Results 21 to 30 of about 554,589 (315)

Clinical guidelines ‘Hyperprolactinemia’ (draft)

open access: yesОжирение и метаболизм, 2023
Hyperprolactinemia is a persistent excess of the blood serum prolactin. The syndrome contains various symptoms, the most characteristic is a violation of the reproductive system.
I. I. Dedov   +15 more
doaj   +1 more source

Revisiting the Medical Management of Parkinson's Disease: Levodopa versus Dopamine Agonist

open access: yesCurrent Neuropharmacology, 2016
The optimal treatment strategy for Parkinson's disease has been debated for decades. The introduction of levodopa (LD) treatment is frequently delayed because of theoretical concerns about its toxicity or the risk of drug-induced motor complications ...
Jinglin Zhang, L. Tan
semanticscholar   +1 more source

Rapid quantitative pharmacodynamic imaging by a novel method: theory, simulation testing and proof of principle [PDF]

open access: yesPeerJ 1:e117, 2013, 2013
Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines pharmacokinetic-pharmacodynamic modeling, repeated small doses of a challenge drug over a short time scale, and functional imaging
arxiv   +1 more source

Lower PRDM2 expression is associated with dopamine-agonist resistance and tumor recurrence in prolactinomas

open access: yesBMC Cancer, 2015
Dopamine agonists (DAs) are the first-line treatment for prolactinomas, which account for 25–30% of functioning pituitary adenomas, and bromocriptine (BRC) is the only commercially available DAs in China. However, tumors are resistant to therapy in 5–18%
Hua Gao   +9 more
semanticscholar   +1 more source

The partial dopamine D2 receptor agonist aripiprazole is associated with weight gain in adolescent anorexia nervosa

open access: yesInternational Journal of Eating Disorders, 2017
OBJECTIVE Finding medication to support treatment of anorexia nervosa has been difficult. Neuroscience-based approaches may help in this effort. Recent brain imaging studies in adults and adolescents with anorexia nervosa suggest that dopamine-related ...
G. Frank   +5 more
semanticscholar   +1 more source

Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor

open access: yesFrontiers in Pharmacology, 2022
Nicotine induces kinetic tremor, which resembles pharmacological features of essential tremors, via activating the inferior olive (IO) neurons. Since nicotine is known to enhance dopamine release by stimulating α4β2 and/or α6 nACh receptors, we examined ...
Masaki Kato   +4 more
doaj   +1 more source

Cannabidiol is a partial agonist at dopamine D2High receptors, predicting its antipsychotic clinical dose

open access: yesTranslational Psychiatry, 2016
Although all current antipsychotics act by interfering with the action of dopamine at dopamine D2 receptors, two recent reports showed that 800 to 1000 mg of cannabidiol per day alleviated the signs and symptoms of schizophrenia, although cannabidiol is ...
P. Seeman
semanticscholar   +1 more source

Enhancement in dopamine reduces generous behaviour in women.

open access: yesPLoS ONE, 2019
Generosity is a human behavior common in social contexts. However, humans are not equally generous to everyone alike. Instead, generosity decreases as a function of social distance, an effect called social discounting.
Sergio Oroz Artigas   +6 more
doaj   +1 more source

Aripiprazole-induced hyperprolactinemia in a young female with delusional disorder

open access: yesIndian Journal of Psychological Medicine, 2016
Hyperprolactinemia is a common adverse effect of antipsychotic medication. Switching over to aripiprazole or adjunctive aripiprazole has been advocated for optimal management of antipsychotic-induced hyperprolactinemia.
Sam Padamadan Joseph
doaj   +1 more source

Impulse control disorders in patients with dopamine agonist‐treated prolactinomas and nonfunctioning pituitary adenomas: a case–control study

open access: yesClinical Endocrinology, 2014
We aimed to assess the prevalence of impulse control disorders (ICDs) in patients with prolactin‐secreting adenomas treated with dopamine agonists (DAs), to identify associated factors and to compare it with a group of patients with nonfunctioning ...
I. Bancos   +5 more
semanticscholar   +1 more source

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