Comparison of the efficacy and safety of fixed combination travoprost/timolol and dorzolamide/timolol in patients with primary open-angle glaucoma and ocular hypertension [PDF]
Introduction. Combining two medications in one bottle may improve compliance by reducing the time required to administer drops and the frequency of the total number of medication bottles. Objective.
Babić Nikola +4 more
doaj +1 more source
Stereoselective Solvolysis in the Synthesis of Dorzolamide Intermediates
The key intermediate in the synthesis of dorzolamide, (4S,6S)-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol-7,7-dioxide, can be obtained in the diastereoisomerically pure form in two straightforward steps starting from diastereoisomeric mixtures of ...
A. Martinelli +6 more
semanticscholar +1 more source
Dramatic response to topical dorzolamide in X-linked retinoschisis
Macular involvement is commonly seen in cases with X-linked retinoschisis (XLRS) which includes foveal schisis and cystic maculopathy. Although no definitive treatment has been described, the use of topical 2% dorzolamide hydrochloride in such cases has ...
Rajeswari Thangavel +3 more
doaj +1 more source
Management of canine glaucoma using a combination of dorzolamide and timolol
A study was conducted in twelve glaucomatous dogs to assess the efficacy of the combination of dorzolamide and timolol in the treatment of glaucoma in dogs. The study included twelve dogs with glaucoma of any age, breed, or gender.
Shubham W. Raut +5 more
semanticscholar +1 more source
Effect of topical dorzolamide on rabbit central corneal thickness
Our objective was to study the effect of dorzolamide on corneal hydration in an 18-week controlled experiment using ultrasonic pachymetry. Twenty-eight male rabbits were divided randomly into four groups.
G.C. Almeida Jr., S.J. Faria e Souza
doaj +1 more source
Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension. [PDF]
Glaucoma is a collection of diseases characterized by multifactorial progressive changes leading to visual field loss and optic neuropathy most frequently due to elevated intraocular pressure (IOP).
Bell, Nicholas P +2 more
core +3 more sources
Rare diseases leading to childhood Glaucoma. epidemiology, pathophysiogenesis, and management [PDF]
Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of
Abdolrahimzadeh, Solmaz +5 more
core +3 more sources
Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle glaucoma [PDF]
Anastasios G. P. Konstas +7 more
openalex +2 more sources
The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A review [PDF]
The acute and chronic effects of repeated intravitreal antivascular endothelial growth factor (VEGF) injections on intraocular pressure have not been fully characterized, and the development of sustained ocular hypertension could adversely affect ...
Bracha, Peter +4 more
core +1 more source
24-h Efficacy of Glaucoma Treatment Options [PDF]
Current management of glaucoma entails the medical, laser, or surgical reduction of intraocular pressure (IOP) to a predetermined level of target IOP, which is commensurate with either stability or delayed progression of visual loss.
Banu, Bozkurt. +8 more
core +2 more sources

