Ciglitazone—a human PPARγ agonist—disrupts dorsoventral patterning in zebrafish [PDF]
PeerJ, 2019 Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation.
Vanessa Cheng +3 more
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Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents [PDF]
Cell Reports, 2023 Summary: The general understanding of hippocampal circuits is that the hippocampus and the entorhinal cortex (EC) are topographically connected through parallel identical circuits along the dorsoventral axis.
Shinya Ohara +5 more
doaj +2 more sources
Opposite serotonergic modulation of sharp waves in the dorsal and ventral hippocampus [PDF]
Frontiers in Synaptic NeuroscienceSerotonin plays a crucial role in regulating hippocampal network dynamics, however, its effects on sharp wave–ripples (SPWs), a pattern fundamental for memory consolidation and emotional processing, remain incompletely understood, particularly along the ...
Charalampos L. Kandilakis +1 more
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Dynamic Mobilization Exercises Improve Activity and Stride Parameters Measured with Accelerometry in Sedentary Horses [PDF]
AnimalsDynamic mobilization exercises (DME) are an effective strategy to prevent musculoskeletal injuries and promote back health in sport horses. Previous studies focused mainly on multifidus muscle cross-sectional area, with limited data on locomotion and ...
Aritz Saitua +3 more
doaj +2 more sources
Shake a tail feather: the evolution of the theropod tail into a stiff aerodynamic surface. [PDF]
PLoS ONE, 2013 Theropod dinosaurs show striking morphological and functional tail variation; e.g., a long, robust, basal theropod tail used for counterbalance, or a short, modern avian tail used as an aerodynamic surface.
Michael Pittman +4 more
doaj +6 more sources
Cannabinoid Modulation of Excitability and Short-Term Neuronal Dynamics in the Dorsal and Ventral Hippocampus [PDF]
BiologyEndocannabinoids, acting primarily through CB1 receptors, are critical modulators of neuronal activity, influencing cognitive functions and emotional processing.
Giota Tsotsokou +5 more
doaj +2 more sources
Spreading depolarization is followed by seizure-like activation of the hippocampus: potential mechanism of migraine-aura triggered seizures [PDF]
The Journal of Headache and PainBackground Propagation of spreading depolarization (SD), a wave of transient cellular depolarization, over the cerebral cortex drives migraine aura symptoms.
Maria P. Smirnova +2 more
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Tris(1,3-dichloro-2-propyl) phosphate disrupts dorsoventral patterning in zebrafish embryos [PDF]
PeerJ, 2017 Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a high-production volume organophosphate flame retardant widely used within the United States. Within zebrafish, initiation of TDCIPP exposure at 0.75 h post-fertilization (hpf) results in genome-wide ...
Subham Dasgupta +5 more
doaj +7 more sources
Frontiers in Cellular Neuroscience, 2023 Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by intellectual disability and is related to autism. FXS is caused by mutations of the fragile X messenger ribonucleoprotein 1 gene (Fmr1) and is associated with alterations ...
Leonidas J. Leontiadis +5 more
doaj +1 more source
eLife, 2022 Local field potential (LFP) deflections and oscillations define hippocampal sharp-wave ripples (SWRs), one of the most synchronous events of the brain.
Andrea Navas-Olive +4 more
doaj +1 more source