Results 221 to 230 of about 99,139 (322)

A double‐blind study on ulotaront's impact on weight‐related parameters in schizophrenia patients with metabolic syndrome and prediabetes: Part II

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 94-102, January 2026.
Abstract Aims Antipsychotics increase metabolic syndrome (MetSyn) and diabetes risk. Preclinical and translational research data suggest that ulotaront, an investigational trace amine‐associated receptor 1 (TAAR1) agonist, may have beneficial metabolic effects.
Snezana Milanovic   +11 more
wiley   +1 more source

Targeting Dopamine Receptor D2 by Imipridone Suppresses Uterine Serous Cancer Malignant Phenotype. [PDF]

open access: yesCancers (Basel), 2020
Hu W   +13 more
europepmc   +1 more source

Striatal Nitric Oxide Activity Better Predicts Motor Disability Than Proto‐Oncogenes

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 1, January 2026.
The figure summarizes the experimental design in which mice received a single intraperitoneal injection of saline, haloperidol, metoclopramide, or L‐NOARG at different doses. Extrapyramidal (EPS) side effects were assessed using the catalepsy test and the Rota‐rod test.
Sonia Guerrero Prieto   +3 more
wiley   +1 more source

High striatal occupancy of D2-like dopamine receptors by amisulpride in the brain of patients with schizophrenia [PDF]

open access: bronze, 2004
Ingo Vernaleken   +8 more
openalex   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 1, January 2026.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi   +4 more
wiley   +1 more source

Essential Roles of Heparan Sulfate Endosulfatase Sulf1 in Reward and Aversion Learning Through Distinct Dopamine D1 and D2 Receptor Pathways in Male Mice

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
In the nucleus accumbens (NAc), a heparan sulfate endosulfatase Sulf1 is expressed in both dopamine D1 receptor (Drd1) expressing and Drd2‐expressing medium spiny neurons (D1‐MSNs and D2‐MSNs, respectively). Sulf1 knockout (KO) mice showed impairment in both the cocaine‐induced conditioned place preference (CPP) test and inhibitory avoidance (IA) test.
Ken Miya   +8 more
wiley   +1 more source

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