Results 31 to 40 of about 4,450 (205)

Optic nerve oxygen tension: the effects of timolol and dorzolamide.

, 2004
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldBACKGROUND/AIMS: The authors have previously reported that carbonic anhydrase inhibitors such as acetazolamide and dorzolamide raise optic nerve
Bang, K, Eysteinsson, T, la Cour, M, Kiilgaard, J F, J F Kiilgaard, Pedersen, D.B., Cour, M. la, Kiilgaard, Jens Folke, Pedersen, D B, Bang, K., Jensen, P K, Eysteinsson, T., Stefánsson, E., Stefansson, E, Kiilgaard, J.F., Jensen, P.K.   +15 more
core   +1 more source

Comparative study to assess efficacy and safety of brinzolamide1% and timolol0.5% fixed combination eye drops versus dorzolamide2% and timolol0.5% fixed combination eye drops in management of open-angle glaucoma

Journal of Family Medicine and Primary Care, 2022
Aim and Objective: To compare the efficacy and safety of brinzolamide1% and timolol0.5% fixed combination eye drops versus dorzolamide2% and timolol0.5% fixed combination eye drops in the treatment of primary open-angle glaucoma.
Prerana Agarwal, Suryadev Tayal, Ankur Gautum   +2 more
doaj   +1 more source

Micropulse transscleral cyclophotocoagulation in canine glaucoma: A retrospective study evaluating sweep velocity

Veterinary Ophthalmology, Volume 28, Issue 2, Page 293-305, March 2025.
Abstract Objective To report preliminary results of MP‐TSCP in canine patients with glaucoma while evaluating sweep velocity, treatment efficacy, and safety utilizing standardized surgical parameters. Animal studied Client‐owned dogs that underwent MP‐TSCP at a veterinary referral hospital. Procedure Medical records of 19 eyes (14 dogs) treated with MP‐
Valeria Benitez‐Vera, Dineli Bras, Fabiano Montiani‐Ferreira   +2 more
wiley   +1 more source

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

Veterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour, Julie A. Cohen, Charles‐Antoine Assenmacher, Dolores M. Holle, Amy C. Durham, Gustavo D. Aguirre, Keiko Miyadera   +6 more
wiley   +1 more source

Allergic contact dermatitis to dorzolamide and benzalkonium chloride

, 2018
Dorzolamide is a topical carbonic anhydrase II and XII inhibitor that can be administered topically, directly into the eye, as a 2% water solution. Common side e ects are conjunctivitis, erythema and eyelid edema.
Cristaudo A., Pigliacelli F., Assorgi C., D'Arino A., Latini A., Orsini D.   +5 more
core   +1 more source

Two Cases of Fibrin Membrane‐Induced Pupillary Block Treated With Neodymium‐Doped Yttrium Aluminium Garnet (Nd:YAG) Laser After Cataract Surgery in Dogs

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study evaluates the clinical efficacy of Nd:YAG laser membranotomy in dogs with fibrin membrane‐induced pupillary block (FMPB). Targeted application of the Nd:YAG laser safely disrupts the obstructive pupillary membrane, thereby restoring normal aqueous humour outflow and effectively resolving secondary intraocular pressure (IOP) elevation without
Haerin Yoon, Jiyi Hwang, Ji Seung Jung, Myeon‐Jee Kwon, Jungyeon Yong, Sungin Lee, Kyung‐Mee Park   +6 more
wiley   +1 more source

Clinical Features and Surgical Outcomes of Cats With Presumed Primary Lens Instability: A Retrospective Study of 34 Cases (2018–2022)

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective Describe the clinical features, disease progression, and outcomes of presumed primary lens instability (PLI) in cats, and to assess its association with glaucoma. Animals Studied Thirty‐four cats (68 eyes). Procedures Medical records were reviewed for signalment, clinical history, ophthalmic findings, and treatment.
Havi Sarfaty, Raaya Ezra‐Elia, Nili Kahane, Shai Sandalon, Yifat Segev, Lionel Sebbag   +5 more
wiley   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

The evolving role of structural biology in pharma: integration of X‐ray crystallography, cryo‐electron microscopy and beyond

Acta Crystallographica Section D, Volume 82, Issue 6, Page 587-602, June 2026.
This review describes how an integrated structural biology platform at Merck Sharp & Dohme LLC, Rahway, New Jersey, USA, combining X‐ray crystallography, cryo‐EM, MicroED and cryo‐ET, enables seamless three‐dimensional insights from molecular to cellular length scales.
Jill E. Chrencik, Hua-Poo Su, Yacob Gomez Llorente, Rachel L. Palte, Daniel J. Klein, Robert P. Hayes, Sadie P. Antine, Guilermo A. Asmar-Rovira, Nicole Bertoletti, Noel J. Byrne, Brittany L. Carroll, Ciro D. Cordeiro, Kaylynn Curfman, James Dutko, Michael J. Eddins, Thierry Fischmann, Barani Govindarajan, Corey W. Hecksel, Thu Ho, Kaspar Hollenstein, Mee Ra Hong, Alan Hruza, Andrii Ishchenko, Maru Jaime-Garza, Matt J. Jaremko, Hayley L. Knox, James Kostas, Harini Krishnamurthy, Ioannis Manolaridis, Cameron L. Noland, Andrea T. Partridge, Sangita B. Patel, Paul Reichert, John C. Reid, Catarina Felisberto-Rodrigues, Chitra A. Shintre, Jennifer M. Shipman, Elakkiya Tamilselvan, Morgan E. Walker, Susanne N. Walker, Renjing Wang, Katharine M. Wright, Tien-Jui Yen, Byung-Kuk Yoo, Sandra B. Gabelli   +44 more
wiley   +1 more source

New Opportunities in Non-Preservative Glaucoma Therapy

Oftalʹmologiâ, 2021
Most of the medicines used for the treatment of glaucoma include a preservative in various concentrations. With long-term topical therapy, patients with glaucoma may develop dry eye syndrome (DES).
A. A. Antonov, I. V. Kozlova, A. A. Vitkov   +2 more
doaj   +1 more source