Results 131 to 140 of about 48,073 (302)

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

No association of dopamine D2 receptor molecular variant Cys311 and schizophrenia in Chinese patients [PDF]

, 1996
Chia‐Hsiang Chen, Shih‐Hsiang Chien, Hai‐Gwo Hwu   +2 more
openalex   +1 more source

Critical insights into the potential risks of antipsychotic drugs to fish, including through effects on behaviour

Biological Reviews, EarlyView.
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett, A. Ross Brown, Samuel K. Maynard, Stewart F. Owen, Charles R. Tyler   +4 more
wiley   +1 more source

Developing Photoaffinity Probes for Dopamine Receptor D₂ to Determine Targets of Parkinson's Disease Drugs. [PDF]

ACS Chem Neurosci, 2022
Kim ST, Doukmak EJ, Flax RG, Gray DJ, Zirimu VN, de Jong E, Steinhardt RC.   +6 more
europepmc   +1 more source

Effect of pergolide treatment on insulin dysregulation in horses and ponies with pituitary pars intermedia dysfunction

Equine Veterinary Journal, EarlyView.
Abstract Background Due to the high frequency of laminitis reported for both conditions, the relationship between pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID), and the potential role of dopamine in modifying insulin secretion, requires further investigation.
Nicolas C. Galinelli, Nicholas J. Bamford, Madison L. Erdody, Skye A. Mackenzie, Tobias Warnken, Patricia A. Harris, Martin N. Sillence, Simon R. Bailey   +7 more
wiley   +1 more source

Photoaffinity labeling and purification of D2 dopamine receptor from bovine striata

, 1989
Hachiro Usui, Naomi Maeda, Yosuke Takahashi, Toshiaki Isobe, T. Okuyama   +4 more
openalex   +1 more source

Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents [PDF]

, 1995
SM Hersch, B.J. Ciliax, CA Gutekunst, HD Rees, C J Heilman, Ken Kin Lam Yung, J. Paul Bolam, E Ince, Hong Yi, Allan I. Levey   +9 more
openalex   +1 more source

The CRISPR‐Cas9 knockout DDC SH‐SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross‐sectional structural and functional analysis

The FEBS Journal, EarlyView.
Here, we generated a DDC‐KO cellular model for studying aromatic amino acid decarboxylase (AADC) deficiency. This model was created using CRISPR‐Cas9 in the SH‐SY5Y neuroblastoma cell line and was validated through the absence of the dopamine product and an altered l‐dopa metabolite profile.
Cristian Andres Carmona‐Carmona, Giovanni Bisello, Rossella Franchini, Gianluigi Lunardi, Roberta Galavotti, Massimiliano Perduca, Rui P. Ribeiro, Benny Danilo Belviso, Alejandro Giorgetti, Rocco Caliandro, Patricia M.‐J. Lievens, Mariarita Bertoldi   +11 more
wiley   +1 more source

Effects of Tall Fescue Endophyte Type and Dopamine Receptor D2 Genotype on Cow-Calf Performance during Late Gestation and Early Lactation. [PDF]

Toxins (Basel), 2021
Wilbanks SA, Justice SM, West T, Klotz JL, Andrae JG, Duckett SK.   +5 more
europepmc   +1 more source

Overexpression of the short isoform of the dopamine D2 receptor causes diet‐induced obesity and hyperglycemia in mice

Journal of Neuroendocrinology, EarlyView.
Alterations in the expression levels of D2S and D2L resulted in obesity and metabolic syndrome such as abdominal fat accumulation and hyperglycemia in D2L KO mice fed with a high‐fat diet, compared to WT mice. This may be partly due to increased food intake.
Hanna Gonzalez, Lei Cheng, Qing Chang, Paul E. Gold, Diego Perez‐Tilve, YanYan Wang   +5 more
wiley   +1 more source