Results 31 to 40 of about 5,860 (250)

Comparison of the efficacy and safety of fixed combination travoprost/timolol and dorzolamide/timolol in patients with primary open-angle glaucoma and ocular hypertension [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2013
Introduction. Combining two medications in one bottle may improve compliance by reducing the time required to administer drops and the frequency of the total number of medication bottles. Objective.
Babić Nikola, Andreić Veljko, Miljković Aleksandar, Grković Desanka, Jovanović Predrag   +4 more
doaj   +1 more source

The Additive Effect of Topical Dorzolamide-Timolol with Intravitreal Ranibizumab Injection in Diabetic Macular Edema

Al-Azhar International Medical Journal, 2022
Background: Diabetic macular edema (DME) is a main reason for vision affection when occurred at any stage of diabetic retinopathy. Anti-vascular endothelial growth factor agents is the gold standard treatment for DME.
Sara Gadwal, W. Madbouly, Mona Mansour
semanticscholar   +1 more source

New Opportunities in Non-Preservative Glaucoma Therapy

Oftalʹmologiâ, 2021
Most of the medicines used for the treatment of glaucoma include a preservative in various concentrations. With long-term topical therapy, patients with glaucoma may develop dry eye syndrome (DES).
A. A. Antonov, I. V. Kozlova, A. A. Vitkov   +2 more
doaj   +1 more source

Whiter and Greener RP-HPLC Method for Simultaneous Determination of Dorzolamide, Brinzolamide, and Timolol Using Isopropanol as a Sustainable Organic Solvent in the Mobile Phase

Separations
A sustainable reversed-phase chromatographic method has been developed and validated for the simultaneous determination of three active pharmaceutical ingredients, dorzolamide, brinzolamide, and timolol, used to treat glaucoma.
Sami El Deeb, Khalid Abdelsamad, M. K. Parr   +2 more
semanticscholar   +1 more source

A comparative evaluation of the efficacy and safety of Latanoprost-Optic and Xalatan used as monotherapy and combined with Dorzolamide-Optic for primary open-angle glaucoma under clinical practice conditions

Российский офтальмологический журнал, 2023
The number of ophthalmic antihypertensive drugs available in Russia is steadily increasing, which complicates the choice to be made by ophthalmologist practitioners.
D. P. Novikov, O. A. Frolov, A. S. Pokrovsky, V. V. Novikova   +3 more
doaj   +1 more source

Topical dorzolamide for macular holes: A randomised, double‐blind, placebo‐controlled trial

Clinical and Experimental Ophthalmology
To assess topical dorzolamide as medical therapy for idiopathic full‐thickness macular holes (FTMHs).
Yong Min Lee, Bobak Bahrami, Duleepa Baranage, P. Sivagurunathan, Wilson Wong, M. M. Bausili, Surbhi Agrawal, J. Gilhotra, Shane Durkin, David Sia, Dinesh Selva, Stewart Lake, Robert J. Casson, Weng Onn Chan   +13 more
semanticscholar   +1 more source

Allergic contact dermatitis to dorzolamide and benzalkonium chloride [PDF]

Advances in Dermatology and Allergology, 2018
Dorzolamide is a topical carbonic anhydrase II and XII inhibitor that can be administered topically, directly into the eye, as a 2% water solution. Common side e ects are conjunctivitis, erythema and eyelid edema. To the best of our knowledge, true contact dermatitis to Dorzolamide is rare and only a few cases have been reported in the literature..
Orsini D., D'Arino A., Pigliacelli F., Assorgi C., Latini A., Cristaudo A.   +5 more
openaire   +4 more sources

Formulation and evaluation of Dorzolamide hydrochloride microsponges loaded in situ gel for ocular administration

World Journal of Biology Pharmacy and Health Sciences
Due to the unique structure of the eye, which inhibits the entry of drug molecules into the desired site, the ophthalmic delivery of the drug has been one of the most challenging tasks for a pharmaceutical scientist.
G. Rathnam, G. Sangeetha
semanticscholar   +1 more source

Bilateral Choroidal Detachment in the Absence of Previous Intraocular Surgery

Case Reports in Ophthalmology, 2022
The aim of this report was to present a case of bilateral choroidal detachment following treatment with topical therapy dorzolamide/timolol without history of previous surgery.
Maria J. Chaves-Samaniego, Aleyda Molina Lespron, Zaira Cervera Sanchez, Pedro Amat Peral, José M. Ruiz Moreno   +4 more
doaj   +1 more source

A NEW RP-UPLC METHOD FOR THE SEPARATION AND SIMULTANEOUS QUANTIFICATION OF DORZOLAMIDE HCl AND TIMOLOL MALEATE

International Journal of Applied Pharmaceutics
Objective: This investigation demonstrates a stability-indicating and reliable “reverse-phase ultra-performance liquid chromatography” method to simultaneously quantify timolol maleate and dorzolamide HCl in the pharmaceutical dosage form.
Asha Eluru, K. S. Babu
semanticscholar   +1 more source