Results 21 to 30 of about 653,638 (208)

Effects of Lateral Habenula 2-Arachidonoylglycerol Manipulation on Dorsal Raphe Nucleus Immediate Early Gene Expression [PDF]

open access: yes, 2022
It is yet unknown how manipulation of endocannabinoid signaling in the lateral habenula alters coping strategies. Given the strong inhibitory influence of the lateral habenula over dorsal raphe serotonin neurons and the ability of stress to recruit ...
Urrutia-Camargo, Rafael
core   +1 more source

Coding of Task Reward Value in the Dorsal Raphe Nucleus [PDF]

open access: yesThe Journal of Neuroscience, 2010
The dorsal raphe nucleus and its serotonin-releasing neurons are thought to regulate motivation and reward-seeking. These neurons are known to be active during motivated behavior, but the underlying principles that govern their activity are unknown.
Ethan S, Bromberg-Martin   +2 more
openaire   +2 more sources

Localisation and stress-induced plasticity of GABAA receptor subunits within the cellular networks of the mouse dorsal raphe nucleus [PDF]

open access: yes, 2015
The dorsal raphe nucleus (DRN) provides the major source of serotonin to the central nervous system (CNS) and modulates diverse neural functions including mood.
Lambert, Jeremy J.   +5 more
core   +1 more source

Cellular effects of swim stress in the dorsal raphe nucleus [PDF]

open access: yesPsychoneuroendocrinology, 2007
Swim stress regulates forebrain 5-hydroxytryptamine (5-HT) release in a complex manner and its effects are initiated in the serotonergic dorsal raphe nucleus (DRN). The purpose of this study was to examine the effects of swim stress on the physiology of DRN neurons in conjunction with 5-HT immunohistochemistry. Basic membrane properties, 5-HT(1A) and 5-
Lynn G, Kirby   +6 more
openaire   +2 more sources

Extrasynaptic glycine receptors of rodent dorsal raphe serotonergic neurons:a sensitive target for ethanol [PDF]

open access: yes, 2014
Alcohol abuse is a significant medical and social problem. Several neurotransmitter systems are implicated in ethanol's actions, with certain receptors and ion channels emerging as putative targets.
Corteen, Nicole   +16 more
core   +1 more source

Activity in human dorsal raphe nucleus signals changes in behavioural policy. [PDF]

open access: yesNat Commun
The dorsal raphe nucleus (DRN) is an important source of serotonin to the human forebrain, however there is little consensus about its behavioural function.
Priestley L   +4 more
europepmc   +2 more sources

Single-prolonged stress induces apoptosis in dorsal raphe nucleus in the rat model of posttraumatic stress disorder

open access: yesBMC Psychiatry, 2012
Introduction Post-traumatic stress disorder (PTSD) is an anxiety disorder that develops after exposure to a life-threatening traumatic experience. Meta-analyses of the brainstem showed that midsagittal area of the pons was significantly reduced in ...
Liu Dongjuan   +4 more
doaj   +1 more source

Region- and receptor-specific effects of chronic social stress on the central serotonergic system in mice

open access: yesIBRO Neuroscience Reports, 2021
Serotonin (5-HT), via its receptors expressed in discrete brain regions, modulates aversion and reward processing and is implicated in various psychiatric disorders including depression.
Simone Carneiro-Nascimento   +7 more
doaj   +1 more source

Prefrontal afferents to the dorsal raphe nucleus in the rat

open access: yesBrain Research Bulletin, 2009
The prefrontal cortex (PFC) receives strong inputs from monoaminergic cell groups in the brainstem and also sends projections to these nuclei. Recent evidence suggests that the PFC exerts a powerful top-down control over the dorsal raphe nucleus (DR) and that it may be involved in the actions of pharmaceutical drugs and drugs of abuse.
Luciano, Gonçalves   +3 more
openaire   +2 more sources

Presynaptic gating of excitation in the dorsal raphe nucleus by GABA [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
Significance Using a combination of approaches, a unique organization of the synaptic architecture of the dorsal raphe nucleus is revealed. That is, presynaptic GABAergic and glutamatergic boutons often pair with each other and converge on a single postsynaptic target, forming synaptic triads.
Mariano, Soiza-Reilly   +3 more
openaire   +2 more sources

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