Results 71 to 80 of about 16,506,777 (367)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Online Power Control for Block i.i.d. Energy Harvesting Channels

open access: yes, 2017
We study the problem of online power control for energy harvesting communication nodes with random energy arrivals and a finite battery. We assume a block i.i.d.
Shaviv, Dor, Özgür, Ayfer
core   +1 more source

All finite transitive graphs admit self-adjoint free semigroupoid algebras

open access: yes, 2020
In this paper we show that every non-cycle finite transitive directed graph has a Cuntz-Krieger family whose WOT-closed algebra is $B(\mathcal{H})$. This is accomplished through a new construction that reduces this problem to in-degree $2$-regular graphs,
Dor-On, Adam, Linden, Christopher
core   +1 more source

Effects of the positive end-expiratory pressure increase on sublingual microcirculation in patients with acute respiratory distress syndrome

open access: yesBrazilian Journal of Anesthesiology, 2017
Objective: The aim of this study was to evaluate the impact of increased positive end-expiratory pressure on the sublingual microcirculation. Methods: Adult patients who were sedated, under mechanical ventilation, and had a diagnosis of circulatory shock
Nathaly Fonseca Nunes   +5 more
doaj   +1 more source

Approach to Headache in Patients with COVID-19

open access: yesActa Médica Portuguesa, 2021
N/a.
Andreia Costa   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Improved Training for Self-Training by Confidence Assessments

open access: yes, 2018
It is well known that for some tasks, labeled data sets may be hard to gather. Therefore, we wished to tackle here the problem of having insufficient training data.
Bank, Dor, Greenfeld, Daniel, Hyams, Gal
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Can Feedback Increase the Capacity of the Energy Harvesting Channel?

open access: yes, 2015
We investigate if feedback can increase the capacity of an energy harvesting communication channel where a transmitter powered by an exogenous energy arrival process and equipped with a finite battery communicates to a receiver over a memoryless channel.
Ozgur, Ayfer   +2 more
core   +1 more source

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