Results 41 to 50 of about 259,710 (99)

GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABAA receptors

Cell Reports
Summary: Striatal dopamine axons co-release dopamine and gamma-aminobutyric acid (GABA), using GABA provided by uptake via GABA transporter-1 (GAT1). Functions of GABA co-release are poorly understood.
Jyoti C. Patel, Ang D. Sherpa, Riccardo Melani, Paul Witkovsky, Madeline R. Wiseman, Brian O’Neill, Chiye Aoki, Nicolas X. Tritsch, Margaret E. Rice   +8 more
doaj   +1 more source

Molecular simulation study of RNA/dopamine complex dynamics at varying concentrations

Scientific Reports
The interaction between dopamine and RNA structures holds significant potential for understanding neurotransmitter-driven RNA modulation and biosensor design.
Armen H. Poghosyan, Yevgeni S. Mamasakhlisov, Marine A. Parsadanyan, Mariam A. Shahinyan, Zvart H. Movsisyan, Poghos O. Vardevanyan   +5 more
doaj   +1 more source

A Role for Adenosine A1 Receptors in GABA and NMDA-Receptor Mediated Modulation of Dopamine Release: Studies Using Fast Cyclic Voltammetry

Sensors, 2008
In the striatum many neurotransmitters including GABA, glutamate, acetylcholine, dopamine, nitric oxide and adenosine interact to regulate synaptic transmission. Dopamine release in the striatum is regulated by a number of pre- and postsynaptic receptors
Carmel O’Neill, John J. O’Connor   +1 more
doaj   +1 more source

Whole-Brain Confocal Imaging Provides an Accurate Global View of the Nigral Dopamine System

Diagnostics
Clinicopathological studies and the effectiveness of dopaminergic replacement therapy establish that dopamine loss is the key pathology causing motor symptoms in Parkinson’s disease. The dopamine neurons that are impaired in Parkinson’s disease reside in
Fu-Ming Zhou
doaj   +1 more source

The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue.

Frontiers in Psychiatry, 2014
: Dopamine is an inhibitory neurotransmitter involved in the pathology of schizophrenia.The revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and prefrontal brain regions exist in schizophrenia. However, recent research has
Ralf eBrisch, Arthur eSaniotis, Rainer eWolf, Hendrik eBielau, Hans-Gert eBernstein, Johann eSteiner, Bernhard eBogerts, Katharina A Braun, Zbigniew eJankowski, Jaliya eKumaratilake, Maciej eHenneberg, Tomasz eGos   +11 more
doaj   +1 more source

Differential dopaminergic modulation of the antennal lobe of Drosophila melanogaster

Communications Biology
Olfaction plays a key role in the ability of organisms to monitor their ever-changing chemical environment. Dopamine is a key modulator of the mammalian and insect nervous systems, including the fruit fly Drosophila melanogaster.
Gavriel Avishai, Moshe Parnas
doaj   +1 more source

Devaluing memories of reward: a case for dopamine

Communications Biology
Midbrain dopamine cells encode differences in predictive and expected value to support learning through reward prediction error. Recent findings have questioned whether reward prediction error can fully account for dopamine function and suggest a more ...
Benjamin R. Fry, Nicolette Russell, Victoria Fex, Bing Mo, Nathan Pence, Joseph A. Beatty, Fredric P. Manfredsson, Brandon A. Toth, Christian R. Burgess, Samuel Gershman, Alexander W. Johnson   +10 more
doaj   +1 more source

Dopamine Enhances Healthspan and Locomotor Performance via Antioxidant Defense in Silkworms, Bombyx mori

Insects
The impact of dopamine on aging is complex and context-dependent. This study systematically investigated the effects of dopamine levels on the lifespan and behavior of the silkworm moth by employing genetic mutants of the dopamine synthesis/metabolic ...
Songzhen He, Wenhao Yang, Hai Hu, Fangyin Dai, Xiaoling Tong   +4 more
doaj   +1 more source

Disruption of Dopamine Homeostasis by Psychostimulants. [PDF]

Mol Neurobiol
Torres J, Bredenkamp C, Vazquez A, Chivero ET.   +3 more
europepmc   +1 more source

The potential of neuromelanin-sensitive MRI in psychiatric disorders. [PDF]

Neurosci Appl
Neutelings E, van de Giessen E, de Haan L, van der Pluijm M.   +3 more
europepmc   +1 more source