Results 91 to 100 of about 16,506,777 (367)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Capacity of the Energy Harvesting Channel with a Finite Battery
, 2016 We consider an energy harvesting channel, in which the transmitter is powered by an exogenous stochastic energy harvesting process $E_t$, such that $0\leq E_t\leq\bar{E}$, which can be stored in a battery of finite size $\bar{B}$. We provide a simple and
Nguyen, Phan-Minh +2 more
core +1 more source
Escalas de dor no paciente crítico: uma revisão integrativa
, 2013 A dor deve ter grande importância para aenfermagem nos cenarios hospitalares, pois econsiderada o quinto sinal vital. Os pacientesmanifestam dor de diversas maneiras e existemescalas que a avaliam a fim de conduzir a terapeuticaadequada.
J. S. Fortunato +3 more
semanticscholar +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Brazilian Journal of Anesthesiology, 2016 Introduction: Most cancer patients are treated with chemotherapy, and peripheral neuropathy is a serious and common clinical problem affecting patients undergoing cancer treatment.
Anamada Barros Carvalho +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
, 2013 Estudos tem demonstrado que individuos que apresentam dor lombar na infância e adolescencia sao acometidos tambem na vida adulta, reforcando a importância de que as causas sejam investigadas desde a idade escolar.
A. Lemos +5 more
semanticscholar +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Postoperative persistent chronic pain: what do we know about prevention, risk factors, and treatment
Brazilian Journal of Anesthesiology, 2016 Background and objectives: Postoperative persistent chronic pain (POCP) is a serious health problem, disabling, undermining the quality of life of affected patients.
Durval Campos Kraychete +4 more
doaj +1 more source