Results 11 to 20 of about 9,342 (307)
Indian Journal of Ophthalmology, 2022 Purpose: Impaired ocular blood flow is an important risk factor in the pathogenesis of open-angle glaucoma (OAG). Studies have reported that dorzolamide 2% may be effective in improving ocular blood flow (OBF) in OAG patients. The objective of this study
Pratheeba D Nivean +5 more
doaj +2 more sources
Journal of Medical Case Reports, 2021 Background Cystoid macular edema is a rare, vision-threatening side effect of the taxane family of anticancer agents. There is no established treatment or standard treatment protocol for taxane-related cystoid macular edema.
Mitsuru Otsubo +3 more
doaj +2 more sources
Al-Azhar International Medical Journal, 2022 Background: Diabetic macular edema (DME) is a main reason for vision affection when occurred at any stage of diabetic retinopathy. Anti-vascular endothelial growth factor agents is the gold standard treatment for DME.
Sara Gadwal +2 more
openalex +3 more sources
Dorzolamide Suppresses PKCδ -TIRAP-p38 MAPK Signaling Axis to Dampen the Inflammatory Response
Future Medicinal Chemistry, 2023 Background: Sepsis is a syndrome due to microbial infection causing impaired multiorgan function. Its underlying cause is immune dysfunction and macrophages play an essential role. Methods: TIRAP interaction with PKCδ in macrophage was studied, revealing
Sajjan Rajpoot +9 more
openalex +2 more sources
Retrospective Assessment of Carbonic Anhydrase Inhibitors in Topical or Episcleral Implant Form for the Treatment of Equine Glaucoma. [PDF]
Vet OphthalmolABSTRACT Objective To assess whether topical carbonic anhydrase inhibitors (CAIs) with or without episcleral brinzolamide implants control intraocular pressure (IOP) in horses with glaucoma. Animals Studied 12 client‐owned horses diagnosed with glaucoma.
Tucker-Retter EK +3 more
europepmc +2 more sources
Resolution of bilateral foveal cysts in dome-shaped macula after treatment with topical dorzolamide
BMJ Case Reports, 2021 Dome-shaped macula (DSM) is characterised by a convex anterior bulging of the macular area. It can further get complicated by accumulation of subretinal fluid (SRF).
Tejaswini Vukkadala +3 more
openalex +3 more sources
Advances in dorzolamide hydrochloride delivery: harnessing nanotechnology for enhanced ocular drug delivery in glaucoma management. [PDF]
Discov NanoDorzolamide hydrochloride (DRZ) is a carbonic anhydrase inhibitor utilized in managing elevated intraocular pressure (IOP) associated with glaucoma. However, its clinical effectiveness is hindered by a short half-life, low residence time, and the need ...
Pardeshi SR +5 more
europepmc +2 more sources
BMC Chemistry, 2023 Three smart carbon paste electrodes were fabricated to quantify dorzolamide hydrochloride DRZ, including conventional carbon paste I, modified carbon paste embedding Silica II, and modified carbon paste embedding β-cyclodextrin III.
Mai M. Mora +3 more
semanticscholar +1 more source
Efficacy and Safety of a Fixed-Dose Combination of Brinzolamide 1%/Timolol 0.5% vs. Dorzolamide 2%/Timolol 0.5% in Indian Patients With Primary Open-Angle Glaucoma or Ocular Hypertension: A Randomized Phase 3 Study. [PDF]
CureusIntroduction Fixed-dose combinations (FDCs) have the potential in glaucoma management to improve efficacy due to the complementary mechanism of action of the drugs as well as compliance while reducing adverse effects by minimizing exposure to ...
Bhagat P +9 more
europepmc +2 more sources
Indian Journal of Ophthalmology, 2023 Yes, it is a good suggestion. Literature has enough evidence to prove that dorzolamide eye drops increase the ocular blood flow when compared with timolol[4] and latanoprost.[5] But in our study, we had studied the efficacy of only dorzolamide as it was ...
M. Ariga, P. Nivean
semanticscholar +1 more source