Background Dopamine receptors comprise two subgroups, Gs protein-coupled “D1-like” receptors (D1, D5) and Gi-coupled “D2-like” receptors (D2, D3, D4). In airways, both dopamine D1 and D2 receptors are expressed on airway smooth muscle and regulate airway
Nao Matsuyama+8 more
doaj +1 more source
Effect of risperidone on morphine-induced conditioned place preference and dopamine receptor D2 gene expression in male rat hippocampus. [PDF]
Arani ZM+4 more
europepmc +1 more source
Direct visualization and cellular localization of D1 and D2 dopamine receptors in rat forebrain by use of fluorescent ligands. [PDF]
Marjorie A. Ariano+5 more
openalex +1 more source
We report a poisoning with paliperidone palmitate, a once‐monthly, long‐acting injectable antipsychotic. The patient suffered from deep sedation and dystonia. She had been treated with extended release intramuscular paliperidone for several years and had received her last injection 8 days prior to admission.
Mariam Nersesjan+5 more
wiley +1 more source
Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5. [PDF]
Jeon HM+20 more
europepmc +1 more source
Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system [PDF]
Eric K. Richfield+2 more
openalex +1 more source
A dopamine receptor D2 genetic polymorphism associated with transition to mental disorders in a cohort of individuals with at-risk mental state for psychosis. [PDF]
Marques JH+10 more
europepmc +1 more source
Discrimination vs. Generation: The Machine Learning Dichotomy for Dopaminergic Hit Discovery [PDF]
Virtual screening plays a pivotal role in early drug discovery, traditionally dominated by physics-based methods. While these approaches offer detailed insights, they are often hindered by high computational costs, limited sampling, and forcefield inaccuracies.
arxiv
Biophysics of risk aversion based on neurotransmitter receptor theory [PDF]
Decision under risk and uncertainty has been attracting attention in neuroeconomics and neuroendocrinology of decision-making. This paper demonstrated that the neurotransmitter receptor theory-based value (utility) function can account for human and animal risk-taking behavior.
arxiv
Purification of brain D2 dopamine receptor. [PDF]
Ritchie Williamson+3 more
openalex +1 more source