Results 41 to 50 of about 118,448 (336)
Neuropsychopharmacology Reports, 2020 Aims The United States of America is currently in an opioid epidemic. Heroin remains the most lethal opioid option with its death rate increasing by over 500% in the last decade.
Dominic P. Isaacs +5 more
doaj +1 more source
Discriminating depression, physical and social anhedonia by neurotransmitter related challenge tests [PDF]
, 2016 The aim of this study was to investigate, if anhedonia, a salient component of depression, shows similar response patterns to neurotransmitter challenge tests as depression, and if the two questionnaire based components Physical (PA) and Social (SA ...
Hennig, Juergen, Netter, Petra
core +2 more sources
The History and Pharmacology of Dopamine Agonists [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1984 ABSTRACTThe recognition of the dopaminergic properties of some ergot derivatives has initiated new therapeutical approaches in endocrinology as well as in neurology. The pharmacological characterization of the different ergot derivatives during the last decade has largely improved our understanding of central dopaminergic systems. Their development has
openaire +4 more sources
Activities of bone morphogenetic proteins in prolactin regulation by somatostatin analogs in rat pituitary GH3 cells [PDF]
, 2011 Involvement of the pituitary BMP system in the modulation of prolactin (PRL) secretion regulated by somatostatin analogs, including octreotide (OCT) and pasireotide (SOM230), and a dopamine agonist, bromocriptine (BRC), was examined in GH3 cells.
Inagaki, Kenichi +8 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail +3 more
wiley +1 more source
Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants [PDF]
, 2014 Within the nucleus accumbens (NAc), synaptic GABAA receptors (GABAARs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine.
Belelli, D +8 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra +7 more
wiley +1 more source
DOPAMINE AND THE BIOLOGY OF CREATIVITY: LESSONS FROM PARKINSON’S DISEASE
Frontiers in Neurology, 2014 BACKGROUND: Parkinson’s disease (PD) is characterized by reduced flexibility, conceptualization and visuo-spatial abilities. Although these are essential to creativity, case studies show emergence of creativity during PD.
Eugénie eLhommée +13 more
doaj +1 more source
Voltage-Dependent Dopamine Potency at D1-Like Dopamine Receptors
Frontiers in Pharmacology, 2020 In recent years, transmembrane voltage has been found to modify agonist potencies at several G protein-coupled receptors (GPCRs). Whereas the voltage sensitivities of the Gαi/o-coupled dopamine D2-like receptors (D2R, D3R, D4R) have previously been ...
Richard Ågren +3 more
doaj +1 more source
Heteroreceptor complexes and their allosteric receptor-receptor interactions in the central nervous system. Focus on examples from Dopamine D2 and Serotonin 5-HT1a receptors [PDF]
, 2018 GPCR interacting proteins (specially β- arrestin) and their receptor-protein interactions are also covered but their interactions with the allosteric receptor-receptor interactions in heteroreceptor complexes remain to be elucidated.
Corrales Ferro, Fidel
core +1 more source