Results 321 to 330 of about 2,674,348 (398)

Gut-derived metabolite 3-methylxanthine enhances cisplatin-induced apoptosis via dopamine receptor D1 in a mouse model of ovarian cancer. [PDF]

mSystems
Mai Z, Han Y, Liang D, Mai F, Zheng H, Li P, Li Y, Ma C, Chen Y, Li W, Zhang S, Feng Y, Chen X, Wang Y.   +13 more
europepmc   +1 more source

Analysis of Dopamine Receptor D2 Gene Polymorphism and Correlation with Dyslipidemia in the Chinese Population. [PDF]

Mol Syndromol
Tan H, Wang Z, Zhang J, Huang M, Chen J, Li F, Tang L.   +6 more
europepmc   +1 more source

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Dopamine receptor pharmacology.

Trends in Pharmacological Sciences, 1994
Although antipsychotic drugs originally helped to discover dopamine receptors, the five dopamine receptors presently identified and cloned are facilitating the search for and discovery of more selective antipsychotic and antiparkinson drugs. The D1-like dopamine receptors, D1 and D5, are sensitive to the same drugs as the D1 receptor in native tissues,
P. Seeman, H. V. Tol
semanticscholar   +5 more sources

D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.

Science, 1990
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the substantia nigra. Severe movement disorders result from the loss of striatal dopamine in patients with Parkinson's disease ...
C. Gerfen, T. Engber, L. Mahan, Z. Susel, T. Chase, F. Monsma, D. Sibley   +6 more
semanticscholar   +1 more source

A Comparison of the Vascular Dopamine Receptor with Other Dopamine Receptors

Annual Review of Pharmacology and Toxicology, 1978
The dopamine (DA) receptor has had an interesting history. Unusual actions were attributed to the catecholamine for many years, but these effects were generally considered to be manifestations of activation of 0.and ,8-adrenergic receptors rather thap results of action of DA on a specific receptor (1). The pendulum now has swung the other way.
P H Volkman, J D Kohli, L I Goldberg
openaire   +3 more sources

Multiple receptors for dopamine

Nature, 1979
Pharmacological and biochemical criteria can be used to separate those dopamine receptors which are linked to the enzyme adenylyl cyclase and those which are not.
John W. Kebabian, Donald B. Calne
openaire   +3 more sources

Dopamine receptors

2012
Publisher Summary This chapter focuses on the role of dopamine receptors in neurotransmission, their structures, and their functions. Dopamine (DA) is one of the major monoamine neurotransmitters in the mammalian brain. It is generated by hydroxylation and decarboxylation of the amino acid tyrosine, and further metabolized into epinephrine and ...
Nikhil M. Urs, Sean M. Peterson, Marc G. Caron   +2 more
openaire   +2 more sources

Dopamine receptors: from structure to function.

Physiological Reviews, 1998
The diverse physiological actions of dopamine are mediated by at least five distinct G protein-coupled receptor subtypes. Two D1-like receptor subtypes (D1 and D5) couple to the G protein Gs and activate adenylyl cyclase.
C. Missale, S. Nash, S. Robinson, M. Jaber, M. Caron   +4 more
semanticscholar   +1 more source

Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects.

Archives of General Psychiatry, 1992
Positron emission tomography and selective radioligands were used to determine D1 and D2 dopamine receptor occupancy induced by neuroleptics in the basal ganglia of drug-treated schizophrenic patients.
L. Farde, A. Nordström, F. Wiesel, S. Pauli, C. Halldin, G. Sedvall   +5 more
semanticscholar   +1 more source