Results 61 to 70 of about 110,913 (229)

Anterograde Tracing From the Göttingen Minipig Motor and Prefrontal Cortex Displays a Topographic Subthalamic and Striatal Axonal Termination Pattern Comparable to Previous Findings in Primates

open access: yesFrontiers in Neural Circuits, 2021
Background: Deep brain stimulation (DBS) of the dorsal subthalamic nucleus (STN) is a validated neurosurgical treatment of Parkinson’s Disease (PD).
Johannes Bech Steinmüller   +9 more
doaj   +1 more source

Neuroimaging in Functional Movement Disorders. [PDF]

open access: yes, 2019
PURPOSE OF REVIEW: Functional movement disorders are common and disabling causes of abnormal movement control. Here, we review the current state of the evidence on the use of neuroimaging in Functional movement disorders, particularly its role in helping
Edwards, MJ, Roelofs, JJ, Teodoro, T
core   +2 more sources

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

Cerebral Inefficient Activation in Schizophrenia Patients and Their Unaffected Parents during the N-Back Working Memory Task: A Family fMRI Study.

open access: yesPLoS ONE, 2015
BackgroundIt has been suggested that working memory deficits is a core feature of symptomatology of schizophrenia, which can be detected in patients and their unaffected relatives.
Sisi Jiang   +7 more
doaj   +1 more source

Trait anxiety and the neural efficiency of manipulation in working memory [PDF]

open access: yes, 2012
The present study investigates the effects of trait anxiety on the neural efficiency of working memory component functions (manipulation vs. maintenance) in the absence of threat-related stimuli.
Basten, Ulrike   +2 more
core   +1 more source

New craniodental materials of Falcarius utahensis (Theropoda: Therizinosauria) reveal patterns of intraspecific variation and cranial evolution in early coelurosaurians

open access: yesThe Anatomical Record, EarlyView.
Abstract Despite documented ecomorphological shifts toward an herbivorous diet in several coelurosaurian lineages, the evolutionary tempo and mode of these changes remain poorly understood, hampered by sparse cranial materials for early representatives of major clades. This is particularly true for Therizinosauria, with representative crania best known
William J. Freimuth, Lindsay E. Zanno
wiley   +1 more source

Divergent prefrontal activation between genders in depression during verbal fluency task: evidence from a large-scale fNIRS study

open access: yesAnnals of General Psychiatry
Background Depression exhibits marked sex differences in prevalence and clinical presentation, yet its neural underpinnings remain poorly understood.
Yan Zhang   +6 more
doaj   +1 more source

A functional magnetic resonance imaging study of pathophysiological changes responsible for mirror movements in Parkinson's disease. [PDF]

open access: yesPLoS ONE, 2013
Mirror movements correspond to involuntary movements observed in the limb contralateral to the one performing voluntary movement. They can be observed in Parkinson's disease (PD) but their pathophysiology remains unclear.
Alice Poisson   +9 more
doaj   +1 more source

Structural and functional abnormities of amygdala and prefrontal cortex in major depressive disorder with suicide attempts [PDF]

open access: yes, 2019
Finding neural features of suicide attempts (SA) in major depressive disorder (MDD) may be helpful in preventing suicidal behavior. The ventral and medial prefrontal cortex (PFC), as well as the amygdala form a circuit implicated in emotion regulation ...
Edmiston, Elliot K   +11 more
core   +1 more source

Towards a Developmental Retribution and Reciprocity Model (RRM): Implications for Youth Justice

open access: yesBehavioral Sciences &the Law, EarlyView.
ABSTRACT Youth justice systems are frequently justified by reference to developmental change, yet chronological age is often treated as a proxy for underlying psychological processes. This paper develops a Developmental Retribution and Reciprocity Model (RRM), integrating evolutionary criminology with contemporary developmental neuroscience to clarify ...
Evelyn Svingen
wiley   +1 more source

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