Results 21 to 30 of about 1,237,495 (192)
New Treatments for Spinal Nerve Root Avulsion Injury
Frontiers in Neurology, 2016 Further progress in the treatment of the longitudinal spinal cord injury has been made. In an inverted translational study, it has been demonstrated that return of sensory function can be achieved by bypassing the avulsed dorsal root ganglion neurons ...
Thomas Carlstedt
doaj +1 more source
Molecular Pain, 2019 Previously we reported that a group of inflammatory mediators significantly enhanced resurgent currents in dorsal root ganglion neurons. To understand the underlying intracellular signaling mechanism, we investigated the effects of inhibition of ...
Bin Wu +6 more
doaj +1 more source
Molecular Pain, 2020 Low back pain is a chronic, highly prevalent, and hard-to-treat condition in the elderly. Clinical studies indicate that AXL, which belongs to the tyrosine kinase receptor subfamily, mediates pathological pain.
Lingli Liang +11 more
doaj +1 more source
Neural Regeneration Research[INLINE:1] Dorsal root ganglion neurons transmit peripheral somatic information to the central nervous system, and dorsal root ganglion neuron excitability affects pain perception.
Yanna Lian +3 more
doaj +1 more source
Neuronal cell lines as model dorsal root ganglion neurons
Molecular Pain, 2016 Background Dorsal root ganglion neuron-derived immortal cell lines including ND7/23 and F-11 cells have been used extensively as in vitro model systems of native peripheral sensory neurons.
Kathleen Yin BPharm +2 more
doaj +1 more source
Molecular Pain, 2020 Neuropathic pain can be generated by chronic compression of dorsal root ganglion (CCD). Stimulation of primary motor cortex can disrupt the nociceptive sensory signal at dorsal root ganglion level and reduce pain behaviors. But the mechanism behind it is
Jaisan Islam +4 more
doaj +1 more source
Molecular Pain, 2018 Our previous study reported the translocator protein to play a critical role in neuropathic pain and the possible mechanisms in the spinal cord. However, its mechanism in the peripheral nervous system is poorly understood.
Bingjie Ma +5 more
doaj +1 more source
Neurobiology of Disease, 2004 We have previously demonstrated that high concentrations of nerve growth factor suppress neurite outgrowth from sensory neurons. Inhibition could be mediated by either the p75NTR or TrkA receptor.
Anna M. Conti +3 more
doaj +1 more source
Dorsal Root Ganglion (DRG) and Chronic Pain
Anesthesiology and Pain Medicine, 2021 Context: Chronic neuropathic pain is a common condition, and up to 11.9% of the population have been reported to suffer from uncontrolled neuropathic pain. Chronic pain leads to significant morbidity, lowered quality of life, and loss of workdays, and thus carries a significant price tag in healthcare costs and lost productivity.
Amnon A. Berger +12 more
openaire +3 more sources
Molecular Pain, 2019 Electroacupuncture has been shown to effectively reduce chronic pain in patients with nerve injury. The underlying mechanisms are not well understood. Accumulated evidence suggests that purinergic P2X3 receptors (P2X3Rs) in dorsal root ganglion neurons ...
Yi Liang +5 more
doaj +1 more source