Results 11 to 20 of about 23,101 (254)

Spreading depolarization is followed by seizure-like activation of the hippocampus: potential mechanism of migraine-aura triggered seizures [PDF]

open access: yesThe Journal of Headache and Pain
Background Propagation of spreading depolarization (SD), a wave of transient cellular depolarization, over the cerebral cortex drives migraine aura symptoms.
Maria P. Smirnova   +2 more
doaj   +2 more sources

Rescue of sharp wave-ripples and prevention of network hyperexcitability in the ventral but not the dorsal hippocampus of a rat model of fragile X syndrome

open access: yesFrontiers in Cellular Neuroscience, 2023
Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by intellectual disability and is related to autism. FXS is caused by mutations of the fragile X messenger ribonucleoprotein 1 gene (Fmr1) and is associated with alterations ...
Leonidas J. Leontiadis   +5 more
doaj   +1 more source

Deep learning-based feature extraction for prediction and interpretation of sharp-wave ripples in the rodent hippocampus

open access: yeseLife, 2022
Local field potential (LFP) deflections and oscillations define hippocampal sharp-wave ripples (SWRs), one of the most synchronous events of the brain.
Andrea Navas-Olive   +4 more
doaj   +1 more source

Dorsoventral patterning in plants [PDF]

open access: yesGenes & Development, 1999
Although mutations affecting dorsoventral patterning in plants have been known for centuries (Linnaeus 1749), the underlying mechanisms controlling this process have remained mysterious. Recent papers by Sawa et al. (1999b) and others have begun to shed light on this subject through the isolation and characterization of genes responsible for ...
A, Sessions, M F, Yanofsky
openaire   +2 more sources

Increased Inhibition May Contribute to Maintaining Normal Network Function in the Ventral Hippocampus of a Fmr1-Targeted Transgenic Rat Model of Fragile X Syndrome

open access: yesBrain Sciences, 2023
A common neurobiological mechanism in several neurodevelopmental disorders, including fragile X syndrome (FXS), is alterations in the balance between excitation and inhibition in the brain. It is thought that in the hippocampus, as in other brain regions,
Leonidas J. Leontiadis   +5 more
doaj   +1 more source

Understanding Dorsoventral Topography [PDF]

open access: yesNeuron, 2002
Retinal axons project to their central targets along two orthogonal topographic axes, anterior-posterior (A-P) and dorsal-ventral (D-V). While ephrin-A/EphA signaling determines A-P topography, little has been known about the molecular mechanisms guiding axons along the D-V axis. Two papers by Mann et al. and Hindges et al.
Pittman, Andrew J, Chien, Chi-Bin
openaire   +2 more sources

Induction and Dorsoventral Patterning of the Telencephalon [PDF]

open access: yesNeuron, 2000
We thank Marina Mione, Lila Solnica-Krezel, Oscar Marin, Will Talbot, and Corinne Houart for advice and comments on the manuscript; Oscar Marin for help with figures; Susan Yu for help preparing the manuscript; and Tom Jessell and Eric Kandell for their remarkable patience. This work was supported by funds to J. L. R. R.
Wilson, Stephen W.   +1 more
openaire   +2 more sources

The asymmetric photosynthetic characteristics of the isobilateral sorghum leaves under the illumination of the diffuse light

open access: yesFrontiers in Plant Science, 2023
The difference between photosynthesis on the two leaf sides (dorsoventral asymmetry) of photosynthesis is important for light-use patterns, but the asymmetry is environment dependent.
Xiaolin Wang   +6 more
doaj   +1 more source

Generation of dorsoventral human spinal cord organoids via functionalizing composite scaffold for drug testing

open access: yesiScience, 2023
Summary: The spinal cord possesses highly complex, finely organized cytoarchitecture guided by two dorsoventral morphogenic organizing centers. Thus, generation of human spinal cord tissue in vitro is challenging. Here, we demonstrated a novel method for
Weiwei Xue   +7 more
doaj   +1 more source

Leaf structure of species of the Brassicaceae Burnett family in Southwestern Kyzylkum, Uzbekistan [PDF]

open access: yesCaspian Journal of Environmental Sciences
Leaf species of the family Brassicaceae have been studied, diagnostic features have been identified. Omitted by various types of trichomes: stellate, dendroid stomata are randomly arranged, numerous, non-submerged, mostly anomatid hemiparacytic ...
Gulbahar Tursinbayeva   +10 more
doaj   +1 more source

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