Results 31 to 40 of about 99,139 (322)

Dual role of dopamine D2-like receptors in the mediation of conditioned and unconditioned fear [PDF]

, 2012
A reduction of dopamine release or D2 receptor blockade in the terminal fields of the mesolimbic system, particularly the amygdala, clearly reduces conditioned fear.
Brandão, Marcus Lira, de Oliveira, Amanda Ribeiro, Muthuraju, Sangu, Colombo, Ana Caroline, Saito, Viviane Mitsuko, Talbot, Teddy   +5 more
core   +4 more sources

Effects on turning of microinjections into basal ganglia of D1 and D2 dopamine receptors agonists and the cannabinoid CB1 antagonist SR141716A in a rat Parkinson's model

Neurobiology of Disease, 2004
Brain cannabinoid CB1 receptors are expressed in neural areas that contribute to movement such as basal ganglia, where they co-localize with dopamine D1 and D2 receptors.
Fadwa El Banoua, Isabel Caraballo, Juan A Flores, Beatriz Galan-Rodriguez, Emilio Fernandez-Espejo   +4 more
doaj   +1 more source

Striatal dopamine D2 receptor binding of risperidone in schizophrenic patients as assessed by 123I-iodobenzamide SPECT: a comparative study with olanzapine [PDF]

, 2002
The aim of this investigation was to compare the degree of striatal dopamine-(D2) receptor blockade by two atypical antipsychotic drugs, risperidone and olanzapine.
Arndt J, B. Rossmüller, Dresel S, Duncan G E, E. M. Meisenzahl, G. J. E. Schmitt, Gerlach J, H.-j. Möller, K. Hahn, K. Tatsch, Kapur S, Kerwin R W, Marder S R, Meltzer H Y, Remington G, Richelson E, S. Dresel, T. Frodl, U. W. Preuss   +18 more
core   +1 more source

Low Dopamine D2/D3 Receptor Availability is Associated with Steep Discounting of Delayed Rewards in Methamphetamine Dependence. [PDF]

, 2015
BackgroundIndividuals with substance use disorders typically exhibit a predilection toward instant gratification with apparent disregard for the future consequences of their actions.
Ballard, Michael E, Dean, Andy C, Hsu, Eustace, Ishibashi, Kenji, London, Edythe D, Mandelkern, Mark A, Monterosso, John R, Robertson, Chelsea L   +7 more
core   +3 more sources

Depression of Serotonin Synaptic Transmission by the Dopamine Precursor L-DOPA

Cell Reports, 2015
Imbalance between the dopamine and serotonin (5-HT) neurotransmitter systems has been implicated in the comorbidity of Parkinson’s disease (PD) and psychiatric disorders.
Stephanie C. Gantz, Erica S. Levitt, Nerea Llamosas, Kim A. Neve, John T. Williams   +4 more
doaj   +1 more source

Cocaine-induced adaptation of dopamine D2S, but not D2L autoreceptors

eLife, 2017
The dopamine D2 receptor has two splice variants, D2S (Short) and D2L (Long). In dopamine neurons, both variants can act as autoreceptors to regulate neuronal excitability and dopamine release, but the roles of each variant are incompletely characterized.
Brooks G Robinson, Alec F Condon, Daniela Radl, Emiliana Borrelli, John T Williams, Kim A Neve   +5 more
doaj   +1 more source

Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants [PDF]

, 2014
Within the nucleus accumbens (NAc), synaptic GABAA receptors (GABAARs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine.
Belelli, D, Dixon, C I, Herd, M B, King, S L, Lambert, J J, MacPherson, T, Maguire, E P, Stephens, D N, Swinny, J D   +8 more
core   +1 more source

Beta band modulation by dopamine D2 receptors in the primary motor cortex and pedunculopontine nucleus in a rat model of Parkinson’s disease

Brain Research Bulletin, 2022
Beta band (12–30 Hz) hypersynchrony within the basal ganglia-thalamocortical network has been suggested as a hallmark of Parkinson’s disease (PD) pathophysiology. Abnormal beta band oscillations are found in the pedunculopontine nucleus (PPN) and primary
Xuenan Wang, Min Li, Jinlu Xie, Dadian Chen, Xiwen Geng, Shuang Sun, Bo Liu, Min Wang   +7 more
doaj   +1 more source

Dopamine Activation Preserves Visual Motion Perception Despite Noise Interference of Human V5/MT [PDF]

, 2016
Copyright © 2016 Yousif et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any ...
Abou-El-Ela Bourquin, Bilal, Bhrugubanda, Vamsee, Fu, Richard, Schultz, Simon R, Seemungal, Barry M, Yousif, Nada   +5 more
core   +3 more sources

Antipsychotic Induced Dopamine Receptor Supersensitivity and It’s Clinical Implications

Jurnal Psikiatri Surabaya, 2022
Background : Schizophrenia is a serious mental disorder that requires multi-modal and continuous treatment, mainly with antipsychotic. Along with the increasing life expectancy of schizophrenic patients, various problems due to prolonged blocking of ...
Riko Lazuardi, Khairina Rina, Dianasari
doaj   +1 more source