Results 41 to 50 of about 1,237,495 (192)
Molecular Pain, 2018 Background Diabetic neuropathic pain is poorly controlled by analgesics, and the precise molecular mechanisms underlying hyperalgesia remain unclear. The KCNQ2/3/5 channels expressed in dorsal root ganglion neurons are important in pain transmission. The
Ting Yu +5 more
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A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes [PDF]
, 2005 We investigated the role of small-conductance calcium-activated potassium (SK) and intermediate-conductance calcium-activated potassium channels in modulating sensory transmission from peripheral afferents into the rat spinal cord.
Jowett, AJ +7 more
core
Emergence of functional sensory subtypes as defined by transient receptor potential channel expression [PDF]
, 2007 The existence of heterogeneous populations of dorsal root ganglion (DRG) neurons conveying different somatosensory information is the basis for the perception of touch, temperature, and pain. A differential expression of transient receptor potential (TRP)
Hjerling-Leffler, J +4 more
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EVALUATION OF THE LUMBAR SAFETY TRIANGLE THROUGH MAGNETIC RESONANCE IMAGING
Coluna/Columna, 2019 Objective: To evaluate the lumbar triangular safety zone, its boundaries and its relationship with the dorsal root ganglion through Magnetic Resonance Imaging (MRI).
Fernando Augusto Dannebrock +8 more
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Therapeutic Advances in Chronic Disease, 2023 Sensitization of dorsal horn ganglion sensory neuron plays a crucial role in the maintenance of chronic pain disorder. Multiple interventions targeting dorsal horn ganglion can provide considerable relief of pain, including selective nerve root block ...
Qiao Wang +5 more
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Neurons Undergo Apoptosis in Animal and Cell Culture Models of Diabetes
Neurobiology of Disease, 1999 Recent clinical trials indicate that the severity of diabetic neuropathy is correlated with the level of patient glycemic control. In the current study, hyperglycemia induces apoptotic changes in dorsal root ganglion neurons and Schwann cells in vivo ...
James W. Russell +4 more
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Spine, 2011 The mechanisms of apoptosis behind the formation of tissue reactions at the surface of the dorsal root ganglion (DRG) exposed to the nucleus pulposus were studied with special reference to the role of interleukin-6 (IL-6), using electron microscopy and immunohistochemistry in rats.To study the role of IL-6 on the DRG.It has been reported that nucleus ...
Yasuaki, Murata +6 more
openaire +3 more sources
Immortalized Dorsal Root Ganglion Neuron Cell Lines
Frontiers in Cellular Neuroscience, 2020 Pain is one of the most significant causes of suffering and disability world-wide, and arguably the most burdensome global health challenge. The growing number of patients suffering from chronic pain conditions such as fibromyalgia, complex regional pain
Rainer Viktor Haberberger +2 more
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Acta Neuropathologica Communications, 2022 Evolving evidence has supported the existence of two anatomically distinct Lewy-related pathology (LRP) types. Investigation of spinal cord and peripheral LRP can elucidate mechanisms of Lewy body disorders and origins of synuclein accumulation.
Anna Raunio +12 more
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Molecular Pain, 2017 Background Pain in patients with chronic pancreatitis is critical hallmark that accompanied inflammation, fibrosis, and destruction of glandular pancreas.
Hong-Yan Zhu +5 more
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