Results 121 to 130 of about 2,665,909 (403)

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

open access: yesAdvanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost   +9 more
wiley   +1 more source

Activation of Dopamine D4 Receptors Is Protective Against Hypoxia/ Reoxygenation-Induced Cell Death in HT22 Cells

open access: yesJournal of Pharmacological Sciences, 2010
Several reports have shown that some dopamine receptor ligands modulate the ischemia–reperfusion injury in animal models; however, its underling mechanisms are still unclear. In this study, we sought to establish an in vitro experimental model of hypoxia/
Saori Shimada   +5 more
doaj  

Viscoelasticity, Lubricity, and Wear Prevention of Cross‐Linked Mucin Gels

open access: yesAdvanced Materials Interfaces, EarlyView.
Physiologically, biolubrication by mucus reduces friction and protects tissues from tribological stress, with mucins playing a key role. This study compares mucin‐based gels with distinct crosslinking architectures to explore their effect on the lubrication and wear prevention abilities of reconstituted mucin gels.
Chiara Gunnella   +2 more
wiley   +1 more source

Higher Binding of the Dopamine D3 Receptor-Preferring Ligand [11C]-(+)-Propyl-Hexahydro-Naphtho-Oxazin in Methamphetamine Polydrug Users: A Positron Emission Tomography Study

open access: yesJournal of Neuroscience, 2012
Positron emission tomography (PET) findings suggesting lower D2-type dopamine receptors and dopamine concentration in brains of stimulant users have prompted speculation that increasing dopamine signaling might help in drug treatment.
I. Boileau   +13 more
semanticscholar   +1 more source

Xerogel Films with Ordered Silica Nanorods Enable Fine‐Tuned Polarized Structural Colors in Modular Nanocomposite Films

open access: yesAdvanced Materials Technologies, EarlyView.
Xerogel films with aligned silica nanorods are prepared through a facile stretching and air‐drying approach. By controlling the alignment of silica nanorods and configuring multilayer film stacks, vibrant and tunable polarized structural colors with hues including green and orange are achieved.
Wu Wei   +4 more
wiley   +1 more source

Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens

open access: yesBMC Neuroscience, 2007
Background In both schizophrenia and addiction, pathological changes in dopamine release appear to induce alterations in the circuitry of the nucleus accumbens that affect coordinated thought and motivation. Dopamine acts principally on medium-spiny GABA
Schmauss Claudia   +2 more
doaj   +1 more source

Endogenous Dopamine and Endocannabinoid Signaling Mediate Cocaine-Induced Reversal of AMPAR Synaptic Potentiation in the Nucleus Accumbens Shell [PDF]

open access: yes, 2018
Repeated exposure to drugs of abuse alters the structure and function of neural circuits mediating reward, generating maladaptive plasticity in circuits critical for motivated behavior.
Hearing, Matthew   +3 more
core   +2 more sources

VASCULAR DOPAMINE RECEPTORS IN THE CANINE HINDLIMB [PDF]

open access: green, 1975
Christopher Bell   +3 more
openalex   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin   +8 more
wiley   +1 more source

Dopamine agonists in Parkinson’s disease: Impact of D1-like or D2-like dopamine receptor subtype selectivity and avenues for future treatment

open access: yesClinical Parkinsonism & Related Disorders, 2023
Dopamine agonists (DAs) have demonstrated efficacy for the treatment of Parkinson’s disease (PD) but are limited by adverse effects (AEs). DAs can vary considerably in their receptor subtype selectivity and affinity, chemical composition, receptor ...
Stuart H. Isaacson   +4 more
doaj  

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