Results 211 to 220 of about 169,368 (383)

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

The American Journal on Addictions, Volume 34, Issue 6, Page 589-602, November 2025.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi, Priya Atodaria, Edmund Appiah‐Kubi, Zainab Shah, Elpidio Marlon Garcia   +4 more
wiley   +1 more source

Correction: Hu, W., et al. Targeting Dopamine Receptor D2 by Imipridone Suppresses Uterine Serous Cancer Malignant Phenotype. Cancers 2020, 12, 2436. [PDF]

Cancers (Basel), 2021
Hu W, Zhang L, Ferri-Borgogno S, Kwan SY, Lewis KE, Cun HT, Yeung TL, Soliman PT, Tarapore RS, Allen JE, Guan X, Lu KH, Mok SC, Au-Yeung CL.   +13 more
europepmc   +1 more source

Interaction of Arylpiperazines with the Dopamine Receptor D2 Binding Site

Arzneimittelforschung, 2005
V. Šukalović, M. Zlatović, D. Andrić, G. Roglic, S. Kostic-Rajacic, V. Soskic   +5 more
semanticscholar   +1 more source

The fast‐dissociating D2 antagonist antipsychotic JNJ‐37822681 is a neuronal Kv7 channel opener: Potential repurposing for epilepsy treatment

British Journal of Pharmacology, Volume 182, Issue 22, Page 5574-5595, November 2025.
Abstract Background and Purpose Pharmacological activation of neuronal M‐current mediated by Kv7 (Kv7.2–5) potassium channels is a validated mechanism for epilepsy treatment. However, since the market withdrawal of the prototype Kv7 activator retigabine, no Kv7 activator is clinically available for this condition.
Lidia Carotenuto, Oliver Keminer, Giusy Carleo, Andrea Zaliani, Antonio Leo, Rita Citraro, Giovambattista De Sarro, Nina Dirkx, Marcus Kaji, Sarah Weckhuysen, Jeanette Reinshagen, Vincenzo Barrese, Natascia Guida, Carmine Ostacolo, Francesco Miceli, Philip Gribbon, Maurizio Taglialatela   +16 more
wiley   +1 more source

Differential visualization of dopamine D2 and D3 receptors in rat brain

, 1993
Bruce Parsons, Michael Stanley, Jonathan A. Javitch   +2 more
openalex   +1 more source

Dopamine D2 receptor gene and alcoholism among four aboriginal groups and Han in Taiwan [PDF]

, 1997
Wei J. Chen, Mong‐Liang Lu, Yun‐Pung P. Hsu, Chiao‐Chicy Chen, Jeng‐Ming Yu, Andrew T. Cheng   +5 more
openalex   +1 more source

Structure‐based discovery of thiamine uptake inhibitors

British Journal of Pharmacology, Volume 182, Issue 22, Page 5611-5626, November 2025.
Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel, Björn Windshügel, Christian Löw   +2 more
wiley   +1 more source

Prediction of Therapeutic Doses of Antipsychotic Drugs as Dopamine D2 Receptor Antagonists. Approach Based on Receptor Occupancy Theory.

, 1993
Yasuhiko Yamada, Yasufumi Sawada, Risa Takayanagi, Kiyomi Ito, Kouichi Nakamura, Tatsuji Iga   +5 more
openalex   +2 more sources

Lack of Discrimination by Agonists for D2 and D3 Dopamine Receptors [PDF]

, 1995
Kevin D. Burris, Mary A. Pacheco, Theresa M. Filtz, Mei‐Ping Kung, Hank F. Kung, Perry B. Molinoff   +5 more
openalex   +1 more source

Brain Network Signature of Autoscopic Phenomena in Humans

CNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.
This study identified a common brain network underlying AP, encompassing bilateral angular gyrus, posterior medial cortex, intraparietal sulcus, cuneus, fusiform and insula, and uncovered its multimodal signatures. These findings advance our understanding of the network mechanisms of AP, as well as provide novel insights into bodily self‐consciousness.
Siyi Wang, Lei Qi, Xinqi Huang, Chunxue Wu, Jialin Du, Qing Xue, Jinghui Liu, Yuanhong Chen, Liankun Ren   +8 more
wiley   +1 more source