Results 41 to 50 of about 563,934 (275)
Testosterone induces molecular changes in dopamine signaling pathway molecules in the adolescent male rat nigrostriatal pathway. [PDF]
PLoS ONE, 2014 Adolescent males have an increased risk of developing schizophrenia, implicating testosterone in the precipitation of dopamine-related psychopathology.
Tertia D Purves-Tyson +5 more
doaj +1 more source
Putting Desire on a Budget: Dopamine and Energy Expenditure, Reconciling Reward and Resources
Frontiers in Integrative Neuroscience, 2012 Accumulating evidence indicates integration of dopamine function with metabolic signals, highlighting a potential role for dopamine in energy balance, frequently construed as modulating reward in response to homeostatic state.
Jeff A Beeler +3 more
doaj +1 more source
eLife, 2017 LRRK2 mutations produce end-stage Parkinson’s disease (PD) with reduced nigrostriatal dopamine, whereas, asymptomatic carriers have increased dopamine turnover and altered brain connectivity.
Mattia Volta +14 more
doaj +1 more source
The dopaminergic midbrain participates in human episodic memory formation: Evidence from genetic imaging [PDF]
, 2006 Recent data from animal studies raise the possibility that dopaminergic neuromodulation promotes the encoding of novel stimuli. We investigated a possible role for the dopaminergic midbrain in human episodic memory by measuring how polymorphisms in ...
Bernstein, HG +9 more
core +1 more source
Effects of cocaethylene on dopamine and serotonin synthesis in Long–Evans and Sprague–Dawley brains [PDF]
, 1998 We examined the behavioral and neurochemical effects of cocaethylene treatment in Long–Evans ( LE). and Sprague–Dawley (SD) rats. Cocaethylene-induced behaviors were significantly less in LE rats.
Baumann, Dr. M.H. +3 more
core +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Neurobiology of Disease, 2015 Dopamine function is disturbed in Parkinson's disease (PD), but whether and how release of dopamine from surviving neurons is altered has long been debated.
Katie A. Jennings +2 more
doaj +1 more source
Mechanisms Regulating the Association of Protein Phosphatase 1 with Spinophilin and Neurabin [PDF]
, 2018 Protein phosphorylation is a key mediator of signal transduction, allowing for dynamic regulation of substrate activity. Whereas protein kinases obtain substrate specificity by targeting specific amino acid sequences, serine/threonine phosphatase ...
Baucum, Anthony J., II +6 more
core +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2014 Dopamine mediates diverse functions such as motivation, reward, attention, learning/memory and sleep/arousal. Recent studies using model organisms including the fruit fly, have elucidated various physiological functions of dopamine, and identified ...
Taro eUeno +3 more
doaj +1 more source