Ciglitazone—a human PPARγ agonist—disrupts dorsoventral patterning in zebrafish [PDF]
PeerJ, 2019 Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation.
Vanessa Cheng +3 more
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Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents [PDF]
Cell Reports, 2023 Summary: The general understanding of hippocampal circuits is that the hippocampus and the entorhinal cortex (EC) are topographically connected through parallel identical circuits along the dorsoventral axis.
Shinya Ohara +5 more
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Modifying Factors of Adult Hippocampal Neurogenesis: A Dorsoventral Perspective in Health and Disease [PDF]
CellsAdult hippocampal neurogenesis (AHN) is a dynamic process that sustains neural plasticity and contributes to cognition, emotion, and stress resilience. While its functional significance in humans remains debated, growing evidence suggests that AHN plays ...
Ioannis Erginousakis +1 more
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The cellular logic of limb regeneration [PDF]
eLifeHierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.
Matthew Cherubino, Catherine D McCusker
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Opposite serotonergic modulation of sharp waves in the dorsal and ventral hippocampus [PDF]
Frontiers in Synaptic NeuroscienceSerotonin plays a crucial role in regulating hippocampal network dynamics, however, its effects on sharp wave–ripples (SPWs), a pattern fundamental for memory consolidation and emotional processing, remain incompletely understood, particularly along the ...
Charalampos L. Kandilakis +1 more
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Shake a tail feather: the evolution of the theropod tail into a stiff aerodynamic surface. [PDF]
PLoS ONE, 2013 Theropod dinosaurs show striking morphological and functional tail variation; e.g., a long, robust, basal theropod tail used for counterbalance, or a short, modern avian tail used as an aerodynamic surface.
Michael Pittman +4 more
doaj +6 more sources
Dynamic Mobilization Exercises Improve Activity and Stride Parameters Measured with Accelerometry in Sedentary Horses [PDF]
AnimalsDynamic mobilization exercises (DME) are an effective strategy to prevent musculoskeletal injuries and promote back health in sport horses. Previous studies focused mainly on multifidus muscle cross-sectional area, with limited data on locomotion and ...
Aritz Saitua +3 more
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Spreading depolarization is followed by seizure-like activation of the hippocampus: potential mechanism of migraine-aura triggered seizures [PDF]
The Journal of Headache and PainBackground Propagation of spreading depolarization (SD), a wave of transient cellular depolarization, over the cerebral cortex drives migraine aura symptoms.
Maria P. Smirnova +2 more
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eLife, 2022 Local field potential (LFP) deflections and oscillations define hippocampal sharp-wave ripples (SWRs), one of the most synchronous events of the brain.
Andrea Navas-Olive +4 more
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Frontiers in Cellular Neuroscience, 2023 Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by intellectual disability and is related to autism. FXS is caused by mutations of the fragile X messenger ribonucleoprotein 1 gene (Fmr1) and is associated with alterations ...
Leonidas J. Leontiadis +5 more
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