopamine receptor subtypes in mammals.
Seiji Hayashizaki   +8 more
doaj   +1 more source

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits

open access: yesNeurobiology of Disease, 2015
The dopamine transporter is a key protein responsible for regulating dopamine homeostasis. Its function is to transport dopamine from the extracellular space into the presynaptic neuron. Studies have suggested that accumulation of dopamine in the cytosol
S.T. Masoud   +16 more
doaj   +1 more source

Cholinergic modulation of dopamine overflow in the rat neostriatum: A fast cyclic voltammetric study in vitro [PDF]

open access: yes, 1994
Stimulus-evoked dopamine overflow in rat neostriatal slices was determined using fast cyclic voltammetry. The dopamine efflux induced by intrastriatal stimulation increased with stimulus intensity and was found to be enhanced by more than 100% upon ...
Kudernatsch, Martina, Sutor, Bernd
core   +1 more source

Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

open access: yeseLife, 2017
Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber fluorometry in mice.
William Menegas   +3 more
doaj   +1 more source

Effects of dopamine D2 receptor partial agonist antipsychotic aripiprazole on dopamine synthesis in human brain measured by PET with L-[β-11C]DOPA. [PDF]

open access: yesPLoS ONE, 2012
Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists.
Hiroshi Ito   +8 more
doaj   +1 more source

Midbrain Dopamine Neurons Signal Belief in Choice Accuracy during a Perceptual Decision [PDF]

open access: yes, 2017
Central to the organization of behavior is the ability to predict the values of outcomes to guide choices. The accuracy of such predictions is honed by a teaching signal that indicates how incorrect a prediction was (“reward prediction error,” RPE).
Kepec, A.   +4 more
core   +2 more sources

Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release

open access: yeseLife, 2020
Dopamine powerfully controls neural circuits through neuromodulation. In the vertebrate striatum, dopamine adjusts cellular functions to regulate behaviors across broad time scales, but how the dopamine secretory system is built to support fast and slow ...
Aditi Banerjee   +4 more
doaj   +1 more source

Monoaminergic modulation of photoreception in ascidian:evidence for a proto-hypothalamo-retinal territory [PDF]

open access: yes, 2012
Background : The retina of craniates/vertebrates has been proposed to derive from a photoreceptor prosencephalic territory in ancestral chordates, but the evolutionary origin of the different cell types making the retina is disputed.
Brown, Euan R   +7 more
core   +5 more sources

M₅ muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. [PDF]

open access: yesPLoS ONE, 2011
Opiates, like other addictive drugs, elevate forebrain dopamine levels and are thought to do so mainly by inhibiting GABA neurons near the ventral tegmental area (VTA), in turn leading to a disinhibition of dopamine neurons.
Stephan Steidl   +3 more
doaj   +1 more source

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