Results 121 to 130 of about 156,081 (291)

DOPAMINE RECEPTOR BLOCKING ACTIVITY OF SULPIRIDE IN THE CENTRAL NERVOUS SYSTEM

, 1977
Fumio Honda, Yoshihiko Satoh, Kyoichi Shimomura, Hisashi Satoh, Hideyo Noguchi, Seiichi Uchida, Ryuichi Kato   +6 more
openalex   +1 more source

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

Advanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier, Keerthi Thirtamara Rajamani, Shai Netser, Shlomo Wagner, Hala Harony‐Nicolas   +4 more
wiley   +1 more source

Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Proteins Interacting With the Third Cytoplasmic Loop of Dopamine D2 and D3 Receptors

Journal of Pharmacological Sciences, 2010
Among the various dopamine receptors, D2-like receptors (D2R, D3R, and D4R) are characterized by a large third cytoplasmic loop, a short carboxyl-terminal tail, and the ability to activate inhibitory G proteins.
Norifumi Shioda, Yusuke Takeuchi, Kohji Fukunaga   +2 more
doaj  

NO EVIDENCE FOR INVOLVEMENT OF DOPAMINERGIC RECEPTORS IN THE POSITIVE INOTROPIC ACTION OF DOPAMINE ON THE ISOLATED RABBIT PAPILLARY MUSCLE

, 1978
Shigeru Motomura, Otto‐Erich Brodde, Hans-Joachim Schümann   +2 more
openalex   +1 more source

Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system [PDF]

, 1989
Eric K. Richfield, John B. Penney, A. Byron Young   +2 more
openalex   +1 more source

Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

Advanced Science, EarlyView.
A vessel‐on‐a‐chip system is developed to replicate both physiological and pathological vessel cyclic stretches. Proteomic analysis reveals pressure‐overload‐induced vascular remodeling, including cellular response to mechanical cues, cellular oxidative stresses, ER stress, and ceramide biosynthesis activation in the vessel‐on‐a‐chip system, well ...
Yanjun Liu, Jianxujie Zheng, Lingyan Zhong, Zengyu Wang, Dan Zhao, Hong Lin, Xiaoxue Zhang, Ke Meng, Xiaoxia Yang, Dongxue Zhang, Ling Lin, Liang Qiao   +11 more
wiley   +1 more source

Dopamine internalization via Uptake2 and stimulation of intracellular D5-receptor-dependent calcium mobilization and CDP-diacylglycerol signaling

Frontiers in Pharmacology
Dopamine stimulates CDP-diacylglycerol biosynthesis through D1-like receptors, particularly the D5 subtype most of which is intracellularly localized.
Wenfei Kang, Arlette Deukam Siewe, Chizurum C. Oluigbo, Chizurum C. Oluigbo, Mercy O. Arijesudade, Eugen Brailoiu, Ashiwel S. Undieh, Ashiwel S. Undieh   +7 more
doaj   +1 more source

Dopamine receptor antagonism by the novel antianxiety drug, buspirone [PDF]

, 1983
BA McMillen, R.T. Matthews, MK Sanghera, PD Shepard, D.C. German   +4 more
openalex   +1 more source

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

Advanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan, Renwang Sheng, Weikun Li, Yinghua Tao, Zonghao Liu, Ning Yang, Syeda Safia Hashmi, Feiling Feng, Fangzhou Liu, Liqin Ge   +9 more
wiley   +1 more source

Nonspecific Effects of the Selective κ-Opioid Receptor AgonistU-50,488H on Dopamine Uptake and Release in PC12 Cells

Journal of Pharmacological Sciences, 2003
: κ-Opioid receptor agonists decrease the levels of extracellular dopamine in vivo and in vitro. However, the mechanism(s) underlying these actions are unclear.
Nuannoi Chudapongse, Seong-Youl Kim, Robert E. Kramer, Ing K. Ho   +3 more
doaj