Results 241 to 250 of about 112,428 (350)

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel   +3 more
wiley   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

Comparative Analysis of Metal Preloading Technologies in Batteries and Capacitors

open access: yesEcoEnergy, EarlyView.
Metal preloading strategies play an important role in efficient batteries and hybrid capacitors to compensate for the consumed metals at the first discharge. This article reviews recent progress in preloading technologies in lithium‐ion and other metal‐ion systems.
Xuexue Pan   +3 more
wiley   +1 more source

Engineered Metal–Organic Frameworks‐Based Materials for Environmental Detection

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Engineered metal–organic frameworks (MOFs) regulated by various material modification strategies are discussed for environmental contaminant detection under different sensing mechanisms, providing future improvements of MOFs in environmental detection. Sensitive and selective detection of contaminants is crucial for environmental protection.
Pan Gao   +3 more
wiley   +1 more source

Altered GABAergic Homeostasis in the Striatum of Dopamine Transporter Knockout Rats. [PDF]

open access: yesCurr Neuropharmacol
Targa G   +6 more
europepmc   +1 more source

Electronic Synergy in NiCo‐Embedded Nitrogen‐Doped Hollow Mesoporous Carbon Spheres for Bifunctional Oxygen Catalysis and Zinc–Air Batteries

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study employs a hard‐templating etching strategy to synthesize N‐doped hollow mesoporous carbon spheres embedded with NiCo nanoparticles (denoted as NiCo@N‐HMCS). The optimized catalyst exhibits exceptional bifunctional catalytic activity for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) in alkaline media, achieving a ...
Pengyu Tan   +6 more
wiley   +1 more source

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