Results 1 to 10 of about 156,081 (291)

KLHL12 Promotes Non-Lysine Ubiquitination of the Dopamine Receptors D4.2 and D4.4, but Not of the ADHD-Associated D4.7 Variant. [PDF]

PLoS ONE, 2015
DOPAMINE D4 RECEPTOR POLYMORPHISM:The dopamine D4 receptor has an important polymorphism in its third intracellular loop that is intensively studied and has been associated with several abnormal conditions, among others, attention deficit hyperactivity ...
Kamila Skieterska, Pieter Rondou, Béatrice Lintermans, Kathleen Van Craenenbroeck   +3 more
doaj   +1 more source

Modulation of Neuron and Astrocyte Dopamine Receptors via Receptor–Receptor Interactions

Pharmaceuticals, 2023
Dopamine neurotransmission plays critical roles in regulating complex cognitive and behavioral processes including reward, motivation, reinforcement learning, and movement.
Diego Guidolin, Cinzia Tortorella, Manuela Marcoli, Chiara Cervetto, Raffaele De Caro, Guido Maura, Luigi F. Agnati   +6 more
doaj   +1 more source

Dopamine receptor D2 regulates GLUA1-containing AMPA receptor trafficking and central sensitization through the PI3K signaling pathway in a male rat model of chronic migraine

The Journal of Headache and Pain, 2022
Background The pathogenesis of chronic migraine remains unresolved. Recent studies have affirmed the contribution of GLUA1-containing AMPA receptors to chronic migraine.
Wei Zhang, Ming Lei, Qianwen Wen, Dunke Zhang, Guangcheng Qin, Jiying Zhou, Lixue Chen   +6 more
doaj   +1 more source

Role of Dopaminergic and Cannabinoidergic Receptors on Ghrelin-Induced Hypophagia in 5-Day-Old Broiler Chicken [PDF]

Archives of Razi Institute, 2021
The present study aimed to identify the role of dopaminergic and cannabinoidergic systems in the ghrelin-induced hypophagia among meat-type chickens.
R Farrokhi, V Babapour, M Zendehdel, A Asghari, H Gilanpour   +4 more
doaj   +1 more source

Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy

Frontiers in Cardiovascular Medicine, 2022
BackgroundPrevious studies suggested involvement of non-ß-adrenoceptors in the pathogenesis of Takotsubo cardiomyopathy (TTC). This study was designed to explore possible roles and underlying mechanisms of dopamine D1/D5 receptor coupled signaling in ...
Mengying Huang, Zhen Yang, Yingrui Li, Huan Lan, Lukas Cyganek, Lukas Cyganek, Goekhan Yuecel, Goekhan Yuecel, Goekhan Yuecel, Siegfried Lang, Siegfried Lang, Siegfried Lang, Karen Bieback, Ibrahim El-Battrawy, Ibrahim El-Battrawy, Ibrahim El-Battrawy, Xiaobo Zhou, Xiaobo Zhou, Xiaobo Zhou, Xiaobo Zhou, Martin Borggrefe, Martin Borggrefe, Martin Borggrefe, Ibrahim Akin, Ibrahim Akin, Ibrahim Akin   +25 more
doaj   +1 more source

Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice.

PLoS ONE, 2013
Dopamine regulates the psychomotor stimulant activities of amphetamine-like substances in the brain. The effects of dopamine are mediated through five known dopamine receptor subtypes in mammals.
Seiji Hayashizaki, Shinobu Hirai, Yumi Ito, Yoshiko Honda, Yosefu Arime, Ichiro Sora, Haruo Okado, Tohru Kodama, Masahiko Takada   +8 more
doaj   +1 more source

Antipsychotic Induced Dopamine Receptor Supersensitivity and It’s Clinical Implications

Jurnal Psikiatri Surabaya, 2022
Background : Schizophrenia is a serious mental disorder that requires multi-modal and continuous treatment, mainly with antipsychotic. Along with the increasing life expectancy of schizophrenic patients, various problems due to prolonged blocking of ...
Riko Lazuardi, Khairina Rina, Dianasari
doaj   +1 more source

Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis

Frontiers in Aging Neuroscience, 2019
Background: The dopaminergic system has been associated with the progression of Alzheimer's disease. But previous studies found inconsistent results regarding the relationship between Alzheimer's disease and dopamine when looking at dopamine receptor ...
Xiongfeng Pan, Atipatsa C. Kaminga, Atipatsa C. Kaminga, Shi Wu Wen, Shi Wu Wen, Xinyin Wu, Xinyin Wu, Kwabena Acheampong, Kwabena Acheampong, Aizhong Liu   +9 more
doaj   +1 more source

Knockout of Dopamine D3 Receptor Gene Blocked Methamphetamine-Induced Distinct Changes of Dopaminergic and Glutamatergic Synapse in the Nucleus Accumbens Shell of Mice

Frontiers in Cellular Neuroscience, 2022
Structural plasticity changes in the brain are thought to underlie, at least partially, drug-induced persistent changes in behavior. Our previous study reported that increased synaptic density in the nucleus accumbens shell (NAcsh) correlates with and ...
Shuai Wang, Shuai Wang, Ming Li, Ming Li, Linlan Su, Linlan Su, Yu Wang, Yu Wang, Dongliang Ma, Hongyan Wang, Hongyan Wang, Jie Zhu, Jie Zhu, Teng Chen, Teng Chen   +14 more
doaj   +1 more source

Dopamine D1 and D2 receptor immunoreactivities in the arcuate-median eminence complex and their link to the tubero-infundibular dopamine neurons

European Journal of Histochemistry, 2014
Dopamine D1 and D2 receptor immunohistochemistry and Golgi techniques were used to study the structure of the adult rat arcuate-median eminence complex, and determine the distribution of the dopamine D1 and D2 receptor immunoreactivities therein ...
W. Romero-Fernandez, D.O. Borroto-Escuela, V. Vargas-Barroso, M. Narváez, M. Di Palma, L.F. Agnati, J. Larriva Sahd, K. Fuxe   +7 more
doaj   +1 more source