Results 61 to 70 of about 16,506,777 (367)

Desafios contemporâneos da saúde do trabalhador [PDF]

, 2021
Kátia Reis de Souza, Gideon Borges dos Santos, Luciana Gomes, Maria de Fátima Ramos Moreira, Renato José Bonfatti, Rosangela Laurentino Brito   +5 more
openalex   +1 more source

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

Nature Communications, 2018
Methylation patterns of circulating cell-free DNA (cfDNA) contain rich information about recent cell death events in the body. Here, we present an approach for unbiased determination of the tissue origins of cfDNA, using a reference methylation atlas of ...
J. Moss, J. Magenheim, D. Neiman, Hai Zemmour, Netanel Loyfer, A. Korach, Yaacov Samet, M. Maoz, H. Druid, P. Arner, Keng-Yeh Fu, E. Kiss, K. Spalding, G. Landesberg, A. Zick, A. Grinshpun, A. J. Shapiro, M. Grompe, Avigail Dreazan Wittenberg, B. Glaser, R. Shemer, Tommy Kaplan, Y. Dor   +22 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Tradução, adaptação cultural e validação da versão portuguesa do instrumento “knowledge and attitudes survey regarding pain” (kasrp)

Onco.News, 2019
As lacunas na formação dos profissionais de saúde têm sido apontadas como a principal causa de sofrimento inaceitável à luz do conhecimento atual. O Knowledge and Attitudes Survey Regarding Pain (KASRP) é um instrumento com 41 itens que mede as ...
Luís Manuel Batalha, Ana Cristina Ferreira, Ana Leonor Ribeiro, Carina Raposo, Daniela Dias, Juliana Santos, Isabel Maria Tarico Bico Correia, António Gomes de Oliveira, Teófilo Ângelo Dias de Sousa   +8 more
doaj   +1 more source

Endometriosis: A Disease with Few Direct Treatment Options

Molecules, 2022
Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility in addition to high treatment costs.
Patricia Ribeiro de Carvalho França, Anna Carolina Pereira Lontra, Patricia Dias Fernandes   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Brown Dwarfs in Young Moving Groups from Pan-STARRS1. I. AB Doradus

, 2015
Substellar members of young ($\lesssim$150 Myr) moving groups are valuable benchmarks to empirically define brown dwarf evolution with age and to study the low-mass end of the initial mass function.
Aller, Kimberly M., Best, William M. J., Burgett, William S., Chambers, Kenneth C., Flewelling, Heather, Hodapp, Klaus W., Kaiser, Nick, Kotson, Michael C., Liu, Michael C., Magnier, Eugene A., Metcalf, Nigel, Tonry, John L., Wainscoat, Richard J., Waters, Christopher   +13 more
core   +1 more source

Kinesio taping: aplicação e seus resultados sobre a dor: revisão sistemática

, 2014
O Kinesio taping vem sendo utilizado cada vez mais em diversas condicoes, porem, seu efeito hipoalgesico e mecanismo de acao nao apresentam resultado cientifico.
D. P. Artioli, G. Bertolini
semanticscholar   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Randomized prospective study of three different techniques for ultrasound-guided axillary brachial plexus block

Brazilian Journal of Anesthesiology, 2018
Introduction: Randomized prospective study comparing two perivascular techniques with the perineural technique for ultrasound-guided axillary brachial plexus block (US-ABPB).
Leonardo Henirque Cunha Ferraro, Alexandre Takeda, Paulo César Castello Branco de Sousa, Fernanda Moreira Gomes Mehlmann, Jorge Kiyoshi Mitsunaga Junior, Luiz Fernando dos Reis Falcão   +5 more
doaj   +1 more source