Ropinirole Functions Through a Dopamine Receptor D2-Independent Mechanism to Ameliorate Amyotrophic Lateral Sclerosis Phenotypes in TARDBP-Mutant iPSC-Derived Motor Neurons. [PDF]
Asano H +8 more
europepmc +1 more source
Functionally selective activation of the dopamine receptor D2 is mirrored by the protein expression profiles. [PDF]
Wenk D +7 more
europepmc +1 more source
PACAP Signalling Network in the Nucleus Accumbens Core Regulates Reinstatement Behaviour in Rat. [PDF]
This study demonstrates the presence of PACAP signalling in the nucleus accumbens, a key brain region for reward processing. In cocaine‐experienced rats, intra‐accumbal PACAP microinjection blocked cocaine‐induced reinstatement and prevented reinstatement driven by D1 but not D2 receptor activation, indicating circuit specificity. In the absence of FDA‐
Bose S +7 more
europepmc +2 more sources
No association of dopamine D2 receptor molecular variant Cys311 and schizophrenia in Chinese patients [PDF]
Chia‐Hsiang Chen +2 more
openalex +1 more source
Abstract Background Due to the high frequency of laminitis reported for both conditions, the relationship between pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID), and the potential role of dopamine in modifying insulin secretion, requires further investigation.
Nicolas C. Galinelli +7 more
wiley +1 more source
Effects of intravenous injection of dopamine D2 receptor agonists on striatal neurons of rats.
Hiroaki Matsubayashi +2 more
openalex +1 more source
Predicting Symptomatic Response to Prokinetic Treatment Using Gastric Alimetry
Gastric Alimetry biomarkers may help in the prediction of prokinetic response in patients with chronic gastroduodenal symptoms. Lower postprandial amplitudes, indicating a reduced meal response, appear to predict benefit. ABSTRACT Background Chronic neurogastroduodenal disorders are challenging to manage, with therapy often initiated on a trial and ...
Chris Varghese +16 more
wiley +1 more source
Disease-Associated Dopamine Receptor D2 Variants Exhibit Functional Consequences Depending on Different Heterotrimeric G-Protein Subunit Combinations. [PDF]
Niebrügge N +3 more
europepmc +1 more source

