Results 61 to 70 of about 4,728 (163)

Toxicity and Physiological Actions of Carbonic Anhydrase Inhibitors to Aedes aegypti and Drosophila melanogaster

Insects, 2016
The physiological role of carbonic anhydrases in pH and ion regulation is crucial to insect survival. We examined the toxic and neurophysiological effects of five carbonic anhydrase inhibitors (CAIs) against Aedes aegypti.
Sheena A. M. Francis, Jennina Taylor-Wells, Aaron D. Gross, Jeffrey R. Bloomquist   +3 more
doaj   +1 more source

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

Arthritis &Rheumatology, Volume 78, Issue 4, Page 985-992, April 2026.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Topical dorzolamide for macular edema in the early phase after vitrectomy and epiretinal membrane removal

, 2013
Takahiro Suzuki, Kenji Hayakawa, Yoshihiro Nakagawa, Hiromi Onouchi, Masafumi Ogata, Kenji KawaiDepartment of Ophthalmology, Tokai University School of Medicine, Isehara, JapanBackground: The purpose of this study was to evaluate prospectively the ...
Kawai K, Suzuki T, Hayakawa K, Onouchi H, Nakagawa Y, Ogata M   +5 more
core  

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

Epilepsia, Volume 67, Issue 4, Page 1690-1702, April 2026.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei, Rachel Yui Ki Chu, Rachel Lancey Lai, Florinda Hui‐Ning Chu, Ian Yu Hin Leung, William Chun Yin Leung, Franco Wing Tak Cheng, Thomas Chi Ho Lam, Ian Chi Kei Wong, Esther Wai Yin Chan, Francisco Tsz Tsun Lai   +10 more
wiley   +1 more source

Comparisons of Intraocular-Pressure- Lowering Efficacy and Side Effects of 2% Dorzolamide and 1% Brinzolamide

, 2001
Forty-one healthy volunteers were recruited for a study to compare the intraocular pressure (IOP)-lowering efficacy and side effects of 2% dorzolamide and 1% brinzolamide.
성공제
core   +1 more source

Effects of association levobunolol-dorzolamide compared to timolol-dorzolamide on intraocular pressure and pulse rate in healthy dogs

, 2008
The purpose of this study was to determine whether the combination levobunolol-dorzolamide administered topically has any greater effects on the reduction of intraocular pressure (IOP) and pulse rate (PR) in healthy dogs than do timolol-dorzolamide ...
PUGLIESE, Michela, SCARDILLO, ALESSIO, DE MAJO, Massimo, NIUTTA, Pietro Paolo   +3 more
core  

Adjuvant topical dorzolamide or timolol with intravitreal bevacizumab for diabetic macular edema: A double-blind randomized controlled trial

Journal of Current Biomedical Reports
Diabetic macular edema (DME) is a leading cause of visual impairment among diabetic patients, primarily managed with intravitreal anti-VEGF agents such as bevacizumab. However, the exploration of adjunctive therapies to enhance treatment outcomes remains
Mohammadjavad Hafizi, Esmaeil Babaei, Mohsen Gohari   +2 more
doaj   +1 more source

Dorzolamide-timolol combination and retinal vessel oxygen saturation in patients with glaucoma or ocular hypertension

, 2009
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldAIMS: To examine whether the addition of dorzolamide to timolol monotherapy influences oxygen saturation in the human retina.
Hardarson, S H, Eysteinsson, T, Harris, A, Gottfredsdottir, M S, Traustason, S, Stefansson, E, Karlsson, R A   +6 more
core   +1 more source

A novel stability indicating RP-HPLC method of related substances for dorzolamide hydrochloride and timolol maleate in glaucoma treatment ophthalmic formulation

Discover Chemistry
A sensitive and simultaneous RP-HPLC strategy has been developed for analysing timolol maleate and dorzolamide hydrochloride along with their related substances.
Harmeet Kaur Kohli, Satish K. Ghumare, Vijay A. Bagul   +2 more
doaj   +1 more source

The effect of dorzolamide on intraocular pressure

, 1998
Bu çalışmada topikal karbonik anhidraz inhibitörü olan %2 'lik dorzolamidin Göziçi basıncı (GİB) üzerine olan etkisi plasebo kontrollü olarak araştırıldı. Çalışmaya GİB en az 22mmHg ve üzerinde olan 28 primer açık açılı glokomlu hasta alındı.
Cenap Güler, Ayşen Topalkara, Mustafa Kemal Arıcı   +2 more
core   +1 more source