Results 71 to 80 of about 916,549 (292)
Systematic Reviews, 2018 Background Low back pain (LBP) is one of the most prevalent and recurrent conditions in the general population, with personal, professional, social and economic impact.
Liliane Mendonça +2 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Improved Training for Self-Training by Confidence Assessments
, 2018 It is well known that for some tasks, labeled data sets may be hard to gather. Therefore, we wished to tackle here the problem of having insufficient training data.
Bank, Dor, Greenfeld, Daniel, Hyams, Gal
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Brazilian Journal of Anesthesiology, 2016 Introduction: Most cancer patients are treated with chemotherapy, and peripheral neuropathy is a serious and common clinical problem affecting patients undergoing cancer treatment.
Anamada Barros Carvalho +3 more
doaj +1 more source
Can Feedback Increase the Capacity of the Energy Harvesting Channel?
, 2015 We investigate if feedback can increase the capacity of an energy harvesting communication channel where a transmitter powered by an exogenous energy arrival process and equipped with a finite battery communicates to a receiver over a memoryless channel.
Ozgur, Ayfer +2 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Postoperative persistent chronic pain: what do we know about prevention, risk factors, and treatment
Brazilian Journal of Anesthesiology, 2016 Background and objectives: Postoperative persistent chronic pain (POCP) is a serious health problem, disabling, undermining the quality of life of affected patients.
Durval Campos Kraychete +4 more
doaj +1 more source
XMM-Newton study of 30 Dor C and a newly identified MCSNR J0536-6913 in the Large Magellanic Cloud
, 2014 Aims: We present a study of the superbubble (SB) 30 Dor C and the newly identified MCSNR J0536-6913 in the LMC. Methods: All available XMM-Newton data (exposure times of 420 ks EPIC-pn, 556 ks EPIC-MOS1, 614 ks EPIC-MOS2) were used to characterise the ...
Bozzetto, L. M. +6 more
core +1 more source