Results 221 to 230 of about 121,521 (304)

Advances in PET Imaging of α7 Nicotinic Receptors: From Radioligand Development to CNS Applications

Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 4, April 2025.
ABSTRACT Positron emission tomography (PET) has significantly advanced our understanding of the brain by enabling non‐invasive imaging and quantification of molecular processes, including receptor binding. In this review, we explore the development and application of PET radioligands targeting the α7 nicotinic acetylcholine receptor (α7 nAChR), a ...
Janus H. Magnussen
wiley   +1 more source

Dopamine receptor D2 genotype association with hyperprolactinemia

, 2004
K. Hansen, Y. Zhang, R. Colver, S. Tho, L. Plouffe, P. McDonough   +5 more
semanticscholar   +1 more source

Dual Role of Exosomes in Parkinson's Disease: Adenine Exerts a Beneficial Effect

CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.
Exosomes derived from the blood of healthy rats have therapeutic effects on pathology in PD mice; conversely, exosomes released by PD model rats cause PD‐like pathological features in healthy mice. Adenine, which is enriched in healthy exosomes, plays a key role in PD pathology by activating the cAMP/PKA signaling pathway.
Lei Chen, Yi‐Ting Shao, Ji Geng, Hua Liu, Qing‐Shan Liu, Yong Cheng, Ting Sun   +6 more
wiley   +1 more source

Analysis of Dopamine Receptor D2 Gene Polymorphism and Correlation with Dyslipidemia in the Chinese Population. [PDF]

Mol Syndromol
Tan H, Wang Z, Zhang J, Huang M, Chen J, Li F, Tang L.   +6 more
europepmc   +1 more source

Sex-Specific Role for Dopamine Receptor D2 in Dorsal Raphe Serotonergic Neuron Modulation of Defensive Acoustic Startle and Dominance Behavior. [PDF]

eNeuro, 2020
Lyon KA, Rood BD, Wu L, Senft RA, Goodrich LV, Dymecki SM.   +5 more
europepmc   +1 more source

Characterization of the Molecular Mechanisms Underlying Lurasidone‐Induced Acute Manic Episodes in Bipolar Depression: A Network Pharmacology and Molecular Docking Approach

CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.
This study is the first to systematically explore the molecular mechanisms underlying lurasidone‐induced acute manic episodes in people with bipolar depression using network pharmacology and molecular docking approaches. Our bioinformatics and computational analyses demonstrated that lurasidone may regulate the serotonergic synapse signaling pathway by
Chao Li, Lei Yang, Qiuyu Zhang, Ying Zhang, Ranli Li, Feng Jia, Lina Wang, Xiaoyan Ma, Hongjun Tian, Chuanjun Zhuo   +9 more
wiley   +1 more source

The regulation of D2 dopamine receptor gene expression: epigenetic factors should not be forgotten [PDF]

, 1999
Artūras Petronis
openalex   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

D1 AND D2 DOPAMINE RECEPTOR INVOLVEMENT IN THE DISCRIMINATIVE-STIMULUS EFFECTS OF CAFFEINE IN RATS

, 1996
E. R.M. Prinssen, Mark S. Kleven, Wouter Koek   +2 more
openalex   +1 more source

Dopamine D2 receptor gene and alcoholism among four aboriginal groups and Han in Taiwan [PDF]

, 1997
Wei J. Chen, Mong‐Liang Lu, Yun‐Pung P. Hsu, Chiao‐Chicy Chen, Jeng‐Ming Yu, Andrew T. Cheng   +5 more
openalex   +1 more source