Results 131 to 140 of about 312,634 (355)
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
Antagonistic actions of renal dopamine and 5‐hydroxytryptamine: endogenous 5‐hydroxytryptamine, 5‐HT1A receptors and antinatriuresis during high sodium intake [PDF]
, 1996 Patrício Soares‐da‐Silva +2 more
openalex +1 more source
Advanced Science, EarlyView.Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang +13 more
wiley +1 more source
Brain‐derived neurotrophic factor regulates the expression of D1 dopamine receptors [PDF]
, 2006 Thuy Do +2 more
openalex +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Auxiliary role of D5 dopamine receptor as a marker in paranoid schizophrenia patients
Psychiatry and Clinical Psychopharmacology, 2019 OBJECTIVE: Schizophrenia, commonly develops in adolescents and young adults and Paranoid is the most common type. Newly progress in molecular biology and imaging techniques has enabled new insight into schizophrenia research.
Mahkameh Soleiman Meygooni +4 more
doaj +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
D5 Dopamine Receptors are Required for Dopaminergic Activation of Phospholipase C [PDF]
, 2008 Asha Sahu +4 more
openalex +1 more source
Anxiety, aggression, reward sensitivity, and forebrain dopamine receptor expression in a laboratory rat model of early‐life disadvantage [PDF]
, 2023 Joseph S. Lonstein +8 more
openalex +1 more source
Advanced Science, EarlyView.Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang +12 more
wiley +1 more source