Results 71 to 80 of about 6,478 (222)

Efficacy, safety and tolerability of combination therapy with timolol and dorzolamide in glaucoma and ocular hypertension

Drug, Healthcare and Patient Safety, 2010
Parul Ichhpujani1,2, L Jay Katz11William and Anna Goldberg Glaucoma Service, 1Wills Eye Institute, Philadelphia, PA, USA; 2Department of Ophthalmology, Government Medical College and Hospital, Chandigrah, IndiaAbstract: Combination pharmacotherapy has ...
Parul Ichhpujani, L Jay Katz
doaj  

Comparison of Intraocular Pressure, Blood Pressure, Ocular Perfusion Pressure and Blood Flow Fluctuations During Dorzolamide Versus Timolol Add-On Therapy in Prostaglandin Analogue Treated Glaucoma Subjects

Pharmaceuticals, 2012
Objective: To compare the effects of dorzolamide and timolol add-on therapy in open-angle glaucoma (OAG) patients previously treated with prostaglandin analogue (Pg), by evaluating fluctuations in the intraocular (IOP), blood (BP), ocular perfusion ...
Ruta Barsauskaite, Brent Siesky, Daiva Paulaviciute-Baikstiene, Vaida Diliene, Lina Siaudvytyte, Ingrida Januleviciene, Alon Harris   +6 more
doaj   +1 more source

Bilateral Angle‐Closure Glaucoma in the Context of Bilateral Choroidal Effusions Secondary to Campylobacter jejuni Infection

Case Reports in Ophthalmological Medicine, Volume 2026, Issue 1, 2026.
Choroidal effusion is characterised by fluid accumulation in the suprachoroidal space and can be either idiopathic or associated with trauma, infection, inflammation or intraocular surgery. On rare occasions, this can cause a secondary angle‐closure glaucoma that does not involve a pupil block mechanism.
Umme Kalsoom Alam, Ibtesham Tausif Hossain, Abdus Samad Ansari, Mark Westcott, Jonathan Clarke, Sara Al Hussein Al Awamlh   +5 more
wiley   +1 more source

Treatment of Retinitis Pigmentosa-Associated Cystoid Macular Oedema Using Intravitreal Aflibercept (Eylea) despite Minimal Response to Ranibizumab (Lucentis): A Case Report. [PDF]

, 2016
BACKGROUND: We present an interesting case of bilateral retinitis pigmentosa (RP)-associated cystoid macular oedema that responded on two separate occasions to intravitreal injections of aflibercept, despite previously demonstrating only minimal response
Gurbaxani, A, Michaelides, M, Strong, SA
core   +3 more sources

Aflatoxin B1 Impairs TACE Efficacy Through Downregulated Carbonic Anhydrase 2: A Bioinformatics Analysis

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer‐related mortality worldwide, and transcatheter arterial chemoembolization (TACE) remains the core locoregional therapeutic modality for patients with intermediate to advanced disease.
Pengsheng Zhang, Yuyun Tong, Xiran Feng, Qi Lan, Jiaping Wang, Zhijie Xu   +5 more
wiley   +1 more source

Episcleral Venous Pressure and the Ocular Hypotensive Effects of Topical and Intracameral Prostaglandin Analogs. [PDF]

, 2019
There is a limit beyond which increasing either the concentration of a prostaglandin analog (PGA) or its dosing frequency fails to produce increases in ocular hypotensive efficacy with topical dosing.
Alm, Blondeau, Brubaker, Celebi, Chen, Cymbor, Eveleth, Foroozan, Friberg, Funk, Funk, Katz, Krieglstein, Lee, Lee, Lee, Lewis, Lindén, Lovering, McDougal, Nagasubramanian, Ogundele, Phelps, Prum, Seal, Selbach, Selbach, Sherwood, Sit, Sit, Strohmaier, Tsai, Walløe, Watts, Wilke, Zamora, Zamora   +36 more
core   +2 more sources

The ocular hypotensive effect of saffron extract in primary open angle glaucoma: a pilot study [PDF]

, 2014
BACKGROUND: The progressive nature of glaucoma and its growing incidence make its therapy an important target for research. The role of oxidative damage in the pathogenesis of glaucoma makes antioxidants such as saffron extract an attractive target for ...
Mohammad Hossein Jabbarpoor Bonyadi, Saeed Saadat, Shahin Yazdani   +2 more
core   +1 more source

A novel stability indicating RP-HPLC method of related substances for dorzolamide hydrochloride and timolol maleate in glaucoma treatment ophthalmic formulation

Discover Chemistry
A sensitive and simultaneous RP-HPLC strategy has been developed for analysing timolol maleate and dorzolamide hydrochloride along with their related substances.
Harmeet Kaur Kohli, Satish K. Ghumare, Vijay A. Bagul   +2 more
doaj   +1 more source

Multimodal Imaging in the Diagnosis of Juvenile Retinoschisis: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Retinoschisis is a retinal disorder characterised by splitting within the neurosensory retina, which leads to structural disorganisation and varying degrees of visual loss.
Gufran Ali Kamdar, Shikha Rai, Sumit Navneet Toshniwal, (Col) Ok Radhakrishnan   +3 more
doaj   +1 more source

An Ilomastat-CD Eye Drop Formulation to Treat Ocular Scarring [PDF]

, 2017
PURPOSE: The purpose of this study was to develop a topical matrix metalloproteinase inhibitor preparation for antiscarring therapy. METHODS: The broad spectrum matrix metalloproteinase inhibitor ilomastat was formulated using 2-hydroxypropyl-β ...
Bailly, M, Brocchini, S, Khaw, PT, Li, H, Lockwood, A, Mohamed-Ahmed, AHA   +5 more
core   +1 more source