Results 91 to 100 of about 9,342 (307)

Treatment With Remdesivir Alone or in Combination With GS‐441524 in Cats With Ocular Involvement of Feline Infectious Peritonitis: An Observational Case Series

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
ABSTRACT Background Remdesivir and GS‐441524 have successfully treated cats with feline infectious peritonitis (FIP) but the changes in associated signs of ocular disease are not reported. Objective Evaluate the response of FIP‐associated signs of ocular disease before and after treatment with remdesivir, GS‐441524, or both.
Amy L. M. M. Andrews, Eneko Izaguirre, Jodie Green, Emma Scurrell, Savina Gogova, Sarah Tayler, Christiane Kafarnik   +6 more
wiley   +1 more source

Add-on Effect of Prostaglandin Analogues in Dorzolamide/Timolol Fixed Combination Treated Primary Open Angle Glaucoma Patients [PDF]

, 2022
Jae Hoon Lee, Sang Wook Jin
openalex   +1 more source

Beta2 adrenergic receptor silencing change intraocular pressure in New Zealand rabbits [PDF]

, 2017
Purpose/aim: Glaucoma consists of a group of progressive optic neuropathies that are characterized by degeneration of the optic nerve and irreversible visual filed loss.
Guzmán Aránguez, Ana Isabel, Loma Lozano, Patricia, Pintor, Jesús, Pérez de Lara, María Jesús   +3 more
core   +2 more sources

Effects of intracameral tissue plasminogen activator injection on posterior capsular opacification, fibrin formation, and intraocular pressure in dogs after phacoemulsification

Veterinary Ophthalmology, Volume 28, Issue 6, Page 917-925, November 2025.
Abstract Objective To evaluate whether intracameral tissue plasminogen activator (tPA) injection is effective in regulating posterior capsular opacification (PCO), fibrin formation and intraocular pressure (IOP) after cataract surgery. Animal Studied Prospective study involving 30 eyes of 21 dogs that underwent phacoemulsification.
Kyulee Kim, Young‐Sun Kang, Joon Young Kim   +2 more
wiley   +1 more source

Combination of Intravitreal Bevacizumab and Topical Dorzolamide versus Intravitreal Bevacizumab Alone for Diabetic Macular Edema: A Randomized Contralateral Clinical Trial

BioMed Research International, 2020
Purpose To evaluate the efficacy of three intravitreal bevacizumab (IVB) injections versus the same combined with 2% of topical dorzolamide in the treatment of diabetic macular edema (DME). Methods In this randomized double-masked clinical trial, 32 eyes
F. Fazel, Hossein Nikpour, M. Pourazizi
semanticscholar   +1 more source

Efficacy, safety and tolerability of combination therapy with timolol and dorzolamide in glaucoma and ocular hypertension

Drug, Healthcare and Patient Safety, 2010
Parul Ichhpujani1,2, L Jay Katz11William and Anna Goldberg Glaucoma Service, 1Wills Eye Institute, Philadelphia, PA, USA; 2Department of Ophthalmology, Government Medical College and Hospital, Chandigrah, IndiaAbstract: Combination pharmacotherapy has ...
Parul Ichhpujani, L Jay Katz
doaj  

Retrospective, controlled observational case study of patients with central retinal vein occlusion and initially low visual acuity treated with an intravitreal dexamethasone implant [PDF]

, 2016
Background Patients with initially low visual acuity were excluded from the therapy approval studies for retinal vein occlusion. But up to 28 % of patients presenting with central retinal vein occlusion have a baseline BCVA of less than 34 ETDRS letters (
Annabelle Eckert, Anne Rübsam, Antonia Maria Joussen, Daniel Pilger, Enken Gundlach, Gerrit Alexander vom Brocke, Juliane Schlomberg, Matthias Karl Klamann, Sibylle Winterhalter, Tina Dietrich-Ntoukas   +9 more
core   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, Volume 599, Issue 18, Page 2557-2570, September 2025.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

A novel stability indicating RP-HPLC method of related substances for dorzolamide hydrochloride and timolol maleate in glaucoma treatment ophthalmic formulation

Discover Chemistry
A sensitive and simultaneous RP-HPLC strategy has been developed for analysing timolol maleate and dorzolamide hydrochloride along with their related substances.
Harmeet Kaur Kohli, Satish K. Ghumare, Vijay A. Bagul   +2 more
doaj   +1 more source

Comparison of Intraocular Pressure, Blood Pressure, Ocular Perfusion Pressure and Blood Flow Fluctuations During Dorzolamide Versus Timolol Add-On Therapy in Prostaglandin Analogue Treated Glaucoma Subjects

Pharmaceuticals, 2012
Objective: To compare the effects of dorzolamide and timolol add-on therapy in open-angle glaucoma (OAG) patients previously treated with prostaglandin analogue (Pg), by evaluating fluctuations in the intraocular (IOP), blood (BP), ocular perfusion ...
Ruta Barsauskaite, Brent Siesky, Daiva Paulaviciute-Baikstiene, Vaida Diliene, Lina Siaudvytyte, Ingrida Januleviciene, Alon Harris   +6 more
doaj   +1 more source