Results 151 to 160 of about 121,521 (304)

Effect of pergolide treatment on insulin dysregulation in horses and ponies with pituitary pars intermedia dysfunction

Equine Veterinary Journal, EarlyView.
Abstract Background Due to the high frequency of laminitis reported for both conditions, the relationship between pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID), and the potential role of dopamine in modifying insulin secretion, requires further investigation.
Nicolas C. Galinelli, Nicholas J. Bamford, Madison L. Erdody, Skye A. Mackenzie, Tobias Warnken, Patricia A. Harris, Martin N. Sillence, Simon R. Bailey   +7 more
wiley   +1 more source

Not all partial dopamine D2 receptor agonists are the same in treating schizophrenia. Exploring the effects of bifeprunox and aripiprazole using a computer model of a primate striatal dopaminergic synapse

Neuropsychiatric Disease and Treatment, 2010
Athan Spiros1, Robert Carr1, Hugo Geerts1,21In Silico Biosciences, Berwyn, PA, USA; 2School of Medicine, University of Pennsylvania, PA, USAAbstract: Species differences in physiology and unique active human metabolites contribute to the limited ...
Athan Spiros, Robert Carr, Hugo Geerts
doaj  

Intestinal Dopamine Receptor D2 is Required for Neuroprotection Against 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Dopaminergic Neurodegeneration. [PDF]

Neurosci Bull, 2022
Peng H, Yu S, Zhang Y, Yin Y, Zhou J.
europepmc   +1 more source

Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. [PDF]

, 1991
Sergi Ferré, Gabriel von Euler, B. Johansson, Bertil B. Fredholm, Kjell Fuxé   +4 more
openalex   +1 more source

Dopamine genetic risk scores and psychiatric symptoms: Interacting risk factors for impulse control behaviours in de novo Parkinson's disease

Journal of Neuropsychology, EarlyView.
Abstract Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD.
Emma Whooley, Vincent Koppelmans, Hayley J. MacDonald, Alison Hall, Marit F. L. Ruitenberg   +4 more
wiley   +1 more source

The Role of Dopamine Receptor D2 in Bridging the Intention-Behavior Gap in Sport Participation. [PDF]

Int J Environ Res Public Health, 2021
Park S, Kwon J, Ahn C, Cho HS, Moon HY, Lee CG.   +5 more
europepmc   +1 more source

Site-directed mutagenesis of the human dopamine D2 receptor [PDF]

, 1992
Alfred Mansour, Fan Meng, James H. Meador‐Woodruff, Larry P. Taylor, Olivier Civelli, Huda Akil   +5 more
openalex   +1 more source

Relationship Between Cigarette Smoking and Awake Bruxism: Does Smoking Increase the Frequency of Masticatory Muscle Activities?

Journal of Oral Rehabilitation, EarlyView.
ABSTRACT Background Despite the aetiology of awake bruxism (AB) being prevalently linked to psychological factors, several studies suggested that the use of certain substances, such as tobacco smoking, can contribute to the increase in masticatory muscle activities (MMA) during wakefulness.
Ovidiu Ionut Saracutu, Matteo Pollis, Alessandro Bracci, Marco Ferrari, Daniele Manfredini   +4 more
wiley   +1 more source

Accelerating Discovery of Novel and Bioactive Ligands With Pharmacophore-Informed Generative Models [PDF]

arXiv
Deep generative models have gained significant advancements to accelerate drug discovery by generating bioactive chemicals against desired targets. Nevertheless, most generated compounds that have been validated for potent bioactivity often exhibit structural novelty levels that fall short of satisfaction, thereby providing limited inspiration to human
arxiv  

The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein.

, 1987
Susan E. Senogles, Jeffrey Benovic, N Amlaiky, Cecilia G. Unson, Graeme Milligan, R Vinitsky, Allen M. Spiegel, Marc G. Caron   +7 more
openalex   +1 more source