Results 41 to 50 of about 3,606 (169)

Comparison of Intraocular Pressure, Blood Pressure, Ocular Perfusion Pressure and Blood Flow Fluctuations During Dorzolamide Versus Timolol Add-On Therapy in Prostaglandin Analogue Treated Glaucoma Subjects

open access: yesPharmaceuticals, 2012
Objective: To compare the effects of dorzolamide and timolol add-on therapy in open-angle glaucoma (OAG) patients previously treated with prostaglandin analogue (Pg), by evaluating fluctuations in the intraocular (IOP), blood (BP), ocular perfusion ...
Ruta Barsauskaite   +6 more
doaj   +1 more source

6‐Methylsulfinylhexyl isothiocyanate activates carbonic anhydrase‐dependent HCO3−/H+/Na+/Ca2+ transport via SLC4As–NHE–NCX–PMCA axis in odontoblasts

open access: yesThe Journal of Physiology, Volume 604, Issue 7, Page 2816-2844, 1 April 2026.
Abstract figure legend 6‐Methylsulfinylhexyl isothiocyanate (6‐MSITC, hexaraphane), a wasabi sulfinyl compound, activates intracellular carbonic anhydrase (CA)‐mediated sequential HCO3−, Na+, H+ and Ca2+ transport through an activation axis involving HCO3−‐transporting solute carrier family 4 (SLC4As), the Na+–H+ exchanger (NHE), the Na+–Ca2+ exchanger
Yoshiaki Furusawa   +9 more
wiley   +1 more source

A patient preference comparison of Azarga™ (brinzolamide/timolol fixed combination) vs Cosopt® (dorzolamide/timolol fixed combination) in patients with open-angle glaucoma or ocular hypertension

open access: yesClinical Ophthalmology, 2008
Thomas K Mundorf1, Steven H Rauchman2, Robert D Williams3, Ricardo Notivol4, Brinzolamide/Timolol Preference Study Group51Mundorf Eye Center, Charlotte, NC, USA; 2North Valley Eye Medical Group, Mission Hills, CA, USA; 3Taustine Eye Center, Louisville ...
Thomas K Mundorf   +4 more
doaj  

Multimodal Imaging in the Diagnosis of Juvenile Retinoschisis: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Retinoschisis is a retinal disorder characterised by splitting within the neurosensory retina, which leads to structural disorganisation and varying degrees of visual loss.
Gufran Ali Kamdar   +3 more
doaj   +1 more source

A Pilot Investigation of Transforming Growth Factor‐β2 and Total Protein Concentrations in Aqueous Humor of Canine Glaucomatous Eyes With and Without Ahmed Glaucoma Valve Surgery

open access: yesVeterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objective To investigate responses to surgical interventions in concentrations of transforming growth factor‐β2 (TGF‐β2) and total protein (TP) in the aqueous humor (AH) of primary angle‐closure glaucoma (PACG) eyes, with and without Ahmed glaucoma valve surgery in dogs.
Songhui Lee, Kangmoon Seo, Seonmi Kang
wiley   +1 more source

Toxicity and Physiological Actions of Carbonic Anhydrase Inhibitors to Aedes aegypti and Drosophila melanogaster

open access: yesInsects, 2016
The physiological role of carbonic anhydrases in pH and ion regulation is crucial to insect survival. We examined the toxic and neurophysiological effects of five carbonic anhydrase inhibitors (CAIs) against Aedes aegypti.
Sheena A. M. Francis   +3 more
doaj   +1 more source

Effects of Omidenepag Isopropyl Versus Latanoprost Eye Drops on Intraocular Pressure, Pupil Diameter, and Anterior Chamber Parameters in Normal Feline Eyes: A Pilot Study

open access: yesVeterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objectives This study aimed to compare the effect of the newly developed selective prostaglandin E2 receptor agonist, omidenepag isopropyl (OMDI), and latanoprost on intraocular pressure (IOP), pupil diameter (PD), and anterior chamber parameters in normal feline eyes.
Sang‐Eun Park   +5 more
wiley   +1 more source

Preoperative and Intraoperative Risk Factors for Short‐Term Corneal Endothelial Cell Loss After Phacoemulsification in Dogs: A Comparative Study

open access: yesVeterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objective To investigate the short‐term impact of phacoemulsification on corneal endothelial cells and corneal thickness and identify associated risk factors. Animal Studied Twenty‐four dogs (33 eyes) scheduled for phacoemulsification to treat cataracts were evaluated.
Tae‐Won Yoon, Joon‐Young Kim
wiley   +1 more source

Efficacy, safety and tolerability of combination therapy with timolol and dorzolamide in glaucoma and ocular hypertension

open access: yesDrug, Healthcare and Patient Safety, 2010
Parul Ichhpujani1,2, L Jay Katz11William and Anna Goldberg Glaucoma Service, 1Wills Eye Institute, Philadelphia, PA, USA; 2Department of Ophthalmology, Government Medical College and Hospital, Chandigrah, IndiaAbstract: Combination pharmacotherapy has ...
Parul Ichhpujani, L Jay Katz
doaj  

Adjuvant topical dorzolamide or timolol with intravitreal bevacizumab for diabetic macular edema: A double-blind randomized controlled trial

open access: yesJournal of Current Biomedical Reports
Diabetic macular edema (DME) is a leading cause of visual impairment among diabetic patients, primarily managed with intravitreal anti-VEGF agents such as bevacizumab. However, the exploration of adjunctive therapies to enhance treatment outcomes remains
Mohammadjavad Hafizi   +2 more
doaj   +1 more source

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