Results 41 to 50 of about 44,270 (170)
PAIN Reports. Introduction:. The lateral parabrachial nucleus (LPBN), a crucial hub for integrating and modulating diverse sensory information, is known to express both D1 and D2 dopamine receptors and receive dopaminergic inputs.
Ho Koo +4 more
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Central interaction of ascorbic acid and D2 dopamine receptors on spatial learning and memory in adult male rats [PDF]
The Iranian Journal of Veterinary Science and Technology, 2014 Previous studies had reported that extracellular levels of ascorbic acid have modulatory effects on dopamine receptors. Both ascorbic acid and dopamine receptor have an important role in learning and memory processes.
Sima Nasri +4 more
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Molecular Brain, 2022 Recent research has suggested that the mesolimbic dopamine network that mainly terminates in the nucleus accumbens may positively control the peripheral immune system.
Daisuke Sato +12 more
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Cocaine Sensitization: Modulation by Dopamine D2 Receptors [PDF]
Cerebral Cortex, 2002 Repeated administration of cocaine progressively increases drug-induced locomotor activity. This study examined the role of dopamine D(1)- and D(2)-like receptors in the medial prefrontal cortex (mPFC) in mediating these sensitized behaviors. For initiation experiments, animals received bilateral intra-mPFC injections of either saline, the D(1)-like ...
Chad E, Beyer, Jeffery D, Steketee
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Modulatory Effects of Dopamine D2 Receptors on Spreading Depression in Rat Somatosensory Neocortex
Basic and Clinical Neuroscience, 2014 Introduction: Spreading depression (SD) is a propagating wave of depolarization followed by depression of the neuroglial activities and can modulate extracellular dopamine concentrations in the neocortex.
Anna Maria Haarmann +3 more
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Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia
Frontiers in Pharmacology, 2020 Dopamine receptors are widely distributed within the brain where they play critical modulator roles on motor functions, motivation and drive, as well as cognition.
Jean Claude Martel +1 more
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Heterodimeric D1-D2 dopamine receptors: a review [PDF]
Biomeditsinskaya Khimiya, 2017 This review summarizes modern data on the structure and functions ofheteromersformed by D1 and D2 dopamine receptors focusing on their role in the mechanisms of drug dependence. This article discusses potential functional significance of heterodimeric D1-D2 dopamine receptorsdue to their localization in the brain as well as unique pharmacological ...
N L, Vekshina +3 more
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Molecular Brain, 2021 Dopamine is a key neurotransmitter that regulates attention through dopamine D1 and D2-receptors in the prefrontal cortex (PFC). We previously developed an object-based attention test (OBAT) to evaluate attention in mice.
Bolati Wulaer +6 more
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Plasma Membrane Compartmentalization of D2 Dopamine Receptors [PDF]
Journal of Biological Chemistry, 2013 Plasma membrane microcompartments could allow different signaling pathways to operate more efficiently and prevent cross-talk. We utilized a novel in-cell biotin transfer assay to demonstrate that the majority of plasma membrane-expressed D2 dopamine receptor (D2R) is microcompartmentalized within detergent-resistant structures.
Sharma, Meenakshi +3 more
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Cell Reports, 2019 Summary: Variations in the human FTO gene have been linked to obesity and altered connectivity of the dopaminergic neurocircuitry. Here, we report that fat mass and obesity-associated protein (FTO) in dopamine D2 receptor-expressing medium spiny neurons (
Johan Ruud +17 more
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