Results 41 to 50 of about 826,720 (382)

Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons

European Journal of Histochemistry, 2014
Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structure of the adult rat arcuate-median eminence complex, and determine the distribution of the dopamine D1 and D2 receptor immunoreactivities therein ...
W. Romero-Fernandez, D.O. Borroto-Escuela, V. Vargas-Barroso, M. Narváez, M. Di Palma, L.F. Agnati, J. Larriva Sahd, K. Fuxe   +7 more
doaj   +1 more source

Corticosterone Acts in the Nucleus Accumbens to Enhance Dopamine Signaling and Potentiate Reinstatement of Cocaine Seeking [PDF]

, 2013
Stressful life events are important contributors to relapse in recovering cocaine addicts, but the mechanisms by which they influence motivational systems are poorly understood.
Baker, David A., Ebben, Amanda L., Gasser, Paul J., Graf, Evan N., Hill, Jonathan E., Mantsch, John R., McReynolds, Jayme R., Robble, Mykel A., Vranjkovic, Oliver, Wheeler, Daniel S., Wheeler, Robert A.   +10 more
core   +2 more sources

Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit [PDF]

, 2009
The striatum, the principal input structure of the basal ganglia, is crucial to both motor control and learning. It receives convergent input from all over the neocortex, hippocampal formation, amygdala and thalamus, and is the primary recipient of ...
Alexander, Bar-Gad, Bauswein, Beiser, Belluardo, Berke, Berke, Bevan, Blackwell, Bolam, Bracci, Bracci, Brown, Burke, Buzsaki, Carrillo-Reid, Centonze, Cho, Czubayko, Dawson, Djurfeldt, Ferro, Frank, Fukai, Galan, Galarreta, Galvan, Gerfen, Glynn, Gonon, Gorelova, Groenewegen, Gurney, Humphries, Humphries, Humphries, Hurd, Ingham, Izhikevich, Izhikevich, Jaeger, Jahr, Kawaguchi, Kawaguchi, Kevin Gurney, Kirik, Kita, Koos, Koos, Kubota, Kwok, Lago-Fernandez, Mallet, Mark D. Humphries, Markram, McGeorge, Miller, Moyer, Newman, Newman, Nisenbaum, Nishikawa, Oorschot, O’Donnell, Pennartz, Plenz, Redgrave, Ric Wood, Richtand, Sandstrom, Schultz, Schwarting, Smith, Sullivan, Surmeier, Tang, Tateno, Taverna, Tepper, Traub, Tseng, Tunstall, Turner, Venton, Wang, Watts, Whishaw, Wickens, Wickens, Wilson, Yin, Zheng, Zhou   +92 more
core   +1 more source

Putting Desire on a Budget: Dopamine and Energy Expenditure, Reconciling Reward and Resources

Frontiers in Integrative Neuroscience, 2012
Accumulating evidence indicates integration of dopamine function with metabolic signals, highlighting a potential role for dopamine in energy balance, frequently construed as modulating reward in response to homeostatic state.
Jeff A Beeler, Cristianne R.M. Frazier, Xiaoxi eZhuang, Xiaoxi eZhuang   +3 more
doaj   +1 more source

GABAergic-like dopamine synapses in the brain

Cell Reports, 2023
Summary: Dopamine synapses play a crucial role in volitional movement and reward-related behaviors, while dysfunction of dopamine synapses causes various psychiatric and neurological disorders.
Hyun-Jin Kim, Byungjae Hwang, Maria Reva, Jieun Lee, Byeong Eun Lee, Youngeun Lee, Eun Jeong Cho, Minseok Jeong, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Jung-Hoon Park, Jae-Ick Kim   +12 more
doaj   +1 more source

The Dopaminergic Midbrain Encodes the Expected Certainty about Desired Outcomes [PDF]

, 2014
Dopamine plays a key role in learning; however, its exact function in decision making and choice remains unclear. Recently, we proposed a generic model based on active (Bayesian) inference wherein dopamine encodes the precision of beliefs about optimal ...
Dolan, Ray, FitzGerald, Thomas H B, Friston, Karl, Mathys, Christoph, Schwartenbeck, Philipp   +4 more
core   +2 more sources

Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice

eLife, 2017
LRRK2 mutations produce end-stage Parkinson’s disease (PD) with reduced nigrostriatal dopamine, whereas, asymptomatic carriers have increased dopamine turnover and altered brain connectivity.
Mattia Volta, Dayne A Beccano-Kelly, Sarah A Paschall, Stefano Cataldi, Sarah E MacIsaac, Naila Kuhlmann, Chelsie A Kadgien, Igor Tatarnikov, Jesse Fox, Jaskaran Khinda, Emma Mitchell, Sabrina Bergeron, Heather Melrose, Matthew J Farrer, Austen J Milnerwood   +14 more
doaj   +1 more source

Neuronal and psychological underpinnings of pathological gambling [PDF]

, 2014
Like in the case of drugs, gambling hijacks reward circuits in a brain which is not prepared to receive such intense stimulation. Dopamine is normally released in response to reward and uncertainty in order to allow animals to stay alive in their ...
Anselme, Bryan F. Singer, Clark, Goudriaan, Kalkhoven, Lawrence, Li, Linnet, Mike J. F. Robinson, Paglieri, Patrick Anselme, Paul Vezina, Porchet, Potenza, Singer, Tedford, van den Bos, Zack, Zack   +18 more
core   +3 more sources

The impact of a parkinsonian lesion on dynamic striatal dopamine transmission depends on nicotinic receptor activation

Neurobiology of Disease, 2015
Dopamine function is disturbed in Parkinson's disease (PD), but whether and how release of dopamine from surviving neurons is altered has long been debated.
Katie A. Jennings, Nicola J. Platt, Stephanie J. Cragg   +2 more
doaj   +1 more source

Milnacipran affects mouse impulsive, aggressive, and depressive-like behaviors in a distinct dose-dependent manner [PDF]

, 2017
Serotonin/noradrenaline reuptake inhibitors (SNRIs) are widely used for the treatment for major depressive disorder, but these drugs induce several side effects including increased aggression and impulsivity, which are risk factors for substance abuse ...
Ohmura, Yu, Tsutsui-Kimura, Iku, Yoshida, Takayuki, Yoshioka, Mitsuhiro   +3 more
core   +2 more sources