Results 41 to 50 of about 862,104 (211)

Efficacy of dopamine antagonists in stimulating ovulation and spermiation of Caspian kutum (Rutilus frisii) under controlled conditions

Journal of the World Aquaculture Society
The present study compared the effectiveness of dopamine antagonists and commercial hormonal agents containing GnRH analogs combined with dopamine antagonists for inducing ovulation and spermiation in Caspian kutum (Rutilus frisii) spawners.
Erfan Akbari Nargesi, Dariusz Kucharczyk, Danial Gorouhi, Joanna Nowosad, Behrooz Heidari   +4 more
doaj   +1 more source

No difference in frontal cortical activity during an executive functioning task after acute doses of aripiprazole and haloperidol

Frontiers in Human Neuroscience, 2015
Background: Aripiprazole is an atypical antipsychotic drug that is characterized by partial dopamine D2 receptor agonism. Its pharmacodynamic profile is proposed to be beneficial in the treatment of cognitive impairment, which is prevalent in psychotic ...
Ingeborg eBolstad, Ingeborg eBolstad, Ole A Andreassen, Ole A Andreassen, Inge R Groote, Beathe eHaatveit, Beathe eHaatveit, Andres eServer, Jimmy eJensen, Jimmy eJensen   +9 more
doaj   +1 more source

Dopamine receptor antagonists.

Annals of palliative medicine, 2015
Intractable nausea and/or vomiting is a serious and significant clinical dilemma that may greatly detract from quality of life. One of the first classes of antiemetic agents used as well as one of the commonest classes of antiemetic agents used is that of the dopamine receptor antagonists.
Howard S, Smith, Lorrain R, Cox, Benjamin R, Smith   +2 more
openaire   +1 more source

D2 dopamine receptor subtype-mediated hyperactivity and amphetamine responses in a model of ADHD

Neurobiology of Disease, 2010
Low doses of psychostimulants produce beneficial behavioral effects in ADHD patients but the mechanisms underlying the response are not understood. Here we use the hyperactive mouse mutant coloboma to identify D2-like dopamine receptor subtypes that ...
Xueliang Fan, Ming Xu, Ellen J. Hess
doaj   +1 more source

Dopamine antagonist antipsychotics in diverted forensic populations

CNS Spectrums, 2019
In community settings, negative symptoms and cognitive deficits are the primary barriers to independent living, stable relationships, and employment for individuals suffering from schizophrenia-spectrum disorders. In contrast, however, positive psychotic symptoms (e.g., command hallucinations and persecutory delusions) often drive behavior which serves
Michael A. Cummings, George J. Proctor, Ai-Li W. Arias   +2 more
openaire   +2 more sources

Dopamine D2 antagonist-induced striatal Nur77 expression requires activation of mGlu5 receptors by cortical afferents

Frontiers in Pharmacology, 2012
Dopamine D2 receptor antagonists modulate gene transcription in the striatum. However, the molecular mechanism underlying this effect remains elusive. Here we used the expression of Nur77, a transcription factor of the orphan nuclear receptor family, as ...
Jérôme eMaheux, Michel eSt-Hilaire, David eVoyer, Emanuele eTirotta, Emiliana eBorrelli, Claude eRouillard, Pierre-Paul eRompré, Daniel eLévesque   +7 more
doaj   +1 more source

Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia

Frontiers in Pharmacology, 2020
Dopamine receptors are widely distributed within the brain where they play critical modulator roles on motor functions, motivation and drive, as well as cognition.
Jean Claude Martel, Silvia Gatti McArthur   +1 more
doaj   +1 more source

Quantification of the interaction forces between dengue virus and dopamine type-2 receptor using optical tweezers

Virology Journal
Background Dengue virus (DENV) causes the most significant mosquito-borne viral disease with a wide spectrum of clinical manifestation, including neurological symptoms associated with lethal dengue diseases.
Jane C. Arifin, Bo-Ying Tsai, Chun-Yu Chen, Li-Wei Chu, Yi-Ling Lin, Chau-Hwang Lee, Arthur Chiou, Yueh-Hsin Ping   +7 more
doaj   +1 more source

Activation of D1/5 Dopamine Receptors in the Dorsal Medial Prefrontal Cortex Promotes Incubated-Like Aversive Responses

Frontiers in Behavioral Neuroscience, 2017
It is well established that neurons of the mammalian medial prefrontal cortex (mPFC) modulate different behavioral outputs, including several memory types.
Fernando Castillo Díaz, Cecilia P. Kramar, Micaela A. Hernandez, Jorge H. Medina, Jorge H. Medina   +4 more
doaj   +1 more source

D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD

Neurobiology of Disease, 2007
The mechanisms underlying the effects of psychostimulants in attention deficit hyperactivity disorder (ADHD) are not well understood, but indirect evidence implicates D2 dopamine receptors. Here we dissect the components of dopaminergic neurotransmission
Xueliang Fan, Ellen J. Hess
doaj   +1 more source