Encoding of Rules by Neurons in the Human Dorsolateral Prefrontal Cortex [PDF]
We use rules to extend learned behavior beyond specific instances to general scenarios. The prefrontal cortex (PFC) is thought to play an important role in representing rules, as evidenced by subjects who have difficulty in following rules after PFC damage and by animal studies demonstrating rule sensitivity of individual PFC neurons.
Matthew K, Mian +5 more
openaire +2 more sources
Methamphetamine-Triggered Neurotoxicity in Human Dorsolateral Prefrontal Cortex
Background: Methamphetamine (MA), is an extremely addictive stimulant that adversely affects the central nervous system. Accumulating evidence indicates that molecular mechanisms such as oxidative stress, apoptosis, and autophagy are involved in the toxicity of MA.
Zare, Ali +8 more
openaire +2 more sources
Specialization of the rostral prefrontal cortex for distinct analogy processes
Analogical reasoning is central to learning and abstract thinking. It involves using a more familiar situation (source) to make inferences about a less familiar situation (target).
Burgess, P. W. +10 more
core +1 more source
Stimulation of the right dorsolateral prefrontal cortex reduces conflict-induced forgetting. [PDF]
TMS to the dorsolateral prefrontal cortex demonstrates that right DLPFC is important for memory ...
Kovacs O +4 more
europepmc +2 more sources
Functional specialization within rostral prefrontal cortex (Area 10): a meta-analysis
One of the least well understood regions of the human brain is rostral prefrontal cortex, approximating Brodmann's area 10. Here, we investigate the possibility that there are functional subdivisions within this region by conducting a meta-analysis of ...
Christopher D. Frith +29 more
core +1 more source
Age differences in prefrontal surface area and thickness in middle aged to older adults
Age is associated with reductions in surface area and cortical thickness, particularly in prefrontal regions. There is also evidence of greater thickness in some regions at older ages.
Vonetta M Dotson +9 more
doaj +1 more source
Though we have a general understanding of the brain areas involved in motor sequence learning, there is more to discover about the neural mechanisms underlying skill acquisition.
Hannah K Ballard +3 more
doaj +1 more source
A pilot study to explore the effect of udenafil on cerebral hemodynamics in older adults
Objective Phosphodiesterase‐5 inhibitors (PDE5Is) enhance vasodilation. We investigated the effects of PDE5I on cerebral hemodynamics during cognitive tasks using functional near‐infrared spectroscopy (fNIRS).
Qi Wang +5 more
doaj +1 more source
Interval timing errors in a patient with thalamic chronotaraxis
Thalamic chronotaraxis is an isolated disorientation of time caused by the damage of thalamus, especially the mediodorsal nucleus. We performed interval timing trials on a patient with this phenomenon. Based on the results of those trials and compared to
R. Hayashi +3 more
doaj +1 more source
Effects of acupuncture stimulation on brain activation induced by cue-elicited alcohol craving
Acupuncture has been shown to be effective on alcohol use disorder. However, the underlying mechanism remains poorly understood. To investigate the effects of Shenmen (HT7) acupoint on brain activation induced by cue-elicited alcohol craving, 30 right ...
Hyeok Gyu Kwon +4 more
doaj +1 more source

